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Role of integrins in the development of fibrosis in the trabecular meshwork
Published 2023-10-01Subjects: “…integrins…”
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Integrin inside-out signaling and the immunological synapse.
Published 2012“…Integrins dynamically equilibrate between three conformational states on cell surfaces. …”
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Integrin activation--the importance of a positive feedback.
Published 2006“…Integrins mediate cell adhesion and are essential receptors for the development and functioning of multicellular organisms. …”
Journal article -
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Computational studies of talin-mediated integrin activation
Published 2013“… <p>Integrins are large heterodimeric (αβ) cell surface receptors that play a key role in the formation of focal adhesion complexes and are involved in various signal transduction pathways. …”
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Synthesis and Biological Evaluation of Cyclobutane-Based β3 Integrin Antagonists: A Novel Approach to Targeting Integrins for Cancer Therapy
Published 2023-08-01Subjects: “…integrin αvβ3…”
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Caveolae couple mechanical stress to integrin recycling and activation
Published 2022-10-01Subjects: “…integrin recycling…”
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Contribution of integrin adhesion to cytokinetic abscission and genomic integrity
Published 2022-12-01Subjects: “…integrin…”
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71
Roles of Membrane Domains in Integrin-Mediated Cell Adhesion
Published 2020-08-01Subjects: Get full text
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The Potential Role of Integrin Signaling in Memory and Cognitive Impairment
Published 2023-01-01Subjects: “…integrins…”
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Role of α and β Transmembrane Domains in Integrin Clustering
Published 2015-11-01Subjects: “…integrin…”
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Integrins and Exosomes, a Dangerous Liaison in Cancer Progression
Published 2017-07-01“…In this review we will discuss mounting evidence that contribute to the development of a new picture for integrins in cancer, highlighting the role of integrins in the processes that leads to tumor niche formation. …”
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The role of mechanical force and ROS in integrin-dependent signals.
Published 2013-01-01“…Cells are exposed to several types of integrin stimuli, which generate responses generally referred to as "integrin signals", but the specific responses to different integrin stimuli are poorly defined. …”
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Expression and function of beta1 integrins on human eosinophils
Published 1997-12-01Subjects: Get full text
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Control cell migration by engineering integrin ligand assembly
Published 2022-08-01“…Engineering peptide assembly that controls integrin ligand presentation on the molecular level possesses by far the highest ligand density, expanding the perspective of ligand-density-dependent modulation.…”
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Integrin Ligation Results in Nephrin Tyrosine Phosphorylation In Vitro.
Published 2016-01-01“…Here we present data showing that integrin engagement at the basal aspect of cultured podocytes results in nephrin tyrosine phosphorylation. …”
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Integrin α6 targeted cancer imaging and therapy
Published 2023-01-01Subjects: “…integrin α6…”
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Structural Insight into Integrin Recognition and Anticancer Activity of Echistatin
Published 2020-11-01“…The mutant with C-terminal HKGPAT truncation caused 6.4-, 7.0-, 11.7-, and 18.6-fold decreases in inhibiting integrins αvβ3, αIIbβ3, αvβ5, and α5β1. Mutagenesis of the C-terminus showed that the H44A mutant caused 2.5- and 4.4-fold increases in inhibiting αIIbβ3 and α5β1, and the K45A mutant caused a 2.6-fold decrease in inhibiting αIIbβ3. …”
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