Expression analysis of three immune genes Interferon-gamma, Mx and Interferon regulatory factor-1 of Japanese flounder ( Paralichthys olivaceus ) by Feng Zhang, Xuemei Qiu, Yang Liu, Juan Wang, Xipeng Li, Xiuli Wang

Subjects: “…Interferon-gamma…”
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Comparison of pegylated interferon monotherapy and de novo pegylated interferon plus tenofovir combination therapy in patients with chronic hepatitis B by Zheng C, Yan H, Zeng J, Cai S, Wu X

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An interferon-like small chemical compound CDM-3008 suppresses hepatitis B virus through induction of interferon-stimulated genes. by Yutaka Furutani, Mariko Toguchi, Yumi Shiozaki-Sato, Xian-Yang Qin, Etsuko Ebisui, Shoko Higuchi, Masayuki Sudoh, Harukazu Suzuki, Nobuaki Takahashi, Koichi Watashi, Takaji Wakita, Hideaki Kakeya, Soichi Kojima

“…Oral administration of nucleotide analogues and injection of interferon-α (IFNα) are used to achieve immediate suppression in replication of hepatitis B virus (HBV). …”
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Beta interferons in clinically isolated syndromes: a meta-analysis Interferons beta nas síndromes clínicas isoladas: meta-análise by Ailton Melo, Bernardo Rodrigues, Amit Bar-Or

Subjects: “…interferon…”
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Use of Piezoelectric Immunosensors for Detection of Interferon-Gamma Interaction with Specific Antibodies in the Presence of Released-Active Forms of Antibodies to Interferon-Gamma by Elena Don, Olga Farafonova, Suzanna Pokhil, Darya Barykina, Marina Nikiforova, Darya Shulga, Alena Borshcheva, Sergey Tarasov, Tatyana Ermolaeva, Oleg Epstein

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Retreatment of hepatitis C patients with pegylated interferon combined with ribavirin in non-responders to interferon plus ribavirin.... by Gonçales Neiva SL, Pavan Maria HP, Tozzo Raquel, Gonçales Eduardo SL, Angerami Adriana FCF, Vigani Aline G, Moma Camila A, Gonçales Fernando L

“…<p>Abstract</p> <p>Background</p> <p>More than 50% of hepatitis C viruses (HCV)-infected patients do not respond to the classical Interferon (IFN)/Ribavirin (RBV) combination therapy. …”
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Can interferon-gamma or interferon-gamma-induced-protein-10 differentiate tuberculosis infection and disease in children of high endemic areas? by Mohammed Ahmed Yassin, Roberta Petrucci, Kefyalew Taye Garie, Gregory Harper, Isabel Arbide, Melkamsew Aschalew, Yared Merid, Zelalem Kebede, Amin Ahmed Bawazir, Nabil Mohamed Abuamer, Luis Eduardo Cuevas

“…Diagnosis of childhood tuberculosis (TB) is difficult in high TB burden settings. Interferon-gamma-induced protein 10 (IP10) has been suggested as a marker of TB infection and disease, but its ability to differentiate the two conditions remains uncertain.To describe Interferon-gamma (INFγ) and IP10 expression in children with TB infection and disease and controls to assess their potential to differentiate latent and active TB.This was a cross sectional study of 322 1-15 years old children with symptoms of TB (28 confirmed, 136 probable and 131 unlikely TB), 335 children in contact with adults with pulmonary TB and 156 community controls in Southern Ethiopia. …”
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Interleukin 21 collaborates with interferon-γ for the optimal expression of interferon-stimulated genes and enhances protection against enteric microbial infection. by Shahram Solaymani-Mohammadi, Jay A Berzofsky

“…Here, we demonstrate that Il21r-/- mice are more susceptible to colonic microbial infection, and in the process discovered that the IL-21/IL-21R signaling axis surprisingly collaborates with the IFN-γ/IFN-γR signaling pathway to enhance the expression of interferon-stimulated genes (ISGs) required for protection, via amplifying activation of STAT1 in mucosal CD4+ T cells in a murine model of Citrobacter rodentium colitis. …”
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Interferon regulatory factor 8/interferon consensus sequence binding protein is a critical transcription factor for the physiological phenotype of microglia by Horiuchi Makoto, Wakayama Kouji, Itoh Aki, Kawai Kumi, Pleasure David, Ozato Keiko, Itoh Takayuki

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Prevention of adverse events of interferon γ gene therapy by gene delivery of interferon γ-heparin-binding domain fusion protein in mice by Mitsuru Ando, Yuki Takahashi, Takuma Yamashita, Mai Fujimoto, Makiya Nishikawa, Yoshihiko Watanabe, Yoshinobu Takakura

“…Sustained gene delivery of interferon (IFN) γ can be an effective treatment, but our previous study showed high levels of IFNγ-induced adverse events, including the loss of body weight. …”
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The chromatin remodeling protein ATRX positively regulates IRF3-dependent type I interferon production and interferon-induced gene expression. by Anne-Charlotte Stilp, Myriam Scherer, Patrick König, Axel Fürstberger, Hans A Kestler, Thomas Stamminger

“…Here, we show that depletion of ATRX results in an overall impaired antiviral state by decreasing transcription and subsequent secretion of type I IFNs, which is followed by reduced expression of interferon-stimulated genes (ISGs). ATRX interacts with the transcription factor interferon regulatory factor 3 (IRF3) and associates with the IFN-β promoter to facilitate transcription. …”
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Interferon and interferon-induced cytokines as markers of impending clinical progression in ANA+ individuals without a systemic autoimmune rheumatic disease diagnosis by Sonya T. Kim, Carolina Muñoz-Grajales, Shannon E. Dunn, Raphael Schneider, Sindhu R. Johnson, Zahi Touma, Zareen Ahmad, Dennisse Bonilla, Eshetu G. Atenafu, Linda T. Hiraki, Arthur Bookman, Joan Wither

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Type I interferon reaction to viral infection in interferon-competent, immortalized cell lines from the African fruit bat Eidolon helvum. by Susanne E Biesold, Daniel Ritz, Florian Gloza-Rausch, Robert Wollny, Jan Felix Drexler, Victor M Corman, Elisabeth K V Kalko, Samuel Oppong, Christian Drosten, Marcel A Müller

“…Here, we investigated interferon (IFN) response, -induction, -secretion and -signaling in epithelial-like cells of the relevant and abundant African fruit bat species, Eidolon helvum (E. helvum). …”
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Editorial: Type 1 interferon in pathologies, autoimmune diseases, and chronic viral infections: understanding the fascinating biologic role of type 1 interferons by Jean-Philippe Herbeuval

Subjects: “…IFN - interferon…”
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Analysis of Different Types of Interferon-Associated Retinopathy in Patients with Chronic Hepatitis C Virus Infection Treated with Pegylated Interferon Plus Ribavirin by Chia-Min Wu, Fu-Hsiung Su, Chih-Hsin Muo, Jou-Chen Huang, Meei-Maan Wu, Chih-Ching Yeh

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Type I interferons and interferon regulatory factors regulate TNF-related apoptosis-inducing ligand (TRAIL) in HIV-1-infected macrophages. by Yunlong Huang, Angelique Walstrom, Luwen Zhang, Yong Zhao, Min Cui, Ling Ye, Jialin C Zheng

“…We found that HIV-1 infection also induced interferon regulatory factor (IRF)-1, IRF-7 gene expression and signal transducers and activators of transcription 1 (STAT1) activation. …”
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USP18-based negative feedback control is induced by type I and type III interferons and specifically inactivates interferon α response. by Véronique François-Newton, Gabriel Magno de Freitas Almeida, Béatrice Payelle-Brogard, Danièle Monneron, Lydiane Pichard-Garcia, Jacob Piehler, Sandra Pellegrini, Gilles Uzé

“…Type I interferons (IFN) are cytokines that are rapidly secreted upon microbial infections and regulate all aspects of the immune response. …”
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The interferon lambda 4 rs368234815 predicts treatment response to pegylated-interferon alpha and ribavirin in hemophilic patients with chronic hepatitis C by Maryam Keshvari, Seyed Moayed Alavian, Bita Behnava, Ali Pouryasin, Heidar Sharafi

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Defective Interferon Gamma Production by Tumor-Specific CD8+ T Cells Is Associated With 5′Methylcytosine-Guanine Hypermethylation of Interferon Gamma Promoter by Megat Abd Hamid, Megat Abd Hamid, Xuan Yao, Xuan Yao, Craig Waugh, Samara Rosendo-Machado, Chris Li, Timothy Rostron, John Frankland, Yanchun Peng, Yanchun Peng, Tao Dong, Tao Dong

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Effects of Host and virus related factors on Interferon-α+ribavirin and Pegylated-interferon+ribavirin treatment outcomes in Chronic Hepatitis C patients by Saleem Sana, Liaqat Ali, Rehman Irshad-ur, Afzal Samia, Butt Sadia, Hussain Abrar, Zafar Shamail, Idrees Muhammad, Akram Madiha, Ali Muhammad, Butt Azeem

“…<p>Abstract</p> <p>Background</p> <p>Current standard therapy commonly followed for chronic Hepatitis C Virus (HCV) in Pakistan is interferon alpha plus ribavirin combination therapy (IFN α/ribavirin) and pegylated interferon plus ribavirin (PegIFN/ribavirin). …”
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