RELA∙8-Oxoguanine DNA Glycosylase1 Is an Epigenetic Regulatory Complex Coordinating the Hexosamine Biosynthetic Pathway in RSV Infection by Xiaofang Xu, Dianhua Qiao, Lang Pan, Istvan Boldogh, Yingxin Zhao, Allan R. Brasier

“…We conclude that the RELA∙OGG1 complex is an epigenetic regulator mediating metabolic reprogramming and N glycoprotein modifications of integrins in response to RSV. These findings have implications for viral-induced adaptive epithelial responses.…”
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COL12A1-rs970547, Mutant Allele Advantage by Being Protective against Recurrent Spontaneous Abortion by Abasalt Hosseinzadeh Colagar, Mohammadmahdi Arjmand, Mohammadkazem Heydari, Gholam Ali Jorsaraei

“…Moreover, 3D structures investigation indicated that COL12A1-rs970547 may affect the structure of COL12A1 and its interaction with Integrins. The analysis of the signaling pathway and proteins’ physical interaction network also revealed the interaction of COL12A1 and CD44 with MMP2 and MMP9. …”
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Changes in extracellular matrix (ECM) and ECM-associated proteins in the metastatic progression of prostate cancer by Sikes Robert A, Cooper Carlton R, Stewart Delisha A

“…These will be discussed within the context of changes in expression and functional heterodimerization patterns of integrins, changes in ECM expression and reorganization by proteases facilitating invasion. …”
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Human eosinophil-lymphocyte interactions by Weller Peter F, Lim Kaiser

“…Eosinophils share with CD4+ lymphocytes expression of a number of receptors, including CD4 and IL-2R, and specific alpha4 integrins that may help in their common recruitment and activation. …”
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Discoidin domain receptors; an ancient family of collagen receptors has major roles in bone development, regeneration and metabolism by Renny T. Franceschi, Shawn A. Hallett, Chunxi Ge

“…For many years, specific β1 integrins were considered the main collagen receptors in bone, but, more recently, the important role of a second, more primordial collagen receptor family, the discoidin domain receptors, has become apparent. …”
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Galectin functions in cancer-associated inflammation and thrombosis by Linus Kruk, Linus Kruk, Attila Braun, Erika Cosset, Thomas Gudermann, Thomas Gudermann, Elmina Mammadova-Bach, Elmina Mammadova-Bach

“…Recent studies described that different isoforms of galectins can induce platelet adhesion, aggregation, and granule release through the interaction with platelet-specific glycoproteins and integrins. Patients with cancer and/or deep-venous thrombosis have increased levels of galectins in the vasculature, suggesting that these proteins could be important contributors to cancer-associated inflammation and thrombosis. …”
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Pannus growth regulators as potential targets for biological therapy in rheumatoid arthritis by A. S. Mikhaylova, O. M. Lesnyak

“…It is  shown that the most promising targets for biological therapy may be FLS adhesion molecules, such as transmembrane receptor cadherin  11, integrins α5/β1, and VCAM1, ICAM1, which actively participate in the attachment of FLSs to the cartilage surface and activate their production of cytokines, growth factors and aggression factors.…”
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Role of LFA-1 and ICAM-1 in Cancer by Manuel Reina, Enric Espel

“…The lymphocyte function-associated antigen-1 (LFA-1) (also known as CD11a/CD18 and αLβ2), is just one of many integrins in the human body, but its significance is derived from its exclusive presence in leukocytes. …”
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Extracellular Vesicles as Next-Generation Biomarkers in Lung Cancer Patients: A Case Report on Adenocarcinoma and Squamous Cell Carcinoma by Monika Ruzycka-Ayoush, Monika Prochorec-Sobieszek, Andrzej Cieszanowski, Maciej Glogowski, Anna Szumera-Cieckiewicz, Joanna Podgorska, Alicja Targonska, Kamil Sobczak, Grazyna Mosieniak, Ireneusz P. Grudzinski

“…All the collected EVs expressed canonical tetraspanins (CD9, CD63, and CD81) highly coexpressed with molecules such as lysosome-associated membrane protein-1 (LAMP1–CD107a), sialomucin core protein 24 (CD164), Raph blood group (CD151), and integrins (ITGB1 and ITGA2). This representation of the protein molecules on the EV surface may provide valuable information on NSCLC subtypes and offer new diagnostic opportunities as next-generation biomarkers in personalized oncology.…”
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Platelet-derived microparticles stimulate the invasiveness of colorectal cancer cells via the p38MAPK-MMP-2/MMP-9 axis by Hassan Kassassir, Izabela Papiewska-Pająk, Jakub Kryczka, Joanna Boncela, M. Anna Kowalska

“…Moreover, PMPs could transfer platelet-specific integrins and stimulate the expression of integrins already present on tested cell lines. …”
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Modeling cell contractility responses to acoustic tweezing cytometry by Suyan Zhang, Zhenzhen Fan

“…Targeted microbubbles, which are attached to integrins and subsequently the actin cytoskeleton, anchor, amplify and transmit the mechanical energy in an acoustic field inside the cells, eliciting prominent cytoskeleton contractile force increases in various cell types. …”
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Indentation of Anisotropic Tissue Using a Three-Dimensional Mechanical Bidomain Model by Dilmini Wijesinghe, Bradley J. Roth

“…The mechanical bidomain model hypothesizes that the relative displacement between intra- and extracellular spaces triggers a force on the mechanosensitive proteins in the membrane: integrins. Some soft tissues, such as cardiac muscle, are anisotropic, a property which arises from the fibrous structure of the tissue. …”
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The molecular regulation of oligodendrocyte development and CNS myelination by ECM proteins by Momona Yamada, Miho Iwase, Binri Sasaki, Nobuharu Suzuki

“…The activities of these ECM proteins are exerted through binding to the cellular receptors and co-receptors, such as integrins and growth factor receptors, which induces the signaling to form the elaborated and functional structure of myelin. …”
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Solid phase synthesis and thioether ligation of hairpin peptides from single-pass transmembrane receptors. by Surya, Wahyu.

“…Integrins and fibroblast growth factor receptors (FGFR) are important members of single-pass transmembrane receptors. …”
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The interaction of macrophage receptors with bacterial ligands. by Plüddemann, A, Mukhopadhyay, S, Gordon, S

“…These receptors include scavenger receptors, C-type lectins, integrins, Toll-like receptors and siglecs. The bacterial ligands generally recognised by these receptors range from lipopolysaccharides on Gram-negative bacteria to peptidoglycan and lipoteichoic acid on Gram-positive bacteria. …”

Expression of cell adhesion molecules in oesophageal carcinoma and its prognostic value. by Nair, K, Naidoo, R, Chetty, R

“…This review provides a brief description of five families of CAMs (cadherins, integrins, CD44, immunoglobulin superfamily, and selectins) and highlights their altered expression in relation both to prognosis and tumour behaviour in squamous cell carcinoma and adenocarcinoma of the oesophagus.…”

Interfering with leukocyte trafficking in Crohn's disease by Biswas, S, Bryant, R, Travis, S

“…Drugs target the interaction between lymphocytes and endothelial cells via integrins and their ligand cellular adhesion molecules. …”

Are cellular mechanosensors potential therapeutic targets in osteoarthritis? by Drexler, S, Wann, A, Vincent, T

“…Here, we review those pathways with demonstrable roles in chondrocyte mechanotransduction including ion channels, integrins, the primary cilium and the pericellular and intracellular matrices. …”

Revolutionizing anti-tumor therapy: unleashing the potential of B cell-derived exosomes by Jingwen Xiong, Hao Chi, Guanhu Yang, Songyun Zhao, Jing Zhang, Lisa Jia Tran, Zhijia Xia, Fang Yang, Gang Tian

“…Exosome research is an important development in cancer research, as they have been shown to carry various molecules such as major histocompatibility complex(MHC) molecules and integrins, which regulate the TME. Given the close association between TME and cancer development, targeting substances within the TME has emerged as a promising strategy for cancer therapy. …”
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Drug-Induced Gingival Overgrowth—Molecular Aspects of Drug Actions by Agnieszka Droździk, Marek Droździk

“…Dysregulation of collagenase activity, as well as integrins and membrane receptors, are key mechanisms of reduced degradation or excessive synthesis of connective tissue components. …”
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