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Atopy as an independent predictor for long-term patient and graft survival after kidney transplantation
Published 2022-10-01“…No significant difference was found for gender, cold/warm ischemia time, preformed donor-specific antibodies (DSA), HLA mismatches, induction and maintenance immunosuppressive therapy, CMV serostatus, or cause of kidney failure. Patient and graft survival at ten years of follow-up were significantly better in the atopic group, 95.2% versus 69.2% patient survival (P < 0.001), and 87.9% versus 60.8% graft survival (P < 0.001), respectively. …”
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1222
The dire need for improved management of chronic kidney disease – associated hypertension in Pakistan
Published 2022-03-01“… Chronic Kidney Disease (CKD) refers to various kidney disorders ranging from mild to severe chronic kidney failure. Because of its escalating incidence and mortality rates, CKD is a serious public health concern in Pakistan. …”
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1223
What are the observed procedural costs of vascular access surgery? Protocol for a systematic review
Published 2024-01-01“…The treatment of kidney failure requires a significant volume of resources, and vascular access provision is the main modifiable cost. …”
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1224
Conventional Biological versus Sutureless Aortic Valve Prostheses in Combined Aortic and Mitral Valve Replacement
Published 2023-03-01“…There was no significant difference in the occurrence of postoperative major adverse events such as death, stroke, myocardial infarction and kidney failure between the groups. There was also no significant difference in the permanent pacemaker implantation rate, paravalvular leakage or valve dislocation. …”
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1225
Evaluation of Vancomycin Resistant Enterecoccal Infections
Published 2022-03-01“…The most common risk factors in patients were advanced age, urinary and central venous catheters, acute kidney injury or chronic kidney failure. The use of glycopeptides before VRE infection was 42.85%, and 100% of patients had previously used 3rd generation cephalosporins.Conclusion:The more important the isolation, correct identification and determination of antibiotic susceptibility in the infections caused by enterococci, the more vital it is to monitor the antibiotic susceptibility profiles for these bacteria.…”
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1226
Cerebellar infarction risk in a mild COVID-19 case
Published 2023-02-01“…Thrombotic events in SARS-COV-2 disease patients are frequent, especially in patients with comorbidities such as heart failure, hypertension, cancer, diabetes mellitus, kidney failure, vascular disease, and other pulmonary illnesses. …”
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1227
Alternatively Spliced Landscape of PPARγ mRNA in Podocytes Is Distinct from Adipose Tissue
Published 2022-11-01“…Podocytes are highly differentiated epithelial cells, and their structural and functional integrity is compromised in a majority of glomerular and renal diseases, leading to proteinuria, chronic kidney disease, and kidney failure. Traditional agonists (e.g., pioglitazone) and selective modulators (e.g., GQ-16) of peroxisome-proliferator-activated-receptor-γ (PPARγ) reduce proteinuria in animal models of glomerular disease and protect podocytes from injury via PPARγ activation. …”
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1228
Potential Effects of Sweet Potato (<i>Ipomoea batatas</i>) in Hyperglycemia and Dyslipidemia—A Systematic Review in Diabetic Retinopathy Context
Published 2021-10-01“…Numerous drugs have been approved by officials to treat these conditions, but usage of any synthetic drugs in the long term will result in unavoidable side effects such as kidney failure. Therefore, more emphasis is being placed on natural ingredients due to their bioavailability and absence of side effects. …”
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1229
The Impact of Nutritional Status on Sexual Function in Male Kidney Transplant Recipients
Published 2023-02-01“…<i>Materials and Methods</i><span style="font-variant: small-caps;">:</span> Fifty-four men with kidney failure who had undergone replacement therapy entered the study. …”
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1230
Cell surface GRP78 regulates TGFβ1-mediated profibrotic responses via TSP1 in diabetic kidney disease
Published 2023-02-01“…Introduction: Diabetic kidney disease (DKD) is the leading cause of kidney failure in North America, characterized by glomerular accumulation of extracellular matrix (ECM) proteins. …”
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1231
eGFRcystatinC/eGFRcreatinine ratio < 0.6 in patients with SARS-CoV-2 pneumonia: a prospective cohort study
Published 2023-09-01“…Factors that influence this ratio are complex and, in addition to the possible shrinkage of pores, other conditions such as thickening of glomerular basal membrane, comorbidities, prerenal kidney failure and others may play an important role and should be addressed when diagnosing SPS. …”
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1232
Advances in Membranous Nephropathy
Published 2021-02-01“…MN is the most common cause of nephrotic syndrome in adults leading to severe thrombotic complications and kidney failure. This review is focused on the recent therapeutic and pathophysiological advances that occurred in the last two years. …”
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1233
WHY BETA-BLOCKERS ARE NOT PRESCRIBED TO PATIENTS WITH HEART FAILURE AND HOW TO IMPROVE IT?
Published 2016-01-01“…The highest refractoriness to CHF therapy was in patients with chronic kidney failure, atrial fibrillation and anemia (odds efficiency was 2.2, 2.9 and 3.1%, respectively). …”
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1234
Death and Dialysis Following Discharge From Chronic Kidney Disease Clinic: A Retrospective Cohort Study
Published 2022-08-01“…In Ontario, Canada, the eligibility criteria for multidisciplinary CKD care funding were revised between 2016 and 2018 to a 2 year risk of kidney replacement therapy (KRT) greater than 10% calculated by the 4-variable Kidney Failure Risk Equation (KFRE). Implementation of the risk-based approach has led to the discharge of prevalent CKD patients. …”
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1235
Urinary Prostaglandin E2 Excretion and the Risk of Cardiovascular and Kidney Disease
Published 2024-02-01“…Longitudinal associations with cardiovascular mortality and kidney outcomes (eGFR <60 or <45 mL/min per 1.73 m2 and the composite outcome 40% eGFR loss or kidney failure) were assessed with Cox regression. Urinary PGE2 and PGEM excretions were higher with increasing age, lower eGFR, smoking, diabetes, and albuminuria. …”
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1236
Big data analytics for MerTK genomics reveals its double-edged sword functions in human diseases
Published 2024-04-01“…Finally, based on our proteomics from primary human aortic ECs, we validated the functions of MerTK in several human diseases, such as cancer, aging, kidney failure and heart failure. Conclusions: Our big data analytics suggest that MerTK may be a promising therapeutic target, but how it should be modulated depends on the disease types and sex differences. …”
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1237
Lysozyme promotes renal fibrosis through the JAK/STAT3 signal pathway in diabetic nephropathy
Published 2023-07-01“…Introduction Diabetic nephropathy (DN) is a leading cause of kidney failure. Lysozyme (LYZ) is an essential component of innate immunity and exhibits antibacterial properties. …”
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1238
Use of T1 mapping in cardiac MRI for the follow-up of Fabry disease in a pediatric population
Published 2024-03-01“…Life threatening complications in adulthood include chronic kidney failure, strokes and the cardiac involvement which is the leading cause of mortality. …”
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1239
Trends in nephrology referral patterns for patients with chronic kidney disease: Retrospective cohort study.
Published 2022-01-01“…The guideline concordant cohort were more likely to be on renin-angiotensin system blockers or beta blockers (hazard ratio 1.14, 95% confidence interval 1.12, 1.16), and had a higher risk of CKD progression (hazard ratio 1.09, 95% confidence interval 1.06, 1.13), kidney failure (hazard ratio 7.65, 95% confidence interval 6.83, 8.56), cardiovascular event (hazard ratio 1.40, 95% confidence interval 1.35,1.45) and mortality (hazard ratio 1.58, 95% confidence interval 1.52, 1.63).…”
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1240
Renal‐hepatic‐pancreatic dysplasia type 2: Perinatal lethal condition or a multisystemic disorder with variable expressivity
Published 2023-04-01“…Of the four cases living past the first year of life, one case died at 5 years secondary to renal failure, the other at 30 months secondary to liver and kidney failure. Two are currently alive and well at one year and 13 years. …”
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