Comparison treatment of medium-sized volar fingertips defects with modified triangular neurovascular unilateral advancement flap versus digital artery dorsal perforator flap by Lixi Zhu, Feiya Zhou, Xian Zhang, Xue Zhang, Pinghu Jin

“…The general information of the two groups showed no significant differences in age, sex, injury side, cause of injury, time from injury to surgery, and operation time (P > 0.05). …”
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Analysis of the dynamic co-expression network of heart regeneration in the zebrafish by Sophie Rodius, Anna Fournier, Lou Götz, Robin Liechti, Isaac Crespo, Susanne Merz, Petr V. Nazarov, Niek de Klein, Céline Jeanty, Juan M. González-Rosa, Arnaud Muller, Francois Bernardin, Simone P. Niclou, Laurent Vallar, Nadia Mercader, Mark Ibberson, Ioannis Xenarios, Francisco Azuaje

“…Across multiple post-injury time points, the network displays topological attributes of biological relevance. …”
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Agreement between arterial and end-tidal carbon dioxide in adult patients admitted with serious traumatic brain injury. by Neil Sardesai, Owen Hibberd, James Price, Ari Ercole, Ed B G Barnard

“…ETCO2 may not be an adequate proxy to guide ventilation and the effects on concomitant injury, time, and the impact of ventilatory strategies on the PaCO2-ETCO2 gradient are not well understood. …”
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Investigating microRNAs as biomarkers in disorders of consciousness: a longitudinal multicenter study by Nicolò Musso, Dalida Bivona, Carmelo Bonomo, Paolo Bonacci, Maria Enza D’Ippolito, Cristina Boccagni, Francesca Rubino, Antonio De Tanti, Lucia Francesca Lucca, Valeria Pingue, Valentina Colombo, Anna Estraneo, Stefania Stefani, Maria Andriolo, Sergio Bagnato

“…This study highlights distinct miRNA dysregulated patterns in patients with prolonged DoC, dependent on etiology and post-injury time, and suggests that miRNAs 132-3p and 23b-3p may serve as prognostic biomarkers.…”
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Screening criteria of mRNA indicators for wound age estimation by Qiuxiang Du, Tana Dong, Yuanxin Liu, Xiyan Zhu, Na Li, Lihong Dang, Jie Cao, Qianqian Jin, Junhong Sun

“…In the present study, the feasibility of screening criteria using mRNA to determine injury time based on the adenylate-uridylate-rich element (ARE) structure and gene ontology (GO) categories were evaluated. …”
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Murine Neonatal Oxidant Lung Injury: NRF2-Dependent Predisposition to Adulthood Respiratory Viral Infection and Protection by Maternal Antioxidant by Hye-Youn Cho, Laura Miller-DeGraff, Ligon A. Perrow, Wesley Gladwell, Vijayalakshmi Panduri, Fred B. Lih, Steven R. Kleeberger

“…To investigate the prenatal antioxidant effect on neonatal oxidative lung injury, time-pregnant <i>Nrf2</i>^−/− and <i>Nrf2</i>^+/+ mice were given an oral NRF2 agonist (sulforaphane) on embryonic days 11.5–17.5, and offspring were exposed to hyperoxia. …”
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Partial Fibular Head Osteotomy is an Alternative Option in Treatment of Posterolateral Tibial Plateau Fractures: A Retrospective Analysis by Yao Lu, Yao Lu, Gen Wang, Cheng Ren, Yibo Xu, Qiang Huang, Shan Fan, Ming Li, Kun Zhang, Zhong Li, Qian Wang, Teng Ma

“…Computed tomography was performed for fracture typing and evaluation. The mode of injury, time from injury to surgery, time for fracture union, range of motion of the knee, and complications were recorded. …”
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Contralateral synaptic changes following severe unilateral brain injury by Yuan Zhuang, Jinqian Dong, Qianqian Ge, Bin Zhang, Mengshi Yang, Shenghua Lu, Hao Li, Fei Niu, Xiaojian Xu, Baiyun Liu

“…These rats were further divided into three subgroups according to post-injury time: 7 days, 14 days, and 30 days post-injury. …”
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Cerebrospinal fluid levels of neuroinflammatory biomarkers are increased in athletes with persistent post-concussive symptoms following sports-related concussion by Anna Gard, Fredrik Vedung, Fredrik Piehl, Mohsen Khademi, Maria Portonova Wernersson, Ia Rorsman, Yelverton Tegner, Hélène Pessah-Rasmussen, Karsten Ruscher, Niklas Marklund

“…Limitations include evaluation at a single post-injury time point in relatively small cohorts, and no control group of concussed athletes without persisting symptoms was included. …”
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A systematic review of ankle fracture-dislocations: Recent update and future prospects by Mu-Min Cao, Mu-Min Cao, Mu-Min Cao, Mu-Min Cao, Yuan-Wei Zhang, Yuan-Wei Zhang, Yuan-Wei Zhang, Yuan-Wei Zhang, Sheng-Ye Hu, Sheng-Ye Hu, Sheng-Ye Hu, Sheng-Ye Hu, Yun-Feng Rui, Yun-Feng Rui, Yun-Feng Rui, Yun-Feng Rui

“…The detailed information was extracted for each article, such as researchers, age, gender, groups, type of study, type of center research, level of evidence, significant findings, study aim, cause of injury, time from injury to surgery, type of fracture, direction of dislocation, follow-up, postoperative complications and functional evaluation scores.ResultsA total of 15 studies (1,089 patients) met the inclusion criteria. …”
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Outcomes and associated factors of traumatic brain injury among adult patients treated in Amhara regional state comprehensive specialized hospitals by Solomon G/Michael, Bewuketu Terefe, Marye Getnet Asfaw, Bikis Liyew

“…Conclusion and recommendation In this study, the overall unfavorable outcome was experienced by about four out of every 10 victims of traumatic brain injury. Time of arrival > 24 h, low Glasgow coma scale, additional injury, Cerebrospinal fluid otorrhea, abnormal respiration, and hypoxia were significant predictors of unfavorable outcomes. …”
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Clinical performance of a multiparametric MRI-based post concussive syndrome index by Steven P. Meyers, Adnan Hirad, Patricia Gonzalez, Jeffrey J. Bazarian, Mark H. Mirabelli, Katherine H. Rizzone, Heather M. Ma, Peter Rosella, Saara Totterman, Edward Schreyer, Jose G. Tamez-Pena

“…The PCSI values for patients with PCS were compared based on the mechanism of injury, time interval from injury to MRI examination, sex, history of prior concussion, loss of consciousness, and reported symptoms.ResultsInjured patients had a mean PCSI value of 0.57, compared to the control group, which had a mean PCSI value of 0.12 (p = 8.42e-23) with accuracy of 88%, sensitivity of 64%, and specificity of 95%, respectively. …”
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Treatment of Delayed Acetabular Fractures by Periacetabular Osteotomy through the Lateral‐Rectus Approach by Haibo Xiang, Xiaodong Yang, Zhuobin Huang, Wenquan Xu, Yuhui Chen, Tao Li, Hai Huang, Shicai Fan

“…Fracture classification, mechanism of injury, associated injury, time to surgery, operation time, intraoperative blood loss, and complications were recorded and analyzed. …”
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Risk factors associated with tendon adhesions after hand tendon repair by Qiyu Jia, Dongsheng Chen, Jian Guo, Xuefeng Luo, Abudusalamu Alimujiang, Jun Zhang, Ningning Hu, Yanshi Liu, Zengru Xie, Chuang Ma

“…The risk factors for the total sample in the descending order were degloving injury, no functional exercise, zone II flexor tendon injury, time from injury to surgery &gt;12 h, combined vascular injury, and multiple tendon injuries. …”
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Effect of Age on the Patterns of Traumatic Femoral Fractures: Seven Years of Experience at a Regional Tertiary Hospital by Hong Yuan, Hailong Yu, Yunpeng Zhu, Liangbi Xiang, Hongwei Wang

“…There were significant differences among the three groups in several indexes, such as sex ratio (χ2 = 301.699, p < 0.001), osteoporosis (χ2 = 375.463, p < 0.001), injury time of day (χ2 = 114.913, p < 0.001), injury cause (χ2 = 748.187, p < 0.001), injury location (χ2 = 490.153, p < 0.001), fracture side (χ2 = 57.000, p < 0.001), fracture site (χ2 = 806.650, p < 0.001), associated injuries (χ2 = 322.921, p < 0.001), coma after injury (χ2 = 147.814, p < 0.001), non‐surgery‐related complications (χ2 = 7.895, p = 0.019), and surgery‐related complications (χ2 = 82.186, p < 0.001). …”
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Neuroproteomics and Systems Biology Approach to Identify Temporal Biomarker Changes Post Experimental Traumatic Brain Injury in Rats by Firas H Kobeissy, Joy D Guingab-Cagmat, Zhiqun Zhang, Ahmed Moghieb, Olena Y Glushakova, Stefania Mondello, Angela M. Boutte, John Anagli, John Anagli, Richard Rubenstein, Hisham Bahmad, Hisham Bahmad, Amy K. Wagner, Amy K. Wagner, Ronald L Hayes, Ronald L Hayes, Kevin K W Wang

“…In this work, we employed the controlled cortical impact (CCI) model of experimental TBI in rat model to assess the temporal-global proteome changes after acute (1 day) and for the first time, subacute (7 days), post-injury time frame using the established CAX-PAGE LC-MS/MS platform for protein separation combined with discrete systems biology analyses to identify temporal biomarker changes related to this rat TBI model. …”
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Injury Prevention Programmes in Male Soccer Players: An Umbrella Review of Systematic Reviews by Joel Barrera, Antonio J. Figueiredo, Filipe Manuel Clemente, Adam Field, Luis Valenzuela, Hugo Sarmento

“…Conclusions: The systematic reviews in this area suggests that prevention programs developing muscle strength and proprioception are effective in reducing the incidence and severity of injury (time out). Dynamic movements performed before a match are effective in reducing injury incidence, whilst the effects of warm-ups incorporating static stretching are unclear. …”
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Correlação entre o momento da cirurgia e a ocorrência de complicações per-operatórias no tratamento das fraturas trocanterianas do fêmur Correlation between timing of surgery and t... by Leonardo Barros Mascarenhas, João Bourbon de Albuquerque II, Rian Souza Vieira, Rodrigo Salim, Cleber Antonio Jansen Paccola, Maurício Kfuri Júnior

“…The variables taken into account were sex, age, date and mechanism of injury, time of admission, type of fracture (AO classification), pre and post-operative complica- tions, delay between trauma and surgery time, time and duration of surgery, implant used, Tip Apex Distance (TAD), and hospital stay. …”
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Vascular Cognitive Impairment and cognitive decline; a longitudinal study comparing different types of vascular brain injury - The TRACE-VCI study by Jooske MF Boomsma, Lieza G Exalto, Frederik Barkhof, Anna E Leeuwis, Niels D Prins, Philip Scheltens, Charlotte E Teunissen, Henry C Weinstein, Geert Jan Biessels, Wiesje M van der Flier, On-behalf-of-the-TRACE-VCI-study-group

“…The association of different types of vascular brain injury with cognitive decline was evaluated with linear mixed models, including one type of vascular brain injury (dichotomized), time and vascular brain injury*time, adjusted for sex, age, dementia status (yes/no), education (Verhage scale) and medial temporal lobe atrophy (MTA) score (dichotomized as ≥ 1.5). …”
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Apelin-13 Protects Neurons by Attenuating Early-Stage Postspinal Cord Injury Apoptosis In Vitro by Taotao Lin, Yujie Zhao, Shengyu Guo, Zhengru Wu, Wenwen Li, Rongcan Wu, Zhenyu Wang, Wenge Liu

“…Therefore, the OGD injury time of 6 h was used in subsequent experiments. …”
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