Mannose-binding lectin in the innate immune system / by 498718 De Messias-Reason, Iara, Boldt, Angelica B. W.

Early interactions between Trypanosoma brucei and the innate immune system by Griffiths, SR, Taylor, P, Ginger, M, Gull, K, Gordon, S

Harnessing the innate immune system for improved VLP-based immunotherapy by Cruz-Gomes, A

Harnessing the innate immune system to accelerate fracture healing in osteoporotic mice by Chan, J, Glass, G, Ersek, A, Williams, G, Freidin, A, Gowers, K, Jeffery, R, Otto, W, Poulsom, R, Feldmann, M, Rankin, S, Horwood, N, Nanchahal, J

CALHM6: function in the innate immune system and role in infectious diseases by Danielli, S

Direct activation of a bacterial innate immune system by a viral capsid protein by Zhang, Tong, Tamman, Hedvig, Coppieters ’t Wallant, Kyo, Kurata, Tatsuaki, LeRoux, Michele, Srikant, Sriram, Brodiazhenko, Tetiana, Cepauskas, Albinas, Talavera, Ariel, Martens, Chloe, Atkinson, Gemma C, Hauryliuk, Vasili, Garcia-Pino, Abel, Laub, Michael T

“…Similar to how eukaryotic innate immune systems sense foreign invaders through pathogen-associated molecular patterns<jats:sup>4</jats:sup> (PAMPs), many bacterial immune systems that respond to bacteriophage infection require phage-specific triggers to be activated. …”
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Interaction of viral capsid-derived virus-like particles (VLPs) with the innate immune system by Mohsen, M, Gomes, A, Vogel, M, Bachmann, M

“…This review discusses the interaction of viral capsid-derived VLPs with the innate immune system.…”

Destabilized adaptive influenza variants critical for innate immune system escape are potentiated by host chaperones by Phillips, Angela Marie, Ponomarenko, Anna, Butty, Vincent L G, Whittaker, Charles A., Moore, Christopher Lawrence, Shoulders, Matthew D., Chen, Kenny,Ph. D.Massachusetts Institute of Technology.

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Identification of the protein kinases that activate the E3 ubiquitin ligase Pellino 1 in the innate immune system by Goh, Eddy T. H., Arthur, J. Simon C., Cheung, Peter Ching For, Akira, Shizuo, Toth, Rachel, Cohen, Philip

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Keeping your armour intact: how HIV-1 evades detection by the innate immune system: HIV-1 capsid controls detection of reverse transcription products by the cytosolic DNA sensor cGAS. by Maelfait, J, Seiradake, E, Rehwinkel, J

Keeping your armour intact: How HIV-1 evades detection by the innate immune system: HIV-1 capsid controls detection of reverse transcription products by the cytosolic DNA sensor cGAS Prospects and Overviews J.... by Maelfait, J, Seiradake, E, Rehwinkel, J

Primer: making sense of T-cell memory. by Beverley, P

“…Pathogen-associated molecular patterns of invading organisms deliver signals to pattern-recognition receptors that activate the innate immune system. Ligation of the T-cell receptor by peptides bound to MHC antigens and presented by dendritic cells, together with signals produced by the activated innate immune system, initiate T-cell responses. …”

Neutrophil antimicrobial proteins enhance Shigella flexneri adhesion and invasion. by Eilers, B, Mayer-Scholl, A, Walker, T, Tang, C, Weinrauch, Y, Zychlinsky, A

“…Neutrophils are the first cells of the innate immune system recruited to the site of infection. …”

In vitro tests of natural allelic variation of innate immune genes (avian β-defensins) reveal functional differences in microbial inhibition. by Hellgren, O, Sheldon, B, Buckling, A

“…Functional allelic variation in the innate immune system has received little attention. Here, we investigate whether naturally occurring allelic variation within the avian innate immune system (β-defensins) is associated with variation in antimicrobial activity. …”

Association between a complex insertion/deletion polymorphism in NOD1 (CARD4) and susceptibility to inflammatory bowel disease. by McGovern, D, Hysi, P, Ahmad, T, van Heel, D, Moffatt, M, Carey, A, Cookson, W, Jewell, D

“…The identification of the role of genetic variants within NOD2 (CARD15) in Crohn's disease and ulcerative colitis susceptibility highlight the role of the innate immune system in inflammatory bowel disease (IBD) pathogenesis. …”

Convergent evolution by cancer and viruses in evading the NKG2D immune response by Baugh, R, Khalique, H, Seymour, LW

“…The natural killer group 2 member D (NKG2D) receptor and its family of NKG2D ligands (NKG2DLs) are key components in the innate immune system, triggering NK, γδ and CD8+ T cell-mediated immune responses. …”

Genome-to-genome analysis highlights the effect of the human innate and adaptive immune systems on the hepatitis C virus by Ansari, M, Pedergnana, V, Ip, C, Magri, A, Von Delft, A, Bonsall, D, Chaturvedi, N, Bartha, I, Smith, D, Nicholson, G, McVean, G, Trebes, A, Piazza, P, Fellay, J, Cooke, G, Foster, G, STOP-HCV Consortium, Hudson, E, McLauchlan, J, Simmonds, P, Bowden, R, Klenerman, P, Barnes, E, Spencer, C

“…These findings highlight the interplay between the innate immune system and the viral genome in HCV control.…”

Advances in Neutrophil Testing In Type 2 Diabetes Mellitus by Tay, Hui Min, Hou, Han Wei, Dalan, Rinkoo, Boehm, Bernhard Otto

“…Patients with type 2 diabetes mellitus (T2DM) suffer from impaired glucose metabolism which results in low-grade inflammation and activation of the innate immune system. Neutrophils the key effector cells of the innate immune system and heavily implicated in the pathogenesis of T2DM, are promising cell-based inflammatory biomarkers for immune health profiling, provided that they can be rapidly purified and measured with sufficient precision. …”
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No compensatory relationship between the innate and adaptive immune system in wild-living European badgers by Sin, Y, Newman, C, Dugdale, H, Buesching, C, Mannarelli, M, Annavi, G, Burke, T, Macdonald, D

“…The innate immune system provides the primary vertebrate defence system against pathogen invasion, but it is energetically costly and can have immune pathological effects. …”

Macrophage pattern recognition receptors in immunity, homeostasis and self tolerance. by Mukhopadhyay, S, Plüddemann, A, Gordon, S

“…In the light of present knowledge ofmacrophage surface antigens, we discuss self versus nonself recognition, microbicidal effector functions and self tolerance in the innate immune system.…”