Published 2022-05-01
“…Cornelia Then,1,2 Chaterina Sujana,2– 4 Christian Herder,5– 7 Holger Then,8 Margit Heier,3,9 Christa Meisinger,10,11 Annette Peters,3,12 Wolfgang Koenig,12– 14 Wolfgang Rathmann,5,15 Haifa Maalmi,5,7 Katrin Ritzel,1 Michael Roden,5– 7 Michael Stumvoll,16 Barbara Thorand,2,3 Jochen Seissler1,2 1Department of
Internal Medicine IV, University Hospital of Ludwigs-Maximilians-University Munich, Munich, Germany; 2German Center for Diabetes Research (DZD), Partner Munich-Neuherberg, Munich, Germany; 3Institute of Epidemiology, Helmholtz Zentrum Munich – German Research Center for Environmental Health (GmbH), Neuherberg, Germany; 4Institute for Medical Information Processing, Biometry, and Epidemiology, Pettenkofer School of Public Health, Ludwigs-Maximilians-University Munich, Munich, Germany; 5German Center for Diabetes Research (DZD), Munich, Germany; 6Department of Endocrinology and Diabetology, Medical Faculty and University Hospital of the Heinrich-Heine-University Düsseldorf, Düsseldorf, Germany; 7Institute of Clinical Diabetology, German Diabetes Center, Leibniz Center for Diabetes Research at Heinrich-Heine-University Düsseldorf, Düsseldorf, Germany; 8Freie Waldorfschule Augsburg, Augsburg, Germany; 9KORA Study Centre, University Hospital Augsburg, Augsburg, Germany; 10Independent Research Group Clinical Epidemiology, Helmholtz Zentrum Munich – German Research Center for Environmental Health (GmbH), Neuherberg, Germany; 11Chair of Epidemiology, University Hospital Augsburg, Augsburg, Germany; 12DZHK (German Centre for Cardiovascular Research), Partner Site Munich Heart Alliance, Munich, Germany; 13Institute of Epidemiology and Medical Biometry, University of Ulm, Ulm, Germany; 14German Heart Center Munich, Technical University of Munich, Munich, Germany; 15Institute of Biometrics and Epidemiology, German Diabetes Center, Leibniz Institute at Heinrich-Heine-University Düsseldorf, Düsseldorf, Germany; 16Department of Medicine, University of Leipzig, Leipzig, GermanyCorrespondence: Cornelia Then, Medizinische Klinik und Poliklinik IV - Klinikum der Ludwig-Maximilians-Universität, Ziemssenstraße 1, München, 80336, Germany, Tel +4989440052111, Fax +4989440054956, Email cornelia.then@med.uni-muenchen.deIntroduction: Endothelin-1 and its prohormone C-terminal pro-endothelin-1 (CT-proET-1) have been linked to metabolic alterations, inflammatory responses and cardiovascular events in selected study populations. …”
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