Optimization of Carbon Ion Treatment Plans by Integrating Tissue Specific α/β-Values for Patients with Non-Resectable Pancreatic Cancer. by Constantin Dreher, Christian Scholz, Mira Pommer, Stephan Brons, Hannah Prokesch, Swantje Ecker, Jürgen Debus, Oliver Jäkel, Stephanie E Combs, Daniel Habermehl

“…By the use of the treatment planning system Syngo RT Planning (Siemens, Erlangen, Germany) treatment plans with carbon ion beams have been created. Dose calculation was based on [Formula: see text]-values for both organs at risk (OAR) and the tumor. …”
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On the occurrence and characteristics of intense low-altitude electric fields observed by Freja by G. Marklund, L. Blomberg, C.-G. Fälthammar, P.-A. Lindqvist, L. Eliasson

“…In contrast to the observations within the auroral acceleration region characterized by intense converging electric fields associated with electron precipitation, upward ion beams and upward field-aligned currents, the intense electric fields observed by Freja are often found to be diverging and located within regions of downward field-aligned currents outside the electron aurora. …”
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Massively parallel direct writing of nanoapertures using multi-optical probes and super-resolution near-fields by Changsu Park, Soobin Hwang, Donghyun Kim, Nahyun Won, Runjia Han, Seonghyeon Jeon, Wooyoung Shim, Jiseok Lim, Chulmin Joo, Shinill Kang

“…However, conventional methods are limited by low throughput and scalability, and tend to use electron beams or focused-ion beams to create nanostructures. In this study, we developed a procedure for massively parallel direct writing of nanoapertures using a multi-optical probe system and super-resolution near-fields. …”
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On the occurrence and characteristics of intense low-altitude electric fields observed by Freja by G. Marklund, L. Blomberg, C.-G. Fälthammar, P.-A. Lindqvist, L. Eliasson

“…In contrast to the observations within the auroral acceleration region characterized by intense converging electric fields associated with electron precipitation, upward ion beams and upward field-aligned currents, the intense electric fields observed by Freja are often found to be diverging and located within regions of downward field-aligned currents outside the electron aurora. …”
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Conceptual model of IMSIC-250 cyclotron magnet by Kamran Farhoodi, Saeed Setayeshi, Amir Hossein Feghhi

“…Proton therapy with accelerator systems has been used in the last 30 years to destroy tumors by producing highly energetic ion beams. Although different systems have been introduced and designed to accelerate ions, the superconductive cyclotron accelerator is one of the most efficient treatment equipment compared to other systems. …”
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Geometrical Properties of the Nucleus and Chromosome Intermingling Are Possible Major Parameters of Chromosome Aberration Formation by Floriane Poignant, Ianik Plante, Zarana S. Patel, Janice L. Huff, Tony C. Slaba

“…Using the Monte Carlo codes Relativistic Ion Tracks (RITRACKS) and Radiation-Induced Tracks, Chromosome Aberrations, Repair and Damage (RITCARD), we investigated how geometrical properties of the cell nucleus, irradiated with ion beams of linear energy transfer (LET) ranging from 0.22 keV/μm to 195 keV/μm, influence the yield of simple and complex exchanges. …”
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Laser Ion Acceleration: Status and Perspectives for Fusion by Ma W., Kiefer D., Henig A., Bin J., Allinger K., Gross M., Habs D., Thirolf P.G., Schreiber J.

“…Based on the Radiation Pressure Acceleration mechanism, laser-accelerated ion beams can be generated with solid-state density, thus exceeding beams from conventional accelerators by about 14 orders of magnitudes. …”
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The Influence of a Magnetic Field on the Sorption of Radionuclides by Clinoptilolite and Composite Sorbents Based on Zeolites by Oleksii Yu. Lonin, Volodymyr V. Levenets, Oleksandr M. Bovda

“…The complex made it possible to carry out all the main methods of analysis using ion beams. The targets were placed in the exit, at the Chamber for PIXE. …”
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Prospects for the Application of Surface Treatment of Alloys by Electron Beams in State-of-the-Art Technologies by Yu. F. Ivanov, V. Е. Gromov, D. V. Zaguliaev, S. V. Konovalov, Yu. A. Rubannikova, A. P. Semin

“…The advantages of pulsed electron beam application as compared with laser beams, plasma flows, ion beams are mentioned. Promising trends of the electron-beam processing application are analysed: (1) the surface smoothing, the elimination of surface microcracks with simultaneous change in structural-phase state of the surface layer for creating the high production technologies of finishing treatment of critical metal products of intricate shape from Ti–6Al–4V alloy and titanium, steels of different classes, WC–10 wt.% Co hard alloy, aluminium; (2) the removal of microburrs being formed in manufacturing of precision moulds (SKD11 steel) and biomedical materials (Ti–6Al–4V alloy); (3) the finishing surface treatment of moulds and dies; (4) the improvement of functional properties of metallic biomaterials: stainless steel, titanium and its alloys, the titanium-nickelide-based alloys possessing the shape memory effect, magnesium alloys; (5) the treatment of medical materials and implants; (6) the formation of surface alloys for powerful electrodynamic systems; (7) the improvement of characteristics of aircraft engine and compressor blades; (8) the formation of thermobarrier coatings being applied to combustion-chamber surface; (9) the increase in fatigue service life of steels and alloys; (10) the hardening of rails’ tread surface. …”
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A small step towards solving the global chip shortage problem – physical failure analysis by Tan, Yi Kai

“…Hence, this study was performed to provide solutions for the uniform deprocessing of copper interconnects using Xe+ Plasma Focused Ion Beams (Xe+ PFIBs), through the improvement of existing Gas-Assisted Milling (GAM) techniques and the pioneering of surface disruption strategies to counter channelling effects in aligned grains. …”
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Time-resolved characteristics of deuteron-beam generated by plasma focus discharge by Lim, Lian Kuang, Yap, Seong Ling, Bradley, D.A.

“…The plasma focus has been widely investigated as a radiation source, including as ion-beams, electron-beams and as a source of x-ray and neutron production, providing considerable scope for use in a variety of technological situations. …”

Microdosimetry and Dose-Averaged LET Calculations of Protons in Liquid Water: A Novel Geant4-DNA Application by Anna Baratto-Roldán, Anna Baratto-Roldán, Alejandro Bertolet, Alejandro Bertolet, Giorgio Baiocco, Alejandro Carabe, Miguel Antonio Cortés-Giraldo

“…Microdosimetry provides a theoretical framework for the description of these events, and has been used in several studies to address problems such as the characterization of Linear Energy Transfer (LET) and Relative Biological Effectiveness (RBE) of ion beams for proton therapy applications. Microdosimetry quantities and their distributions can be obtained by means of Monte Carlo simulations. …”
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Heavy-Ion-Induced Lung Tumors: Dose- & LET-Dependence by Polly Y. Chang, James Bakke, Chris J. Rosen, Kathleen A. Bjornstad, Jian-Hua Mao, Eleanor A. Blakely

“…The goal of this study is to reduce uncertainties in estimating particle-radiation-induced risk of lung tumorigenesis for manned travel into deep space by improving our understanding of the high-LET-dependent dose-response from exposure to individual ion beams after low particle doses (0.03–0.80 Gy). …”
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First direct comparison of whole beam and single beamlet divergences in a negative ion source with simultaneous BES and CFC tile calorimetry measurements by A. Hurlbatt, F. Bonomo, A. Pimazzoni, P. Veltri, M. Agostini, M. Barbisan, M. Brombin, R. Delogu, U. Fantz, B. Heinemann, N. den Harder, G. Orozco, C. Poggi, L. Schiesko, G. Serianni, M. Ugoletti, C. Wimmer

“…The measurement of single beamlet divergence is challenging due to the multi-beamlet nature of the negative ion sources that are required for such systems; diagnostic systems compatible with large high power ion beams can only provide spatially averaged measurements, leading to mixing of beamlet signals within diagnostic results. …”
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TOF Analysis of Ions Accelerated at High Repetition Rate from Laser-Induced Plasma by Evan Russell, Valeria Istokskaia, Lorenzo Giuffrida, Yoann Levy, Jaroslav Huynh, Martin Cimrman, Martin Srmž, Daniele Margarone

“…Generation methods such as target normal sheath acceleration or similar allow for collimated laminar ion beams to be produced in a compact environment through the use of short-burst terawatt lasers and are a growing field of investment. …”
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Feasibility and Safety of Repeated Carbon Ion Radiotherapy for Locally Advanced Unresectable Pancreatic Cancer by Masahiko Okamoto, Shintaro Shiba, Shohei Okazaki, Yuhei Miyasaka, Kei Shibuya, Hiroki Kiyohara, Tatsuya Ohno

“…Purpose: The feasibility and safety of re-irradiation with carbon ion beams for locally recurrent unresectable pancreatic cancer (URPC) after carbon ion radiotherapy (CIRT) was evaluated. …”
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Complementary sample preparation strategies (PVD/BEXP) combining with multifunctional SPM for the characterizations of battery interfacial properties by Handian Pan, Yue Chen, Wenhui Pang, Hao Sun, Jiaxin Li, Yingbin Lin, Oleg Kolosov, Zhigao Huang

“…In this method, commercial battery materials can be either directly grown on the current collector substrates, or polished by obliqued Ar-ion beams to get a nanoscale flat surface which allows the multifunctional SPM to study sample directly in the liquid electrolyte or in protective oxygen/H2O free environment. …”
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Impact of Hypoxia on Carbon Ion Therapy in Glioblastoma Cells: Modulation by LET and Hypoxia-Dependent Genes by Samuel Valable, Aurélie N. Gérault, Gaëlle Lambert, Marine M. Leblond, Clément Anfray, Jérôme Toutain, Karim Bordji, Edwige Petit, Myriam Bernaudin, Elodie A. Pérès

“…Hypoxia-induced radioresistance was studied in two human GB cells (U251, GL15) exposed to X-rays or to carbon ion beams with various LET (28, 50, 100 keV/µm), and in genetically-modified GB cells with downregulated EPO signaling. …”
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Laser-driven neutrons for time-of-flight experiments? by Millán-Callado M.A., Guerrero C., Quesada J.M., Gómez J., Fernández B., Lerendegui-Marco J., Rodríguez-González T., Domingo-Pardo C., Tarifeño-Saldivia A., Benlliure J., Cortina D., Martín L., Peñas J., Cano-Ott D., Martínez T.

“…In the last decades, the development of ultra-short (femtosecond) and ultra-high power (> 1018 W/cm2) lasers has opened the door to a vast number of new applications, including the production and acceleration of pulsed ion beams. These have been recently used to produce pulsed neutron beams, reaching fluxes per pulse similar and even higher than those of conventional neutron beams, hence becoming an alternative for the pulsed neutron beam users community. …”
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Application of dense plasma focus devices and lasers in the radiation material sciences for the goals of inertial fusion beyond ignition by V. A. Gribkov, I. V. Borovitskaya, E. V. Demina, E. E. Kazilin, S. V. Latyshev, S. A. Maslyaev, V. N. Pimenov, T. Laas, M. Paduch, S. V. Rogozhkin

“…By means of 1-ns laser interferometry and neutron measurements, the characteristics of plasma streams and fast ion beams, as well as the dynamics of their interaction with solid-state targets, have been investigated. 3D profilometry, optical and scanning electron microscopy, atomic emission spectroscopy, X-ray elemental and structural analyses, and precise weighing of specimens before and after irradiation have provided data on the roughening threshold and the susceptibility to damage of the materials under investigation. …”
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