The Use of Targeted Next Generation Sequencing to Explore Candidate Regulators of TGF-β1’s Impact on Kidney Cells by Bo Wang, Guanyu Ji, Haroon Naeem, Haroon Naeem, Junwen Wang, Phillip Kantharidis, David Powell, David Powell, Sharon D. Ricardo

“…Aims/Hypothesis: Transforming growth factor-beta (TGF-β1) plays an important regulatory role in the progression of chronic kidney failure. Further, damage to kidney glomerular mesangial cells is central to the progression of diabetic nephropathy. …”
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Acute Kidney Injury In Children Admitted In Pediatric Intensive Care Unit by Aly ELkazaz, Hafez M. Bazaraa, Doaa Salah, Ahmed El Nahas, Shaimaa Sayed

“…Background: Acute kidney injury (AKI) poses a significant burden for the society, in terms of health resource use during the acute phase, and the potential long-term sequelae including development of chronic kidney disease and kidney failure. Aim of the work: to investigate the risk of development of AKI in critically ill children. …”
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Diuretic activity of some 4- and 3-thio-substituted 1,2,4-triazoles with fluorophenyl fragments by O. A. Bihdan, V. V. Parchenko, B. P. Kyrychko, T. V. Zvenyhorodska, D. M. Romanina

“…Diuretics increase the volume of urine and sodium excretion, and therefore are often used to remove excess fluid from the body during various diseases, including hypertension, heart and kidney failure, nephrotic syndrome, cirrhosis, etc. Until now, a wide range of diuretics is known, but none of them is completely safe and has a number of side effects. …”
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Prevalence of Sodium Glucose Cotransporter 2 (SGLT-2) Inhibitor Prescribing in Patients with Type 2 Diabetes Mellitus and Reduced Estimated Glomerular Filtration Rate by Kayla Chonko, Giavanna Russo-Alvarez, Diana Isaacs, Lu Wang, Amanda Soric

“… Sodium glucose cotransporter 2 (SGLT-2) inhibitors have demonstrated benefit in people with type 2 diabetes mellitus (T2DM) and chronic kidney disease (CKD), including slowing the progression of CKD and lowering the risk of kidney failure and death. Despite this evidence, literature suggests SGLT-2 inhibitors are underutilized in this population. …”
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EuroSCORE II as Predictor of Mortality and Morbidity in Post-CABG Patient in Dr. Soetomo General Academic Hospital by Rama Azalix Rianda, Bambang Pujo Semedi, Agus Subagjo, Yoppie Prim Avidar

“…Based on morbidity assessment, EuroSCORE II only accurately predicted the risk of kidney failure and did not properly assess the length of inotropic use, vasopressors, hospitalization time, the risk of arrhythmias, low cardiac output syndrome, Durante-operative bleeding, and the need for blood transfusion. …”
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Clinical features and outcomes of elderly patients with antineutrophil cytoplasmic antibody-positive vasculitis: a single-center retrospective study by Hyo Jin Kim, Miyeun Han, Sang Heon Song, Eun Young Seong

“…Oral CYC + steroid treatment was associated with decreased all-cause mortality compared to untreated induction immunosuppressants (HR, 0.01; 95% CI, 0.001–0.47; p = 0.02). Kidney failure or kidney recovery outcomes were not significantly different between the younger and elderly groups. …”
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DiaVis: Exploration and Analysis of Diabetes through Visual Interactive System by Mosiur Rahman, Md Rafiqul Islam, Sharmin Akter, Shanjita Akter, Linta Islam, Guandong Xu

“…Exploring and analyzing diabetes data is a timely concern because it may prompt a variety of serious illnesses, including stroke, kidney failure, heart attacks, etc. Several existing pieces of research have revealed that diabetes data, such as systolic blood pressure (SBP), diastolic blood pressure (DBP), weight, height, age, etc., can provide insightful information about patients diabetes states. …”
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A small-molecule inhibitor of TRPC5 ion channels suppresses progressive kidney disease in animal models by Zhou, Yiming, Castonguay, Philip, Clark, Abbe R., Dvela-Levitt, Moran, Kim, Sookyung, Sieber, Jonas, Wieder, Nicolas, Jung, Ji Yong, Andreeva, Svetlana, Reichardt, Jana, Dubois, Frank, Hoffmann, Sigrid C., Basgen, John M., Montesinos, Mónica S., Weins, Astrid, Johnson, Ashley C., Garrett, Michael R., Hopkins, Corey R., Sidhom, Eriene-Heidi I, Lander, Eric Steven, Greka, Anna

“…This scarring is due to loss of podocytes, cells critical for glomerular filtration, and leads to proteinuria and kidney failure. Inherited forms of FSGS are caused by Rac1-activating mutations, and Rac1 induces TRPC5 ion channel activity and cytoskeletal remodeling in podocytes. …”
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A cross-sectional assessment of diabetes self-management, education and support needs of Syrian refugee patients living with diabetes in Bekaa Valley Lebanon by Elliott, JA, Das, D, Cavailler, P, Schneider, F, Shah, M, Ravaud, A, Lightowler, M, Boulle, P

“…Long-term complications of diabetes most commonly known by patients were vision related complications (68% of patients), foot ulcers (39%), and kidney failure (38%). When asked about the previous Ramadan, 56% of patients stated that they undertook a full fast, including patients with type 1 diabetes. …”

Correlation of heavy metal content in water to the development of CKD in Ranau, Sabah by W.B. Chok, Baba Musta, P.Y. Moh

“…Recently, Ranau had been alarmed by a sudden spike in patients with kidney failure, reporting of 7 cases from Kg. Libang, 4 cases from Kg. …”
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Geriatric Assessment in CKD Care: An Implementation Study by Carlijn G.N. Voorend, Noeleen C. Berkhout-Byrne, Leti van Bodegom-Vos, Adry Diepenbroek, Casper F.M. Franssen, Hanneke Joosten, Simon P. Mooijaart, Willem Jan W. Bos, Marjolijn van Buren, Arjan van Alphen, Noeleen Berkhout-Byrne, Fenna van Breda, Marjolijn van Buren, Henk Boom, Willem Jan Bos, Adry Diepenbroek, Marielle Emmelot-Vonk, Casper Franssen, Carlo Gaillard, Nel Groeneweg-Peeters, Bettie Hoekstra, Nienke Hommes, Francoise Hoornaar, Hanneke Joosten, Joep Lagro, Elisabeth Litjens, Femke Molenaar, Simon Mooijaart, Aegida Neradova, Mike Peters, Michelle Troost, Wilma Veldman, Carlijn Voorend, Lidwien Westerbos, Carlijne Westerman-van der Wijden, Judith Wierdsma

“…Understanding these possibilities and challenges is crucial for improving care for older patients with kidney failure.…”
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Mathematical Modelling of Glucose-Insulin System Behaviour in Hospital Tengku Ampuan Afzan Intensive Care Unit Patients by Ummu Kulthum, Jamaludin, Fatanah, M. Suhaimi, Normy Norfiza, A. Razak, Fatimah, Dzaharudin, Azrina, M. Ralib, Mohd Basri, Mat Nor

“…Also, the glucose-insulin behaviour pattern among these 40 critically ill patients might be varied due to their main diagnotics illness such as acute kidney failure, cardiovascular disease, etc. Overall, these results might assist clinicians and researchers to understand the glucose-insulin behaviour based on patient’s severity illness and helps to inform glycaemic control protocol development in a larger group of critically ill patients.…”
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Rituximab as possible therapy in TNF inhibitor-induced IgA vasculitis with severe renal involvement by Agnieszka Przygocka, Gian Marco Berti, Anita Campus, Francesco Tondolo, Gisella Vischini, Benedetta Fabbrizio, Gaetano La Manna, Olga Baraldi

“…Combination of corticosteroids and rituximab can be an effective therapy in case of vasculitis with kidney failure and a preferable option for selected patients with drug-induced IgA vasculitis compared to cyclophosphamide. …”
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Complications associated with the use of resuscitative endovascular balloon occlusion of the aorta (REBOA): an updated review by Megan Brenner, Marcelo Augusto Fontenelle Ribeiro Junior, Salman M Salman, Sally M Al-Qaraghuli, Farah Makki, Riham A Abu Affan, Shahin Reza Mohseni

“…Systemic complications include acute kidney failure, consistently reported across various studies, with incidence rates ranging from 5.6% to 46%, representing one of the most frequently documented systemic complications. …”
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Evaluation of Comorbidities as Risk Factors for Fracture-Related Infection and Periprosthetic Joint Infection in Germany by Dominik Szymski, Nike Walter, Volker Alt, Markus Rupp

“…Mainly arterial hypertension (FRI: <i>n</i> = 3645; 50.9%—PJI: <i>n</i> = 11360; 70.2%), diabetes mellitus type II (FRI: <i>n</i> = 1483; 20.7%—PJI: <i>n</i> = 3999; 24.7%), obesity (FRI: <i>n</i> = 749; 10.5%—PJI: <i>n</i> = 3434; 21.2%) and chronic kidney failure (FRI: <i>n</i> = 877; 12.3%—PJI: <i>n</i> = 3341; 20.7%) were documented. …”
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Effect of finerenone on diabetic kidney disease outcomes with estimated glomerular filtration rate below 25 mL/min/1.73 m2 by Akira Mima, Rina Lee, Ami Murakami, Hidemasa Gotoda, Ryosuke Akai, Sayumi Kidooka, Takahiro Nakamoto, Suguru Kido, Shinji Lee

“…Background: In the Finerenone in Reducing Cardiovascular Mortality and Morbidity in Diabetic Kidney Disease trial, finerenone reduced the risk of cardiovascular events in patients with chronic kidney disease (CKD) and type 2 diabetes, while in the Finerenone in Reducing Kidney Failure and Disease Progression in Diabetic Kidney Disease trial, it improved renal and cardiovascular outcomes in patients with advanced CKD. …”
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The Quality of Randomized Controlled Trial in Cochrane Kidney and Transplant Group by Hanieh Salehi-Pourmehr, Ali Mostafaei, Amir Mehdizadeh, Sakineh Hajebrahimi, Leila Hosseini, Zahra Sheikhalipour, Nasrin Abolhasanpour

“…Cochrane systematic reviews are known for their best level of evidence. Since kidney failure is a major public health problem worldwide, the Cochrane Library provides a robust and reliable database to upgrade medical knowledge and make the best medical decisions. …”
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Macrophage-Derived Iron-Bound Lipocalin-2 Correlates with Renal Recovery Markers Following Sepsis-Induced Kidney Damage by Christina Mertens, Laura Kuchler, Anna Sola, Roser Guiteras, Stephan Grein, Bernhard Brüne, Andreas von Knethen, Michaela Jung

“…Taking into account that Lcn-2 binds and transports iron with high affinity, we aimed at clarifying if Lcn-2 fulfills different biological functions according to its iron-loading status and its cellular source during sepsis-induced kidney failure. We assessed Lcn-2 levels both in serum and in the supernatant of short-term cultured renal macrophages (MΦ) as well as renal tubular epithelial cells (TEC) isolated from either Sham-operated or cecal ligation and puncture (CLP)-treated septic mice. …”
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Cytokine response during non-cerebral and cerebral malaria: evidence of a failure to control inflammation as a cause of death in African adults by Yakhya Dieye, Babacar Mbengue, Shobha Dagamajalu, Mouhamadou Mansour Fall, Mun Fai Loke, Cheikh Momar Nguer, Alassane Thiam, Jamuna Vadivelu, Alioune Dieye

“…Regarding organ damage, kidney failure was significantly associated with death in adults suffering of cerebral malaria. …”
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Comparative evaluation of antimicrobial activity of human granulysin, bovine and porcine NK-lysins against Shiga toxin-producing Escherichia coli O157:H7. by Erika N Biernbaum, Rohana P Dassanayake, Eric M Nicholson, Indira T Kudva

“…Shiga toxin-producing Escherichia coli (STEC) O157:H7 (O157) is a foodborne pathogen causing human disease ranging from hemorrhagic colitis and hemolytic uremic syndrome to kidney failure, while remaining harmless to cattle, its primary reservoir. …”
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