Clutching at Guidance Cues: The Integrin–FAK Axis Steers Axon Outgrowth by Mathew Davis-Lunn, Benjamin T. Goult, Melissa R. Andrews

Subjects: “…integrin…”
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Fibronectin Regulation of Integrin B1 and SLUG in Circulating Tumor Cells by Jeannette Huaman, Michelle Naidoo, Xingxing Zang, Olorunseun O. Ogunwobi

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The Interplay between Integrins and Immune Cells as a Regulator in Cancer Immunology by Qingfang Zhang, Shuo Zhang, Jianrui Chen, Zhenzhen Xie

Subjects: “…integrins…”
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Role of Integrins in Resistance to Therapies Targeting Growth Factor Receptors in Cancer by Elisabete Cruz da Silva, Monique Dontenwill, Laurence Choulier, Maxime Lehmann

Subjects: “…integrin…”
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Integrin Signaling in the Central Nervous System in Animals and Human Brain Diseases by Hiroko Ikeshima-Kataoka, Chikatoshi Sugimoto, Tatsuya Tsubokawa

“…The integrin family is involved in various biological functions, including cell proliferation, differentiation and migration, and also in the pathogenesis of disease. …”
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Roles of Integrin in Cardiovascular Diseases: From Basic Research to Clinical Implications by Shuo Zhang, Qingfang Zhang, Yutong Lu, Jianrui Chen, Jinkai Liu, Zhuohan Li, Zhenzhen Xie

Subjects: “…integrins…”
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Mast Cell Protease 7 Promotes Angiogenesis by Degradation of Integrin Subunits by Devandir A. de Souza Junior, Carolina Santana, Gabriel V. Vieira, Constance Oliver, Maria Celia Jamur

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Regulation of trophoblast beta1-integrin expression by contact with endothelial cells by Thirkill Twanda L, Hendren Sonia R, Soghomonians Arlen, Mariano Natalie F, Barakat Abdul I, Douglas Gordon C

“…Trophoblast β1 integrin expression (assessed by immunofluorescence microscopy and Western blotting) was increased when PECAM-1 or αVβ3 integrin, but not ICAM-1, was used as substrate.…”
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Integrin-Linked Kinase Is a Novel Therapeutic Target in Ovarian Cancer by Michael A. Ulm, Tiffany M. Redfern, Ben R. Wilson, Suriyan Ponnusamy, Sarah Asemota, Patrick W. Blackburn, Yinan Wang, Adam C. ElNaggar, Ramesh Narayanan

Subjects: “…integrin-linked kinase (ILK)…”
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Alpha 5 Integrin Mediates Osteoarthritic Changes in Mouse Knee Joints by Candela, Maria Elena, Gunawardena, Aruni T., Zhang, Kairui, Cantley, Leslie, Yasuhara, Rika, Usami, Yu, Francois, Noelle, Iwamoto, Masahiro, van der Flier, Arjan, Zhang, Yejia, Qin, Ling, Enomoto-Iwamoto, Motomi, Wang, Chao, 1972-, Han, Lin, Ph. D. Massachusetts Institute of Technology

“…We hypothesized that α5 integrin signaling is involved in pathogenesis of OA. …”
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Integrin-targeted cancer immunotherapy elicits protective adaptive immune responses by Dranoff, Glenn, Kwan, Byron Hua, Zhu, Eric Franklin, Tzeng, Alice, Sugito, Harun R., Eltahir, Ahmed A., Ma, Botong, Delaney, Mary K., Murphy, Patrick A., Kauke, Monique Jacqueline, Angelini, Alessandro, Momin, Noor, Mehta, Naveen, Maragh, Alecia M., Hynes, Richard O., Cochran, Jennifer R., Wittrup, Karl Dane

“…Certain RGD-binding integrins are required for cell adhesion, migration, and proliferation and are overexpressed in most tumors, making them attractive therapeutic targets. …”
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Elucidation of the Roles of Tumor Integrin  1 in the Extravasation Stage of the Metastasis Cascade by Chen, Michelle B., Lamar, John, Li, Ran, Hynes, Richard O., Kamm, Roger Dale

“…Tumor integrin β1 (ITGB1) contributes to primary tumor growth and metastasis, but its specific roles in extravasation have not yet been clearly elucidated. …”
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Cell shape & integrins : determinants of extracellular matrix regulation of growth & survival by Chen, Christopher S. (Christopher Sao Bing)

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Standing on the shoulders of giant : small membrane molecules that associate laterally with integrins. by Wong, Alvin Yao Sheng.

“…A mode of integrins modulation is lately gaining acceptance and increasingly studied is: how the type of adhesion and signalling following integrins ligation may be modulated by lateral association with other membrane molecules.This review paper will elaborate more on some of these components that interact laterally with integrins and provide modulatory function. …”
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Structure-function analysis of ß2 integrins using monoclonal antibodies. by Foo, Adeline Shen Yun.

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Structural features that affect β2 integrin expression and regulation of adhesion by Guan, Siyu

“…A hallmark for the Leukocyte Adhesion Deficiency 1 (LAD-1) syndrome is the defect in the β2 integrins due to mutations in the ITGB2 gene. To establish the correlation between LAD-1 genotype and phenotype, as well as better understand integrin function and structure, 19 LAD-1 missense mutants that recently identified were introduced into the pcDNA3 plasmid containing the ITGB2 cDNA. …”
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Mapping interactions of filamin and migfilin : mechanism of inside-out signaling integrins. by Lu, Lewis Zhiping.

“…Integrin is a transmembrane heterodimer receptor that facilitates the connection of a cell to its environment. …”
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Characterization of structures and interactions of beta 2 integrin tail with cytosolic proteins by Lu, Lewis Zhiping

“…Integrins are important transmembrane proteins that facilitate many vital processes in humans such as development, immune responses and blood clotting. …”
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BK ablation attenuates osteoblast bone formation via integrin pathway by Wang, Y, Guo, Q, Hei, H, Tao, J, Zhou, Y, Dong, J, Xin, H, Cai, H, Gao, J, Yu, K, Reilly, S, Yin, P, Zhang, X

“…Mechanistically, BK ablation in bone and bone marrow mesenchymal stem cells (BMSCs) of BKO mice inhibited integrin signaling. Furthermore, the binding of α subunit of BK with integrin β1 protein in osteoblasts was confirmed, and FAK-ERK1/2 signaling was proved to be involved by genetic modification of KCNMA1 (which encodes the α subunit of BK) in ROS17/2.8 osteoblast cells. …”

Transmembrane and cytoplasmic domains in integrin activation and protein-protein interactions (review). by Wegener, K, Campbell, I

“…Integrins are heterodimeric membrane-spanning adhesion receptors that are essential for a wide range of biological functions. …”