The Application of Ultra-High-Performance Liquid Chromatography Coupled with a LTQ-Orbitrap Mass Technique to Reveal the Dynamic Accumulation of Secondary Metabolites in Licorice u... by Da Li, Guojie Xu, Guangxi Ren, Yufeng Sun, Ying Huang, Chunsheng Liu

“…In this study, the secondary metabolites from licorice under two different methods of stress were investigated by ultra-high-performance liquid chromatography coupled with hybrid linear ion trap–Orbitrap mass spectrometry (UHPLC-LTQ-Orbitrap-MS). …”
Get full text

Laboratory Benchmark of n ≥ 4 Dielectronic Recombination Satellites of Fe xvii by Gabriel J. Grell, Maurice A. Leutenegger, Pedro Amaro, José R. Crespo López-Urrutia, Chintan Shah

“…We calculated cross sections for the dielectronic recombination (DR) satellite lines of Fe xvii and benchmarked our predictions with experimental cross sections of Fe xvii resonances that were monoenergetically excited in an electron-beam ion trap. We extend the benchmark to all resolved DR and direct electron-impact excitation (DE) channels in the experimental data set, specifically the n ≥ 4 DR resonances of Fe xvii , complementing earlier investigations of n = 3 channels. …”
Get full text

LC-MS/MS Screening of Phenolic Compounds in Wild and Cultivated Grapes <i>Vitis amurensis</i> Rupr. by Mayya Razgonova, Alexander Zakharenko, Konstantin Pikula, Yury Manakov, Sezai Ercisli, Irina Derbush, Evgeniy Kislin, Ivan Seryodkin, Andrey Sabitov, Tatiana Kalenik, Kirill Golokhvast

“…The metabolome analysis was performed by liquid chromatography in combination with ion trap mass spectrometry. The results showed the presence of 118 compounds in ethanolic extracts of <i>V. amurensis</i> grapes. …”
Get full text

Accumulation of oxysterols in the erythrocytes of COVID-19 patients as a biomarker for case severity by Alaa Khedr, Maan T. Khayat, Ahdab N. Khayyat, Hany Z. Asfour, Rahmah A. Alsilmi, Ahmed K. Kammoun

“…The erythrocyte homogenate extract was analyzed using linear ion trap mass spectrometry combined with high-performance liquid chromatography. …”
Get full text

Study on the Mass Spectrometry Cleavage Pattern of Quinolone Antibiotics by Susu Fan, Hui Lu, Chunjian Li, Meng Cai, Jian Shi

“…Methods: To collect data, we employed triple quadrupole linear ion trap mass spectrometry in electrospray positive ion mode. …”
Get full text

Cryogenic ion mobility-mass spectrometry for the study of conformations of host-guest complexes by Keijiro Ohshimo, Xi He, Ryosuke Ito, Kengo Tsunoda, Sota Tainaka, Fuminori Misaizu

“…The VT-Cryo-IM-MS consists of an electrospray ionization source, a quadrupole ion trap, a cryogenic ion drift tube, and a time-of-flight mass spectrometer. …”
Get full text

Analysis of linoleoyl and oleoyl macrogolglycerides by high performance liquid chromatography coupled to the atmospheric pressure photoionization mass spectrometry by Kemel Kamilia, Libong Danielle, Solgadi Audrey, Tfaili Sana, Baillet-Guffroy Arlette, Laugel Cécile

“…The ionization source used was atmospheric pressure photoionization (APPI) and the analyzer was LTQ-Orbitrap® (hybrid analyzer: double linear ion trap coupled to a Fourier transform orbital trap). …”
Get full text

Measurements of the Reaction Rate Coefficients of Atomic Hydrogen with Astrochemical Anions: CN− and C3N− by Christine Lochmann, Sruthi Purushu Melath, Robert Wild, Ersin Yurtsever, Alberto Martín Santa Daría, Lola González-Sánchez, Francesco A. Gianturco, Roland Wester

“…We present the temperature-dependent reaction rate coefficients of CN ^− and C _3 N ^− with atomic hydrogen in the temperature range from 7 to 290 K, measured in a 16-pole radio-frequency ion trap. The rate of C _3 N ^− with H steadily increases toward lower temperatures, while the rate coefficients for the CN ^− + H system show a sudden change around 160 K. …”
Get full text

Development and Validation of a Highly Sensitive and Rapid LC-MS³ Strategy to Determine Oxcarbazepine and Its Active Metabolite in the Serum of Patients with Epilepsy an... by Zhengchao Ji, Tingting Li, Xin Zhao, Wei Ma, Yanyan Li, Jing Huang

“…A sensitive and rapid bioanalytical method based on the LC-triple-stage fragmentation (LC-MS³) strategy on a hybrid triple quadrupole-linear ion trap mass spectrometer in combination with protein precipitation extraction for sample pretreatment has been developed and validated for the simultaneous determination of the antiepileptic drug oxcarbazepine (OXC) and its main active metabolite (MHD) in human serum. …”
Get full text

Quality Evaluation of Tetrastigmae Radix from Two Different Habitats Based on Simultaneous Determination of Multiple Bioactive Constituents Combined with Multivariate Statistical A... by Haijie Chen, Yongyi Zhou, Jia Xue, Jiahuan Yuan, Zhichen Cai, Nan Wu, Lisi Zou, Shengxin Yin, Wei Yang, Xunhong Liu, Jianming Cheng, Li Tang

“…To distinguish and evaluate the quality of ES and WS, an analytical method based on ultrafast performance liquid chromatography coupled with triple quadrupole-linear ion trap mass spectrometry (UFLC-QTRAP-MS/MS) was established for the simultaneous determination of 60 constituents including 25 flavonoids, 9 phenolic acids, 15 amino acids, and 11 nucleosides in 47 samples from ES and WS. …”
Get full text

Comprehensive Secondary Metabolite Profiling Toward Delineating the Solid and Submerged-State Fermentation of Aspergillus oryzae KCCM 12698 by Su Y. Son, Sunmin Lee, Digar Singh, Na-Rae Lee, Dong-Yup Lee, Dong-Yup Lee, Dong-Yup Lee, Choong H. Lee

“…Thus, we performed time resolved (0, 4, 8, 12, 16 day) secondary metabolite profiling for A. oryzae KCCM 12698 cultivated on malt extract agar and broth (MEA and MEB) under solid-state fermentation (SSF) and submerged fermentation (SmF) conditions using the ultrahigh performance liquid chromatography-linear trap quadrupole-ion trap-mass spectrometry (UHPLC-LTQ-IT-MS/MS) followed by multivariate analyses. …”
Get full text

Determination of amlodipine in human plasma by electrospray ionization LC-MS/MS method: validation and its stability studies by Anusak Sirikatitham, Kamon Panrat, Niwan Tanmanee

“…Detection was performed on a API 2000 QTRAP quadrupole linear ion trap mass spectrometer via turboion spray ionization. …”
Get full text

Methyl carbamates of phosphatidylethanolamines and phosphatidylserines reveal bacterial contamination in mitochondrial lipid extracts of mouse embryonic fibroblasts by Andrea Castellaneta, Vito Porcelli, Ilario Losito, Serena Barile, Alessandra Maresca, Valentina Del Dotto, Ludovica Sofia Guadalupi, Cosima Damiana Calvano, Valerio Carelli, Luigi Palmieri, Tommaso R. I. Cataldi

“…Abstract The occurrence of methyl carbamates of phosphatidylethanolamines and phosphatidylserines in the lipid extract of mitochondria obtained from mouse embryonic fibroblasts was ascertained by hydrophilic interaction liquid chromatography with electrospray ionization single and multi-stage mass spectrometry, performed using sinergically a high resolution (quadrupole-Orbitrap) and a low resolution (linear ion trap) spectrometer. Two possible routes to the synthesis of methyl carbamates of phospholipids were postulated and evaluated: (i) a chemical transformation involving phosgene, occurring as a photooxidation by-product in the chloroform used for lipid extraction, and methanol, also used for the latter; (ii) an enzymatic methoxycarbonylation reaction due to an accidental bacterial contamination, that was unveiled subsequently on the murine mitochondrial sample. …”
Get full text

Comprehensive Identification of Glycosphingolipids in Human Plasma Using Hydrophilic Interaction Liquid Chromatography—Electrospray Ionization Mass Spectrometry by Karel Hořejší, Robert Jirásko, Michaela Chocholoušková, Denise Wolrab, David Kahoun, Michal Holčapek

“…The hydrophilic interaction liquid chromatography coupled to electrospray ionization linear ion trap tandem mass spectrometry (HILIC-ESI-LIT-MS/MS) is used for GSL analysis in the human plasma extract. …”
Get full text

Rapid Characterization of Triterpene Saponins from <i>Zornia brasiliensis</i> by HPLC-ESI-MS/MS by Yuri Mangueira Nascimento, Lucas Silva Abreu, Ramon Leal Lima, Vicente Carlos O. Costa, José Iranildo Miranda de Melo, Raimundo Braz-Filho, Marcelo Sobral Silva, Josean Fechine Tavares

“…A specific methodology to obtain a saponin-enriched fraction and high-performance liquid chromatography coupled with diode array detection, ion trap mass spectrometry, and TOF-MS (HPLC-DAD-ESI-MS/MS) was applied for the analysis of triterpene saponins. …”
Get full text

Occurrence of Selected Known or Suspected Endocrine-Disrupting Pesticides in Portuguese Surface Waters Using SPME-GC-IT/MS by José Vera, Virgínia Cruz Fernandes, Luísa Correia-Sá, Catarina Mansilha, Cristina Delerue-Matos, Valentina F. Domingues

“…A multiresidue analytical methodology based on a solid-phase microextraction (SPME), followed by gas chromatography-ion trap mass spectrometry (GC–IT/MS), has been developed for trace analysis of 20 known or suspected endocrine-disrupting pesticides. …”
Get full text

The UPLC–ESI–QqQLIT–MS/MS method for quantitative determination of phytochemicals in ethanolic extracts of different parts of eight Ficus species: Development and validation by Sunil Kumar, Awantika Singh, Arun K. Kushwaha, Rinkey Tiwari, Lal B. Chaudhary, Mukesh Srivastava, Brijesh Kumar

“…Ficus and validation of the ultra performance liquid chromatography–electrospray ionization hybrid triple quadrupole–linear ion trap–tandem mass spectrometry (UPLC–ESI–QqQLIT–MS/MS) method in a multiple-reaction monitoring (MRM) mode for the quantitative determination of 19 phytochemicals. …”
Get full text

Control system for an underwater coded aperture miniature mass spectrometer by Rafael Bento Serpa, Justin A. Keogh, Thomas Jablonski, Charles B. Parker, Stefan M. Goetz, M.Bonner Denton, Harold F. Hemond, Jeffrey T. Glass, Nicolas Cassar, Jason J. Amsden

“…Over the past two decades, underwater membrane inlet mass spectrometry has emerged as a leading technology for in situ dissolved gas analysis, leveraging various mass analyzers such as quadrupole, ion trap, and cycloidal systems. While quadrupoles and ion traps face challenges such as water vapor interference and resolution limitations, cycloidal analyzers offer higher resolution at low mass-to-charge ratios with reduced power requirements. …”
Get full text

Analysis of Metabolite Accumulation Related to Pod Color Variation of <i>Caragana intermedia</i> by Feiyun Yang, Tianrui Yang, Kun Liu, Qi Yang, Yongqing Wan, Ruigang Wang, Guojing Li

“…A total 557 metabolites, which could be classified into 21 groups, were detected in the pod extracts using liquid chromatography coupled with ESI-triple quadrupole-linear ion trap mass spectrometer (LC-ESI-MS/MS). Metabolomics analysis revealed significant differences in 15 groups of metabolites between red and green pods, including amino acids, nucleotide derivatives, flavonoids, and phytohormones. …”
Get full text

Energy-Resolved Mass Spectrometry and Mid-Infrared Spectroscopy for Purity Assessment of a Synthetic Peptide Cyclised by Intramolecular Huisgen Click Chemistry by Alicia Maroto, Ricard Boqué, Dany Jeanne Dit Fouque, Antony Memboeuf

“…On the one hand, mixtures of both peptides were subjected to collision-induced dissociation tandem mass spectrometry (CID MS/MS) experiments in an ion trap mass spectrometer at several excitation energies. …”
Get full text