Specificity of the VP1 GH loop of Foot-and-Mouth Disease virus for alphav integrins. by Burman, A, Clark, S, Abrescia, N, Fry, E, Stuart, D, Jackson, T

“…Foot-and-mouth disease virus (FMDV) can use a number of integrins as receptors to initiate infection. Attachment to the integrin is mediated by a highly conserved arginine-glycine-aspartic acid (RGD) tripeptide located on the GH loop of VP1. …”

The structure of the talin/integrin complex at a lipid bilayer: an NMR and MD simulation study. by Kalli, A, Wegener, K, Goult, B, Anthis, N, Campbell, I, Sansom, MS

“…Integrins are cell surface receptors crucial for cell migration and adhesion. …”

Paracrine costimulation of IFN-γ signaling by integrins modulates CD8 T cell differentiation by Krummel, MF, Mahale, J, Uhl, LF, Mazet, J, Mujal, A, Hardison, E, Weber, R, Gartner, Z, Gerard, A

“…This is driven by IFN-γ costimulation by integrins at T-T synapses, and leads to synergistic phosphorylation of the proximal STAT1 molecule and accelerated IL-2 receptor down-regulation. …”

The Multifaceted Roles of EGFL7 in Cancer and Drug Resistance by Beate Heissig, Yousef Salama, Satoshi Takahashi, Ko Okumura, Koichi Hattori

Subjects: “…beta 3 integrin…”
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Immunohistochemical evaluation for integrin binding sialoprotein on healing process of intrabony defect treated by bone sialoprotein by Mayada K. Jaafar, Enas F Kadhim

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RIAM-VASP Module Relays Integrin Complement Receptors in Outside-In Signaling Driving Particle Engulfment by Alvaro Torres-Gomez, Jose Luis Sanchez-Trincado, Víctor Toribio, Raul Torres-Ruiz, Sandra Rodríguez-Perales, María Yáñez-Mó, Pedro A. Reche, Carlos Cabañas, Esther M. Lafuente

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Polymorphism in Integrin ITGA2 is Associated with Ischemic Stroke and Altered Serum Cholesterol in Chinese Individuals by Jian-Xia Lu, Zhong-Qian Lu, Wan-Xiang Wang, Shao-lan Zhang, Juan Zhi, Zheng-Ping Chen

Subjects: “…Integrin α2…”
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Low Stability of Integrin-Binding Deficient Mutant of FGF1 Restricts Its Biological Activity by Anna Szlachcic, Martyna Sochacka, Aleksandra Czyrek, Lukasz Opalinski, Daniel Krowarsch, Jacek Otlewski, Malgorzata Zakrzewska

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β1-Integrin blockade prevents podocyte injury in experimental models of minimal change disease by Gabriel Cara-Fuentes, Rakesh Verma, Madhusudan Venkatareddy, Colin Bauer, Federica Piani, Sogut Turkmen Aksoy, Neha Vazzalwar, Gabriela E. Garcia, Mindy Banks, Flor A. Ordoñez, Carmen de Lucas-Collantes, Petter Bjornstad, Juan D. González Rodríguez, Richard J. Johnson, Puneet Garg

“…Here, we tested whether podocyte β1 integrin is the upstream modulator of FAK activation and podocyte injury in experimental models of MCD-like injury. …”
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Association of integrin-β2 polymorphism and expression with the risk of rheumatoid arthritis and osteoarthritis in Egyptian patients by Aliaa M. Selim, Yumn A. Elsabagh, Maha M. El-Sawalhi, Nabila A. Ismail, Mahmoud A. Senousy

Subjects: “…Integrins…”
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The Potential of Extracellular Matrix- and Integrin Adhesion Complex-Related Molecules for Prostate Cancer Biomarker Discovery by Ivana Samaržija

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Vascular tissue reconstruction by monocyte subpopulations on small-diameter acellular grafts via integrin activation by Atsushi Mahara, Manabu Shirai, Raghav Soni, Hue Thi Le, Kaito Shimizu, Yoshiaki Hirano, Tetsuji Yamaoka

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Targeting triple-negative breast cancer cells with a β1-integrin binding aptamer by Karlis Pleiko, Maarja Haugas, Vadims Parfejevs, Teodors Pantelejevs, Emilio Parisini, Tambet Teesalu, Una Riekstina

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Blockage of Osteopontin‐Integrin β3 Signaling in Infrapatellar Fat Pad Attenuates Osteoarthritis in Mice by Bingyang Dai, Yuwei Zhu, Xu Li, Zuru Liang, Shunxiang Xu, Shian Zhang, Zhe Zhang, Shanshan Bai, Wenxue Tong, Mingde Cao, Ye Li, Xiaobo Zhu, Wei Liu, Yuantao Zhang, Liang Chang, Patrick Shu‐hang Yung, Kevin Ki‐wai Ho, Jiankun Xu, To Ngai, Ling Qin

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Integrated bioinformatics analysis shows integrin alpha 3 is a prognostic biomarker for pancreatic cancer by Hu Fangfang, Zhao Liangtao, Wang Yang, Ye Hao, Tang Haodong, Zhou Jiahua

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Protective effects of macrophage-specific integrin α5 in myocardial infarction are associated with accentuated angiogenesis by Ruoshui Li, Bijun Chen, Akihiko Kubota, Anis Hanna, Claudio Humeres, Silvia C. Hernandez, Yang Liu, Richard Ma, Izabela Tuleta, Shuaibo Huang, Harikrishnan Venugopal, Fenglan Zhu, Kai Su, Jun Li, Jinghang Zhang, Deyou Zheng, Nikolaos G. Frangogiannis

“…Abstract Macrophages sense changes in the extracellular matrix environment through the integrins and play a central role in regulation of the reparative response after myocardial infarction. …”
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Inflammatory Th17 Cells Express Integrin αvβ3 for Pathogenic Function by Fang Du, Abhishek V. Garg, Karis Kosar, Saikat Majumder, David G. Kugler, Gerard Hernandez Mir, Maria Maggio, Matthew Henkel, Adam Lacy-Hulbert, Mandy J. McGeachy

“…We report that pro-inflammatory Th17 cells express high integrin β3 that is IL-23 dependent. Integrin β3 was not upregulated on all activated T cells; rather, integrin β3 was upregulated along with its functional partner integrin αv on effector Th17 cells and “ex-Th17” cells, and αvβ3hi RORγt+ cells expanded during EAE. …”
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Altered stress fibers and integrin expression in the Malpighian epithelium of Drosophila type IV collagen mutants by András A. Kiss, Nikoletta Popovics, Gábor Szabó, Katalin Csiszár, Mátyás Mink

“…Keywords: col4a1 mutation, Integrin misexpression, Stress fibers…”
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An Epithelial Integrin Regulates the Amplitude of Protective Lung Interferon Responses against Multiple Respiratory Pathogens. by Victoria A Meliopoulos, Lee-Ann Van de Velde, Nicholas C Van de Velde, Erik A Karlsson, Geoff Neale, Peter Vogel, Cliff Guy, Shalini Sharma, Susu Duan, Sherri L Surman, Bart G Jones, Michael D L Johnson, Catharine Bosio, Lisa Jolly, R Gisli Jenkins, Julia L Hurwitz, Jason W Rosch, Dean Sheppard, Paul G Thomas, Peter J Murray, Stacey Schultz-Cherry

“…The healthy lung maintains a steady state of immune readiness to rapidly respond to injury from invaders. Integrins are important for setting the parameters of this resting state, particularly the epithelial-restricted αVβ6 integrin, which is upregulated during injury. …”
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Exogenous laminin exhibits a unique vascular pattern in the brain via binding to dystroglycan and integrins by Jingsong Ruan, Karen K. McKee, Peter D. Yurchenco, Yao Yao

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