Integrin α7 Mutations Are Associated With Adult‐Onset Cardiac Dysfunction in Humans and Mice by Enrico Bugiardini, Andreia M. Nunes, Ariany Oliveira‐Santos, Marisela Dagda, Tatiana M. Fontelonga, Pamela Barraza‐Flores, Alan M. Pittman, Jasper M. Morrow, Matthew Parton, Henry Houlden, Perry M. Elliott, Petros Syrris, Roderick P. Maas, Mohammed M. Akhtar, Benno Küsters, Joost Raaphorst, Meyke Schouten, Erik‐Jan Kamsteeg, Baziel van Engelen, Michael G. Hanna, Rahul Phadke, Luis R. Lopes, Emma Matthews, Dean J. Burkin

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IPP Complex Reinforces Adhesion by Relaying Tension-Dependent Signals to Inhibit Integrin Turnover by Katerina M. Vakaloglou, Georgios Chrysanthis, Maria Anna Rapsomaniki, Zoi Lygerou, Christos G. Zervas

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Perspective of αβ-Integrin Imaging for Clinical Management of Pancreatic Carcinoma and Its Precursor Lesions by Katja Steiger PhD, Anna-Melissa Schlitter MD, Wilko Weichert MD, Irene Esposito MD, Hans-Jürgen Wester MD, Johannes Notni PhD

“…ß 6 -integrin immunohistochemistry analysis of a large number of pancreatic ductal adenocarcinoma (PDAC, 383 primary tumors, 7 lymph node, and 8 distant metastases) and 34 pancreatic intraepithelial neoplasia (PanIN) specimens revealed a high prevalence of α v ß 6 -integrin expression in PDAC primaries (88%) and in almost all metastases, as well as in PanIN (57%). …”
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Biphasic α2β1 Integrin Expression in Breast Cancer Metastasis to Bone by Milene N.O. Moritz, Alyssa R. Merkel, Ean G. Feldman, Heloisa S. Selistre-de-Araujo, Julie A. Rhoades (Sterling)

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Integrins control epithelial stem cell proliferation in the Drosophila ovary by modulating the Notch pathway by Lourdes Rincón-Ortega, Andrea Valencia-Expósito, Anna Kabanova, Acaimo González-Reyes, Maria D. Martin-Bermudo

Subjects: “…integrin…”
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Regulation of Renin Expression by Β1-Integrin in As4.1 Juxtaglomerular Line Cells by Nobumichi Saito, Masao Toyoda, Masumi Kondo, Makiko Abe, Noriyuki Sanechika, Moritsugu Kimura, Kaichiro Sawada, Masafumi Fukagawa

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The association and clinicopathological significance of Integrin alphavbeta6 and Rac1 expression in gastric carcinoma by Junjian Yu, Wenyu Jia, Qi Liu, Antai Yuan, Zhuoyu Jia, YuQi Sun, Zequn Li, Shougen Cao

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TMEM182 interacts with integrin beta 1 and regulates myoblast differentiation and muscle regeneration by Wen Luo, Zetong Lin, Jiahui Chen, Genghua Chen, Siyu Zhang, Manqing Liu, Hongmei Li, Danlin He, Shaodong Liang, Qingbin Luo, Dexiang Zhang, Qinghua Nie, Xiquan Zhang

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Integrin α9β1 deficiency does not impact the development of atherosclerosis in mice by In-Hyuk Jung, Nathan O. Stitziel

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Reciprocal discoidin domain receptor signaling strengthens integrin adhesion to connect adjacent tissues by Kieop Park, Ranjay Jayadev, Sara G Payne, Isabel W Kenny-Ganzert, Qiuyi Chi, Daniel S Costa, William Ramos-Lewis, Siddharthan B Thendral, David R Sherwood

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Adaptation of cell spreading to varying fibronectin densities and topographies is facilitated by β1 integrins by Enrico Domenico Lemma, Zhongxiang Jiang, Franziska Klein, Franziska Klein, Tanja Landmann, Kai Weißenbruch, Sarah Bertels, Marc Hippler, Marc Hippler, Bernhard Wehrle-Haller, Martin Bastmeyer, Martin Bastmeyer

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Integrin-β6 Serves as a Potential Prognostic Serum Biomarker for Gastric Cancer by Zequn Li, Yuqi Sun, Jianfei Xu, Hao Yang, Xiaodong Liu, Yulong Tian, Shougen Cao, Yanbing Zhou

“…Discovering novel biomarkers that easily accessed is a key step towards the personalized medicine approach for gastric cancer patients. Integrin-β6 (ITGB6) is a subtype of integrin that is exclusively expressed on the surface of epithelial cells and is up-regulated in various tumors. …”
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The LINC complex transmits integrin-dependent tension to the nuclear lamina and represses epidermal differentiation by Emma Carley, Rachel M Stewart, Abigail Zieman, Iman Jalilian, Diane E King, Amanda Zubek, Samantha Lin, Valerie Horsley, Megan C King

“…Using a molecular biosensor, we find that tension on the nucleus through linker of nucleoskeleton and cytoskeleton (LINC) complexes requires integrin engagement in undifferentiated epidermal stem cells and is released during differentiation concomitant with decreased tension on A-type lamins. …”
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Mechanically active integrins target lytic secretion at the immune synapse to facilitate cellular cytotoxicity by Mitchell S. Wang, Yuesong Hu, Elisa E. Sanchez, Xihe Xie, Nathan H. Roy, Miguel de Jesus, Benjamin Y. Winer, Elizabeth A. Zale, Weiyang Jin, Chirag Sachar, Joanne H. Lee, Yeonsun Hong, Minsoo Kim, Lance C. Kam, Khalid Salaita, Morgan Huse

“…We thus conclude that lymphocytes employ an integrin-dependent mechanical checkpoint to enhance their cytotoxic power and fidelity.…”
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Pseudomonas aeruginosa PilY1 binds integrin in an RGD- and calcium-dependent manner. by Michael D L Johnson, Christopher K Garrett, Jennifer E Bond, Kimberly A Coggan, Matthew C Wolfgang, Matthew R Redinbo

“…Eliminating calcium binding from this site using a D608A mutation abolished integrin binding; in contrast, a calcium binding mimic (D608K) preserved integrin binding. …”
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Relationship of the integrin profile of the primary tumor to metastasis to regional lymph nodes in breast cancer by Marina V. Zavyalova, Gleb A. Kuznecov, Evgeniya S. Grigoryeva, Liubov A. Tashireva, Dmitry S. Pismenny, Vladimir M. Perelmuter

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Bordetella adenylate cyclase toxin is a unique ligand of the integrin complement receptor 3 by Radim Osicka, Adriana Osickova, Shakir Hasan, Ladislav Bumba, Jiri Cerny, Peter Sebo

“…Integrins are heterodimeric cell surface adhesion and signaling receptors that are essential for metazoan existence. …”
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New insights into regulation of αIIbβ3 integrin signaling by filamin A by Lamia Lamrani, Frédéric Adam, Christelle Soukaseum, Cécile V. Denis, Hana Raslova, Jean‐Philippe Rosa, Marijke Bryckaert

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Semaphorin 7A is protective during inflammatory peritonitis through integrin receptor signaling by Andreas Körner, David Köhler, Mariella Schneider, Judith M. Roth, Tiago F. Granja, Claudia Eggstein, Valbona Mirakaj, Peter Rosenberger

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Interplay between integrins and cadherins to control bone differentiation upon BMP-2 stimulation by Anne Valat, Laure Fourel, Adria Sales, Paul Machillot, Paul Machillot, Anne-Pascale Bouin, Carole Fournier, Lauriane Bosc, Mélanie Arboléas, Ingrid Bourrin-Reynard, Amy J. Wagoner Johnson, Amy J. Wagoner Johnson, Amy J. Wagoner Johnson, Amy J. Wagoner Johnson, Franz Bruckert, Corinne Albigès-Rizo, Catherine Picart, Catherine Picart, Catherine Picart

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