Cellular cap-binding proteins associate with influenza virus mRNAs. door Bier, K, York, A, Fodor, E

“…The influenza virus RNA polymerase synthesizes three types of RNA: genomic vRNA, anti-genomic cRNA and mRNA. …”

Hsp90 inhibitors reduce influenza virus replication in cell culture. door Chase, G, Deng, T, Fodor, E, Leung, B, Mayer, D, Schwemmle, M, Brownlee, G

“…Hsp90 inhibitors may represent a new class of antiviral compounds against influenza viruses.…”

Influenza virus RNA polymerase: insights into the mechanisms of viral RNA synthesis door Fodor, E, te Velthuis, A

“…The genome of influenza viruses consists of multiple segments of single stranded negative-sense RNA. …”

Role of the influenza virus heterotrimeric RNA polymerase complex in the initiation of replication. door Deng, T, Sharps, J, Brownlee, G

“…Both transcription and replication of the influenza virus RNA genome are catalysed by a virus-specific RNA polymerase. …”

The role of respiratory epithelium in host defence against influenza virus infection door Denney, L, Ho, L

“…Sophisticated barrier, sensing, anti-microbial and immune regulatory mechanisms have evolved to help maintain homeostasis and to defend the lung against foreign substances and pathogens. During influenza virus infection, these specialised structural cells and populations of resident immune cells come together to mount the first response to the virus, one which would play a significant role in the immediate and long term outcome of the infection. …”

Estimating reassortment rates in co-circulating Eurasian swine influenza viruses door Lycett, S, Baillie, G, Coulter, E, Bhatt, S, Kellam, P, McCauley, J, Wood, J, Brown, I, Pybus, O, Brown Leigh, A

“…We analysed 69 newly obtained whole genome sequences of subtypes H1N1-H3N2 from swine influenza viruses sampled between 1982 and 2008, using Illumina and 454 platforms. …”

Estimating reassortment rates in co-circulating Eurasian swine influenza viruses. door Lycett, S, Baillie, G, Coulter, E, Bhatt, S, Kellam, P, McCauley, J, Wood, J, Brown, I, Pybus, O, Leigh Brown, A

“…We analysed 69 newly obtained whole genome sequences of subtypes H1N1-H3N2 from swine influenza viruses sampled between 1982 and 2008, using Illumina and 454 platforms. …”

Model suggesting that replication of influenza virus is regulated by stabilization of replicative intermediates. door Vreede, F, Jung, T, Brownlee, G

Study of the structure and function of the influenza virus RNA-dependent RNA polymerase door Martin, I

“…<p>Influenza viruses are segmented, negative-sense RNA viruses responsible for influenza disease. …”

Antibody responses to avian influenza viruses in wild birds broaden with age door Hill, S, Manvell, R, Schulenburg, B, Shell, W, Wikramaratna, P, Perrins, C, Sheldon, B, Brown, I, Pybus, O

“…The accumulation of acquired immunity with age is hypothesized to affect how influenza viruses emerge and spread in species of different lifespans. …”

Functional reconstitution of the integral membrane proteins of influenza virus into phospholipid liposomes. door Sizer, P, Miller, A, Watts, A

“…The integral membrane proteins of influenza virus, a hemagglutinin and a neuraminidase, have been incorporated into liposomes composed of either phosphatidylcholine or a mixture of phosphatidylcholine and phosphatidylethanolamine (2:1 w/w) using detergent dialysis. …”

Production of human monoclonal antibody to X31 influenza virus nucleoprotein. door Crawford, D, Callard, R, Muggeridge, M, Mitchell, D, Zanders, E, Beverley, P

“…In vitro stimulation of human peripheral blood mononuclear cells with X31 influenza virus antigen has been used to enrich for specific anti-X31 antibody-producing cells. …”

Contribution of innate immune cells to pathogenesis of severe influenza virus infection. door Cole, S, Ho, L

Phylodynamics of H5N1 avian influenza virus in Indonesia. door Lam, T, Hon, C, Lemey, P, Pybus, O, Shi, M, Tun, H, Li, J, Jiang, J, Holmes, E, Leung, F

“…H5N1 highly pathogenic avian influenza virus (HPAIV) is a major animal pathogen and public health threat. …”

Specificity of cytotoxic T lymphocytes stimulated with influenza virus. Studies in mice and humans. door Townsend, A, Mcmichael, A

“…In this review we discuss the recognition of influenza virus antigens in association with MHC class-I molecules in both mouse and man. …”

Rapid electrochemical detection of single influenza viruses tagged with silver nanoparticles door Sepunaru, L, Plowman, B, Sokolov, S, Young, N, Compton, R

“…A solution containing a low concentration of influenza virus is exposed to silver nanoparticles which are adsorbed onto the virus surface, as revealed by UV-Vis spectroscopy and transmission electron microscopy. …”

Structure of a H3N2 influenza virus nucleoprotein door Knight, M, Fan, H, Bauer, D, Grimes, J, Fodor, E, Keown, J

“…Here, the structure of the A/Northern Territory/60/1968 (H3N2) influenza virus NP is presented at 2.2 Å resolution. The structure is highly similar to those of the A/WSN/1933 (H1N1) and A/Hong Kong/483/97 (H5N1) NPs. …”

Phylodynamics of H5N1 avian influenza virus in Indonesia door Lam, T, Hon, C, Lemey, P, Pybus, O, Shi, M, Tun, H, Li, J, Jiang, J, Holmes, E, Leung, F

“…H5N1 highly pathogenic avian influenza virus (HPAIV) is a major animal pathogen and public health threat. …”

Cloning and expression of equine influenza virus nonstructural gene in prokaryotic system door Abdulhadi, Abdulrahman Dahham, Fateh Mohamed, Bashir Ahmad, Omar, Abdul Rahman, Bejo, Mohd Hair

“…Equine influenza virus (EIV) is a highly contagious and widely distributed viral respiratory disease of equiadae caused by type A influenza virus from the family Orthomyxovirus. …”
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The prevention of H5N1 avian influenza: inactivated low pathogenicity avian influenza virus-based vaccine against high pathogenicity avian influenza virus strain door Natalya V. Moroz, Dmitry L. Dolgov, Ilya А. Chvala, Sergey V. Frolov, Аlyona D. Grekhneva, Vladimir Yu. Kulakov

“…High pathogenicity avian influenza viruses cause devastating epizooties leading to significant economic losses. …”
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