Association between Decreased ITGA7 Levels and Increased Muscle α-Synuclein in an MPTP-Induced Mouse Model of Parkinson’s Disease by Sangeun Han, Sabina Lim, Sujung Yeo

“…Herein, we investigated the potential relationship between integrin α7 (<i>ITGA7</i>) and α-synuclein (α-syn) in the muscle of methyl-4-phenyl-1,2,3,6 tetrahydropyridine (MPTP)-induced mice and C2C12 cells. …”
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Recent Advances in Stem Cell Differentiation Control Using Drug Delivery Systems Based on Porous Functional Materials by Yun-Sik Eom, Joon-Ha Park, Tae-Hyung Kim

“…Ongoing research has sought to induce stem cell differentiation using diverse differentiation factors, including chemicals, proteins, and integrin expression. These differentiation factors play a pivotal role in a variety of applications. …”
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Tamoxifen-resistant breast cancer cells exhibit reactivity with Wisteria floribunda agglutinin. by May Thinzar Hlaing, Yoshiya Horimoto, Kaori Denda-Nagai, Haruhiko Fujihira, Miki Noji, Hiroyuki Kaji, Azusa Tomioka, Yumiko Ishizuka, Harumi Saeki, Atsushi Arakawa, Mitsue Saito, Tatsuro Irimura

“…Glycoproteins seemed to be responsible for the differential WFA binding and the results of mass spectrometry revealed several membrane glycoproteins, such as CD166 and integrin beta-1, as candidates contributing to increased WFA binding. …”
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The Role of the Ectopeptidase APN/CD13 in Cancer by Uwe Lendeckel, Farzaneh Karimi, Ruba Al Abdulla, Carmen Wolke

“…APN/CD13-regulated signaling pathways include integrin recycling, the regulation of small GTPase activities, cell–ECM interactions, and Erk1/2, PI3K, and Wnt signaling. …”
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Luteolin inhibits GPVI-mediated platelet activation, oxidative stress, and thrombosis by Yujia Ye, Lihong Yang, Min Leng, Qian Wang, Jiankui Wu, Wen Wan, Huawei Wang, Longjun Li, Yunzhu Peng, Shengjie Chai, Zhaohui Meng

“…Surface plasmon resonance showed that luteolin bonded GPVI. Luteolin inhibited integrin αIIbβ3-mediated platelet activation. Luteolin inhibited mesenteric artery thrombosis and collagen- adrenergic-induced pulmonary thrombosis in mice. …”
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CD47 as a Potential Target to Therapy for Infectious Diseases by Lamin B. Cham, Tom Adomati, Fanghui Li, Murtaza Ali, Karl S. Lang

“…The integrin associated protein (CD47) is a widely and moderately expressed glycoprotein in all healthy cells. …”
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Differential innate immune response of endometrial cells to porcine reproductive and respiratory syndrome virus type 1 versus type 2 by Muttarin Lothong, Dran Rukarcheep, Suphot Wattanaphansak, Sumpun Thammacharoen, Chatsri Deachapunya, Sutthasinee Poonyachoti

“…PRRSV mediator proteins, CD151, CD163, sialoadhesin (Sn), integrin and vimentin, were upregulated following type 1 and type 2 infection. …”
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Apolipoprotein Signature of HDL and LDL from Atherosclerotic Patients in Relation with Carotid Plaque Typology: A Preliminary Report by Francesco Finamore, Gabriele Nieddu, Silvia Rocchiccioli, Rita Spirito, Anna Guarino, Marilena Formato, Antonio Junior Lepedda

“…By this approach, two proteins with potential implications in inflammatory, immune, and hemostatic pathways, namely, integrin beta-2 (P05107) and secretoglobin family 3A member 2 (Q96PL1), have been confirmed to belong to the HDL proteome. …”
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Biodegradable small-diameter vascular graft: types of modification with bioactive molecules and RGD peptides by E. A. Senokosova, E. O. Krivkina, L. V. Antonova, L. S. Barbarash

“…This sequence is present in most extracellular matrix proteins and has a tropism for integrin receptors of endothelial cells. Many studies have shown that imitation of the functional activity of the natural extracellular matrix can promote spontaneous endothelization of the inner surface of a vascular graft. …”
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Tenascin-X as a causal gene for classical-like Ehlers-Danlos syndrome by Emiko Okuda-Ashitaka, Ken-ichi Matsumoto

“…We address the molecular mechanism for the induction of COL1A1 by the expression of both a peptide derived from the fibrinogen-related domain of TNX and integrin α11.…”
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Daidzein Inhibits Human Platelet Activation by Downregulating Thromboxane A₂ Production and Granule Release, Regardless of COX-1 Activity by Hyun-Jin Hong, Gi-Suk Nam, Kyung-Soo Nam

“…These results suggest that daidzein inhibits granule release (ATP, serotonin, P-selectin), integrin α_IIbβ₃ activation, and clot retraction. …”
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Recurrent Multidrug-Resistant <i>Clostridium difficile</i> Infection Secondary to Ulcerative Colitis a Case Report by Arturo P. Jaramillo, Javier Castells, Sabina Ibrahimli, Steven Siegel

“…In this case report, we demonstrated mdCDI in a young woman after treatment with multiple drug therapies as well as with semi-invasive procedures as follows: antibiotics (vancomycin, fidaxomicin), anti-inflammatory agents (mesalamine, sulfasalazine), corticosteroids (budesonide, prednisone), integrin receptor antagonists (vedolizumab), several semi-invasive procedures such as fecal transplant microbiota (FMT), aminosalicylates (5-ASA), treatment with tumor necrosis factor (TNF) blockers (adalimumab, golimumab), and immunomodulators (upadcitinib, tofacitinib). …”
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Relationship between Tumor Budding and Partial Epithelial–Mesenchymal Transition in Head and Neck Cancer by Kohei Okuyama, Keiji Suzuki, Souichi Yanamoto

“…Herein, we review the current understanding of p-EMT and TME dynamics and discuss the relationship between TB development and p-EMT, focusing on CAFs, hypoxia, tumor-associated macrophages, laminin–integrin crosstalk, membrane stiffness, enzymes, and viral infections in cancers, and clarify the gap of evidence between HNSCC and CRC.…”
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Tumor-Targeted Fluorescent Proteinoid Nanocapsules Encapsulating Synergistic Drugs for Personalized Cancer Therapy by Ella Itzhaki, Elad Hadad, Neta Moskovits, Salomon M. Stemmer, Shlomo Margel

“…The arginine-glycine-glutamic acid (RGD) sequence is known for its preferential attraction to αvβ3 integrin, which is highly expressed on neovascular endothelial cells that support tumor growth. …”
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Biomolecules Involved in Both Metastasis and Placenta Accreta Spectrum—Does the Common Pathophysiological Pathway Exist? by Anna K. Rekowska, Karolina Obuchowska, Magdalena Bartosik, Żaneta Kimber-Trojnar, Magdalena Słodzińska, Magdalena Wierzchowska-Opoka, Bożena Leszczyńska-Gorzelak

“…This article presents a review of molecular biomarkers involved in both the microenvironment of tumors and placental cells, including placental growth factor (PlGF), vascular endothelial growth factor (VEGF), E-cadherin (CDH1), laminin γ2 (LAMC2), the zinc finger E-box-binding homeobox (ZEB) proteins, αVβ3 integrin, transforming growth factor β (TGF-β), β-catenin, cofilin-1 (CFL-1), and interleukin-35 (IL-35). …”
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Dysregulated Signalling Pathways Driving Anticancer Drug Resistance by Nauf Bou Antoun, Athina-Myrto Chioni

“…Moreover, transforming growth factor-beta (TGF-β), Notch, epidermal growth factor receptor (EGFR), integrin-extracellular matrix (ECM), nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB), phosphoinositol-3-kinase/protein kinase B/mammalian target of rapamycin (PI3K/Akt/mTOR), wingless-related integration site (Wnt/β-catenin), Janus kinase/signal transducers and activators of transcription (JAK/STAT) and RAS/RAF/mitogen-activated protein kinase (MAPK) signalling pathways are some of the key players that have a pivotal role in drug resistance mechanisms. …”
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The Neural Progenitor Cell-Associated Transcription Factor FoxG1 Regulates Cardiac Epicardial Cell Proliferation by Lucy Pilcher, Lara Solomon, Julie A. Dragon, Dhananjay Gupta, Jeffrey L. Spees

“…To obtain epicardial cells, we enzymatically digested the surfaces of whole hearts and performed magnetic-activated cell sorting (MACS) with antibodies against CD104 (integrin β4). By cDNA microarray assays, we identified genes with increased transcription in epicardial cells after running exercise; these included FoxG1, a transcription factor that controls neural progenitor cell proliferation during brain development and Snord116, a small noncoding RNA that coordinates expression of genes with epigenetic, circadian, and metabolic functions. …”
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CD34+ cells represent highly functional endothelial progenitor cells in murine bone marrow. by Junjie Yang, Masaaki Ii, Naosuke Kamei, Cantas Alev, Sang-Mo Kwon, Atsuhiko Kawamoto, Hiroshi Akimaru, Haruchika Masuda, Yoshiki Sawa, Takayuki Asahara

“…Furthermore, a dramatic increase in immediate recruitment of cells to the myocardium following myocardial infarction and systemic cell injection was observed for CD34(+) cells comparing with others, which could be explained by the highest mRNA expression levels of key homing-related molecules Integrin β2 and CXCR4 in CD34(+) cells. Cell retention and incorporation into the vasculature of the ischemic myocardium was also markedly increased in the CD34(+) cell-injected group, giving a possible explanation for significant reduction in fibrosis area, significant increase in neovascularization and the best cardiac functional recovery in this group in comparison with the others. …”
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ITGB5 mutation discovered in a Chinese family with blepharophimosis-ptosis-epicanthus inversus syndrome by Cheng Tianling, Yuan Xiaobin, Yuan Shaopeng, Zhu Jianying, Tang Shengjian, Zhang Yujie

“…Using whole-exome sequence analysis, we discovered another possible mutational cause of BPES in integrin subunit beta 5 (ITGB5). The ITGB5 mutation (c.608T>C, p.Ile203Thr) appears in the base sequence of all BPES+ patients in this family, and it appears to be a three-generation-inherited mutation. …”
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The roles of HMGB1 related angiogenesis and lymphangiogenesis in oral cancer by Hiroki Kuniyasu, Tomonori Sasahira, Ujjal K. Bhawal, Yoshitomo Chihara, Miyako Kurihara, Kazuhiko Yamamoto, Tadaaki Kirita

“…MIA upregulates expression of VEGF-C and VEGF-D via p38 phosphorylation by integrin activation. Then HMGB1 and MIA is associated with lymphangiogenesis. …”
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