anemia as public health problem among child under five years age by shatha ahmed

“…Regarding causes of anemia iron deficiency was the major causes in 67.9% of child under five years age…”
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Diagnostic Value of Upper and Lower Endoscopy in Assessment of Patients with Microcytic Hypochromic Anaemia without Site-specific Gastrointestinal Manifestations by Mohammed Tag-Adeen Said Hussien, Huda Abdelhamied Mohammed Dardeer, Mahmoud Aboelsoad Gehlan Ali *, Asmaa Abd elhakim Nafady

“…Background: Iron deficiency anemia (IDA), is often caused by digestive disorder and should always be assessed, as its causes could be severe illness such as cancer. …”
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Prenatal suspicion and postnatal diagnosis of a patient with cystic fibrosis by Melissa Toledo Licourt, Ana Laura Téllez García, Deysi Licourt Otero

“…After 2 months, she re-entered due to respiratory manifestations, in the nutritional evaluation her height and weight was below the third percentile, she had skin-pale pallor, demonstrating anemia due to iron deficiency and light hair color. Given the prenatal history and the predominance of digestive and respiratory manifestations, it is decided to perform sweat electrolyte examination in 2 moments, which are negative. …”
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Ribosome Recycling by ABCE1 Links Lysosomal Function and Iron Homeostasis to 3ʹ UTR-Directed Regulation and Nonsense-Mediated Decay by Xiaoqiang Zhu, He Zhang, Joshua T. Mendell

“…Because of the sensitivity of the Fe-S cluster of ABCE1 to iron availability and reactive oxygen species, these findings reveal an unanticipated vulnerability of 3ʹ UTR-directed regulation to lysosomal dysfunction, iron deficiency, and oxidative stress.…”
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Large-scale genetic investigation reveals genetic liability to multiple complex traits influencing a higher risk of ADHD by Luis M. García-Marín, Adrián I. Campos, Gabriel Cuéllar-Partida, Sarah E. Medland, Scott H. Kollins, Miguel E. Rentería

“…Our results reveal that genetic variants associated with iron deficiency anemia (ICD10), obesity, type 2 diabetes, synovitis and tenosynovitis (ICD10), polyarthritis (ICD10), neck or shoulder pain, and substance use in adults display partial genetic causality on ADHD risk in children. …”
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Prenatal suspicion and postnatal diagnosis of a patient with cystic fibrosis by Melissa Toledo Licourt, Ana Laura Téllez García, Deysi Licourt Otero

“…After 2 months, she re-entered due to respiratory manifestations, in the nutritional evaluation her height and weight was below the third percentile, she had skin-pale pallor, demonstrating anemia due to iron deficiency and light hair color. Given the prenatal history and the predominance of digestive and respiratory manifestations, it is decided to perform sweat electrolyte examination in 2 moments, which are negative. …”
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Myelin oligodendrocyte glycoprotein antibody-associated disease as a novel presentation of central nervous system autoimmunity in a pediatric patient with Wiskott-Aldrich syndrome by Vivien X. Xie, Wilson File, Christina Wiedl, Brant R. Ward, Blachy Dávila Saldaña, Michael D. Keller, Alexandra B. Kornbluh

“…Case Presentation We describe the case of a five-year-old boy with refractory thrombocytopenia and iron deficiency anemia who developed relapsing bilateral optic neuritis. …”
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Aft2, a novel transcription regulator, is required for iron metabolism, oxidative stress, surface adhesion and hyphal development in Candida albicans. by Ning Xu, Xinxin Cheng, Qilin Yu, Kefan Qian, Xiaohui Ding, Ruming Liu, Biao Zhang, Laijun Xing, Mingchun Li

“…Deletion of AFT2 reduced cellular iron accumulation under iron-deficient conditions. Furthermore, both reactive oxygen species (ROS) generation and superoxide dismutase (SOD) activity were remarkably increased in the aft2Δ/Δ mutant, which were thought to be responsible for the defective responses to oxidative stress. …”
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The Interplay between Intracellular Iron Homeostasis and Neuroinflammation in Neurodegenerative Diseases by Jaewang Lee, Dong-Hoon Hyun

“…In order to protect against harmful effects, the intracellular system regulates cellular iron levels through iron regulatory mechanisms, including hepcidin–ferroportin, divalent metal transporter 1 (DMT1)–transferrin, and ferritin–nuclear receptor coactivator 4 (NCOA4). During iron deficiency, DMT1–transferrin and ferritin–NCOA4 systems increase intracellular iron levels via endosomes and ferritinophagy, respectively. …”
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Cardiovascular, liver, and renal toxicity associated with an intravenous ferric carboxymaltose similar versus the originator compound by Toblli JE, Cao G, Rico L, Angerosa M

“…Jorge E Toblli, Gabriel Cao, Luis Rico, Margarita Angerosa Laboratory of Experimental Medicine, Hospital Alemán, School of Medicine, University of Buenos Aires, Buenos Aires, Argentina Background: Ferric carboxymaltose (FCM) is a stable, non-dextran-based intravenous iron complex used to treat iron deficiency of various etiologies. As FCM is a nonbiological complex drug and cannot be fully characterized by physicochemical analyses, it is important to demonstrate in nonclinical models that FCM similars (FCMS) have similar biodistribution. …”
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Effect of Bariatric Surgery on Metabolic Diseases and Underlying Mechanisms by Yu Ji, Hangil Lee, Shawn Kaura, James Yip, Hao Sun, Longfei Guan, Wei Han, Yuchuan Ding

“…Lastly, some of the complications of bariatric surgery, including osteoporosis, iron deficiency/anemia, and diarrhea, as well as their potential mechanisms, are described.…”
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Impact of Malaria Severity on Serum Levels of Hepcidin and Iron Status in Children by Oluboyo, O. Adeola, Iwuchukwu Theodora, Oluboyo, O. Bernard, Olayanju, O. Ayodeji

“…The study concluded that severe malaria may cause the upregulation of hepcidin and the increased hepcidin could put the subject at risk of iron deficiency anemia. The study suggests that hepcidin could help in the evaluation of severe and non-severe malaria and also be used to monitor the progression of malaria infection.…”
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Iron salt supplementation during gestation and gestational diabetes mellitus by Vanessa Iribarrem Avena Miranda, Tatiane da Silva Dal Pizzol, Marysabel Pinto Telis Silveira, Sotero Serrate Mengue, Mariângela Freitas da Silveira, Bárbara Heather Lutz, Andréa Dâmaso Bertoldi

“…This evidence supports the existing national and international guidelines, in which prophylactic iron supplementation is recommended for all pregnant women as soon as they initiate antenatal care in order to prevent iron deficiency anemia.…”
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Effect of consuming zinc-fortified bread on serum zinc and iron status of zinc-deficient women: A double blind, randomized clinical trial by Akbar Badii, Niloufar Nekouei, Mohammad Fazilati, Mohammad Shahedi, Sajad Badiei

“…After iron deficiency, zinc deficiency is the major micronutrient deficiency in developing countries, and staple food fortification is an effective strategy to prevent and improve it among at-risk-populations. …”
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Frequency of Hematologic and Nonhematologic Conditions in Pediatric Patients with Vascular Anomalies: A Pediatric Health Information System Database Study by Bryony Lucas, Sindhoosha Malay, Irina Pateva

“…The most common hematologic conditions were thrombocytopenia, iron deficiency anemia, and venous thrombosis. The most common nonhematologic condition was electrolyte imbalances. …”
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Nutritional Deficiencies, the Absence of Information and Caregiver Shortcomings: A Qualitative Analysis of Infant Feeding Practices in Rural China. by Ai Yue, Lauren Marsh, Huan Zhou, Alexis Medina, Renfu Luo, Yaojiang Shi, Linxiu Zhang, Kaleigh Kenny, Scott Rozelle

“…Age-appropriate complementary feeding can stimulate children's physical and cognitive development, but in its absence it leads to iron-deficiency anemia. We suggest that steps be taken to educate caregivers to improve complementary feeding of their infants and children.…”
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DEVELOPMENT OF A NEW IMMUNOMODULATING DRUG TIMOFER by B. M. Kholnazarov, G. M. Bobiev, N. D. Bunyatyan

“…The developed immunomodulatory drug timofer showed a high therapeutic efficacy in the treatment of iron deficiency anemia patients with inflammatory processes and traumatic injuries of the maxillofacial region, with chronic inflammatory diseases of the the genitals (CMV, HSV, chlamydia, chronic endometritis, chronic salpingoopharitis, ureaplasmosis) with chronic bronchitis, chronic obstructive bronchitis, bronchial asthma, pneumonia, chronic glomerulonephritis, and chronic renal failure complicated by anemia Bright, withrheumatic diseases, gynecological patients with anemia of moderate and severe degrees of severity, at surgical treatment of patients with suppurative lung disease, heart disease and chronic pericarditis operated with cardiopulmonary bypass. …”
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Prevalence of anemia and deficiencies of iron, folic acid and vitamin B12 in an Indigenous community from the Venezuelan Amazon with a high incidence of malaria by Maria Nieves García-Casal, Irene Leets, Carmen Bracho, Mariana Hidalgo, Gilberto Bastidas, Ana Gomez, Ana Peña, Hilda Pérez

“…The number of cases of anemia due to iron deficiency could be underestimated, since ferritin concentration increased as a acute phase protein, although prevalence data was also analyzed with a cutoff point of 30 μg/L for ferritin concentration.…”
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Iron supplementation regulates the progression of high fat diet induced obesity and hepatic steatosis via mitochondrial signaling pathways by Naho Kitamura, Yoko Yokoyama, Hiroki Taoka, Utana Nagano, Shotaro Hosoda, Tanon Taworntawat, Anna Nakamura, Yoko Ogawa, Kazuo Tsubota, Mitsuhiro Watanabe

“…Abstract Disruption of iron metabolism is closely related to metabolic diseases. Iron deficiency is frequently associated with obesity and hepatic steatosis. …”
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Suplementação de vitaminas e minerais em recém-nascidos prematuros: Uma revisão integrativa da literatura by Daniella Ramiro Vittorazzi, Clarissa Paneto Sulz, Larissa Pandolfi Soares

“…However, ESPGHAN and SBP recommend its routine use for preterm in general. Iron deficiency is the most common nutritional deficiency in childhood and is associated with impaired neurodevelopment, so its supplementation is highly recommended. …”
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