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521
Cognitive Effects of Simulated Galactic Cosmic Radiation Are Mediated by ApoE Status, Sex, and Environment in APP Knock-In Mice
Published 2024“…Here, we investigated the central nervous system (CNS) effects of 0 Gy (sham) or 0.75 Gy five-ion GCRsim or 2 Gy gamma radiation (IRR) in 14-month-old female and male APP<sup>NL-F/NL-F</sup> knock-in (KI) mice bearing humanized ApoE3 or ApoE4 (APP;E3F and APP;E4F). …”
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Article -
522
Tunable ferroelectricity in Ruddlesden-Popper halide perovskites
Published 2020“…Extensive molecular dynamics simulations support the experimental results and identified the correlated reorientation of MA molecules and ion translations as the source of ferroelectricity. …”
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Journal Article -
523
Low-energy channel for mass transfer in Pt crystal initiated by molecule impact
Published 2021“…Crystal surface bombardment by atoms or molecules, neutral or ionized, occurs both in ambient conditions and in many technological operations, such as surface plasma treatment, ion implantation, etc. Recently, it was established that the impact of a molecule initiates the mass transfer in the one-dimensional Frenkel-Kontorova atomic chain more efficiently than that of a single atom. …”
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Journal Article -
524
Ionic covalent organic framework based electrolyte for fast-response ultra-low voltage electrochemical actuators
Published 2022“…Herein, we demonstrate that the actuation performance of an ionic two-dimensional covalent-organic framework based electrochemical actuator is improved through the ordered pore structure of opening up efficient ion transport routes. Specifically, the actuator shows a large peak to peak displacement (9.3 mm, ±0.5 V, 1 Hz), a fast-response time to reach equilibrium-bending (~1 s), a correspondingly high bending strain difference (0.38%), a broad response frequency (0.1-20 Hz) and excellent durability (>99%) after 23,000 cycles. …”
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Journal Article -
525
2023 roadmap for materials for quantum technologies
Published 2023“…These include both the inherent quantum bit systems and materials playing supportive or enabling roles, and cover trapped ions, neutral atom arrays, rare earth ion systems, donors in silicon, color centers and defects in wide-band gap materials, two-dimensional materials and superconducting materials for single-photon detectors. …”
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Journal Article -
526
Chemical composition and dynamics of biofilm matrix in hydrated, live Shewanella oneidensis biofilms
Published 2017“…Specifically, Shewanella oneidensis was used as a model organism and a novel technique combining System for Analysis at the Liquid Vacuum Interface (SALVI) with Time-of-Flight Secondary Ion Mass Spectrometry (TOF-SIMS) was applied to elucidate chemical composition and dynamics of S. oneidensis biofilm matrix. …”
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Thesis-Doctor of Philosophy -
527
Synthesis and reactivity of electron-deficient phosphorus(III) compounds
Published 2017“…In this view, we tuned the electronic properties of phosphenium ions by increasing their overall positive charge and by varying the extent of π-donation from the neighboring substituents to the central P atom. …”
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Thesis -
528
Modeling, optimization and thermal characterization of micropillar evaporator based high performance silicon vapor chamber
Published 2017“…We defined the micropillar patterns with deep-reactive-ion-etching (DRIE) and measured the temperature with embedded resistance-temperature-detectors (RTDs). …”
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Thesis -
529
Monocyte-derived extracellular vesicles, stimulated by Trypanosoma cruzi, enhance cellular invasion in vitro via activated TGF‐β1
Published 2024“…Host cell lEVs were released through Mtr interaction with host cell lipid raft domains, integrins, and mechanosensitive ion channels, whereupon [Ca2+]cyt increased (50 to 750 nM) within 15 s. lEV release and cell entry of T. cruzi, which increased up to 30 and 60 mpi, respectively, as well as raised actin depolymerization at 60 mpi, were all reduced by TRPC inhibitor, GsMTx‐4. …”
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Article -
530
Spin-ice physics and phase transitions in cadmium cyanide
Published 2019“…This thesis explores the structural ice analogue cadmium cyanide, Cd(CN)2, a cubic negative thermal expansion (NTE) material, in which the orientation of cyanide ions maps onto the spin orientation in spin-ices. …”
Thesis -
531
Electronic structure of paramagnetic transition metal complexes
Published 2017“…The distribution of metal ions across sites of different coordination geometry is a fundamental problem in inorganic chemistry (the text-book example is the spinel family) and we show here that the ligand-field stabilisation energy available to Ni<sup>II</sup> dominates the site distribution. …”
Thesis -
532
Synthesis of polymeric materials derived from abundant natural feedstocks using non-toxic heavy metals
Published 2024“…The conformational flexibility of the ligand was discussed in relation with varying steric demands, and the bonding environment was contrasted with related bismuth structures, which contain a +3 metal ion with a considerable size difference (<em>r</em><sub>Sc3+</sub> = 0.745, <em>r</em><sub>Bi3+</sub> = 1.03 Å).…”
Thesis -
533
Tunable anti-ambipolar vertical bilayer organic electrochemical transistor enable neuromorphic retinal pathway
Published 2024“…Increasing demand for bio-interfaced human-machine interfaces propels the development of organic neuromorphic electronics with small form factors leveraging both ionic and electronic processes. Ion-based organic electrochemical transistors (OECTs) showing anti-ambipolarity (OFF-ON-OFF states) reduce the complexity and size of bio-realistic Hodgkin-Huxley(HH) spiking circuits and logic circuits. …”
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Journal Article -
534
Topochemical cation exchange reactions of Ruddlesden-Popper oxides
Published 2024“…It was found that modulation of the Mn-site occupancy corresponds to a chequerboard ordering arrangement, which is coupled to the modulation of the equatorial oxygen ion site. MnSrNb2O7 undergoes a transition to an antiferromagnetically ordered state below TN = 39 K, in which the Mn2+ magnetic moments are orientated parallel to the z-axis in a G-type arrangement. …”
Thesis -
535
Sensorimotor control of Drosophila copulation
Published 2020“…By identifying those lines labelling our cells of interest, not only can we develop a genetic toolkit for manipulating their function, but we can also gain insights into their properties by identifying, for example, the expression of mechanosensitive ion channels such as nompC or the excitatory neurotransmitter ChAT. …”
Thesis -
536
Tumor cell-intrinsic signals promoting tolerance and adaptation to oncogenic kinase inhibition
Published 2024“…The work described in both parts was aided by two MS software solutions I developed: one to automate the generation of targeted acquisition methods for protein phosphosites and pathways of interest, and the other to retain quantitative information from fragment ion spectra with missing values. Together, this thesis reports new connections between cell signaling and kinase inhibitor response, and offers the intriguing hypothesis that SFK signaling may be a conserved barrier for maximally effective targeted cancer therapy.…”
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Thesis -
537
Sliding-mediated ferroelectric phase transition in CuInP2S6 under pressure
Published 2024“…Along the transformation pathway, the displacive-instable Cu ion serves as a pivot point that regulates the interlayer interaction in response to external pressure. …”
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Journal Article -
538
The novel quinoline derivative SKA-346 as a KCa3.1 channel selective activator
Published 2025“…We synthesized five quinoline derivatives and used electrophysiology to screen them on KCa3.1 and a panel of 14 other ion channels. One quinoline derivative, SKA-346, activated KCa3.1 with an EC50 of 1.9 μM and showed selectivity against the other channels. …”
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Journal Article -
539
Neuronal control of cardiac excitability in pro-hypertensive states
Published 2016“…Restoring the cGMP cyclic nucleotide dysfunction seen in these cells, rescues the ion channel phenotype and bring the Ca<sup>2+</sup> down to levels seen in the normotensive WKY neuron. …”
Thesis -
540
Mechanistic Studies of Interfacial Proton-Coupled Electron Transfer to Molecularly Defined Surface Sites
Published 2024“…With these observations we construct a mechanistic model in which I-PCET is not a single step, but a multi-step reaction sequence in which elementary I-PCET is gated by an ion exchange reaction between proton donor/acceptor species and proton-neutral supporting electrolyte at the electrode-electrolyte interface. …”
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Thesis