Evaluation of the efficacy of cystinosin supplementation through CTNS mRNA delivery in experimental models for cystinosis by Tjessa Bondue, Sante Princiero Berlingerio, Florian Siegerist, Elena Sendino-Garví, Maximilian Schindler, Hans Jacobus Baelde, Sara Cairoli, Bianca Maria Goffredo, Fanny Oliveira Arcolino, Jürgen Dieker, Manoe Jacoba Janssen, Nicole Endlich, Roland Brock, Rik Gijsbers, Lambertus van den Heuvel, Elena Levtchenko

“…The kidneys are the first and the most severely affected organs, presenting glomerular and proximal tubular dysfunction, progressing to end-stage kidney failure. The current therapeutic standard cysteamine, reduces cystine levels, but has many side effects and does not restore kidney function. …”
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Emerging trends of phytochemicals as ferroptosis modulators in cancer therapy by Fahad Khan, Pratibha Pandey, Meenakshi Verma, Seema Ramniwas, Dain Lee, Seungjoon Moon, Moon Nyeo Park, Tarun Kumar Upadhyay, Bonglee Kim

“…Ferroptosis, a novel form of regulated cell death characterized by dependence on iron and lipid peroxidation, has been implicated in a wide range of clinical conditions including neurological diseases, cardiovascular disorders, acute kidney failure, and various types of cancer. Therefore, it is critical to suppress cancer progression and proliferation. …”
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Chronic Kidney Disease Care in Indonesia: Challenges and Opportunities by Ni Made Hustrini

“…We can argue this statement with evidence from the tertiary care, where it was reported that most kidney failure patients (83%) commenced dialysis with an urgent start, along with late referral to nephrologist (90%), started dialysis with temporary catheter (95.2%), and the median eGFR to start dialysis was 5.3 (range: 0.6 – 14.6) ml/minute/1.73 m2. …”
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Clinical characteristics of COVID-19 hospitalized patients associated with mortality: A cohort study in Spain by Manuel Lozano, Adina Iftimi, Alvaro Briz-Redon, Juanjo Peiró, Lara Manyes, María Otero, Mayte Ballester, M. Dolores de las Marinas, Juan Carlos Catalá, José de Andrés, Carolina Romero

“…Results: We observed that cough and kidney failure triplicate the mortality risk and both bilirubin levels and oncologic condition are shown as the most associated with the demise, increasing in four and ten times the risk, respectively. …”
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Cardiovascular and kidney outcomes of uric acid-lowering therapy in patients with different kidney functions: study protocol for a systematic review, pairwise and network meta-anal... by Lihua Wang, Yaqing Zhang, Xiaole Su, Ying Hua, Runxia Song

“…Primary outcomes will be the occurrence of major cardiovascular events and kidney failure events. Secondary outcomes will include the rate of change in eGFR per year, all-cause death, changes in serum uric acid level and major adverse events. …”
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Anemia of Chronic Diseases: Wider Diagnostics—Better Treatment? by Michał Wiciński, Grzegorz Liczner, Karol Cadelski, Tadeusz Kołnierzak, Magdalena Nowaczewska, Bartosz Malinowski

“…This disease most often coexists with chronic inflammation, autoimmune diseases, cancer, and kidney failure. Before starting treatment, one should undertake in-depth diagnostics, which includes not only assessment of complete blood count and biochemical parameters, but also severity of the underlying disease. …”
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Acute Kidney Injury with SARS-CoV-2 Infection in Pediatric Patients Receiving High-Dose Methotrexate Chemotherapy: A Report of Three Cases by Olga Nigro, Cristina Meazza, Elisabetta Schiavello, Veronica Biassoni, Nadia Puma, Luca Bergamaschi, Giovanna Gattuso, Giovanna Sironi, Virginia Livellara, Gabriele Papagni, Maura Massimino

“…Therefore, we wondered whether our patients’ kidney failure might have been triggered by their underlying SARS-CoV-2 positivity. …”
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Predictors for short-term successful weaning from continuous renal replacement therapy: a systematic review and meta-analysis by Yu Li, Xiaoqi Deng, Jiaxing Feng, Bo Xu, Yulei Chen, Zhanying Li, Xiaodan Guo, Tianjun Guan

“…Our criteria included patients with AKI who required CRRT but excluded patients with kidney failure. The pooled odds ratios (OR) and 95% confidence intervals (CI) were calculated using fixed-effect (I2≤50% and P-value of the Q statistic > 0.1) or random-effect models (I2>50% or p-value of the Q statistic ≤ 0.1) as appropriate. …”
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Development and evaluation of glucose-responsive biomaterials as self-regulated insulin delivery systems by Volpatti, Lisa Rae.

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Gluconeogenesis as a system : development of in vivo flux analysis of hepatic glucose production in Type 2 Diabetes by Alemán, José O. (José Orlando)

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Gender and vulnerable types among vulnerable member in Malaysia fisheries and aquaculture community by Zainalaludin, Zumilah, Jamaluddin, Askiah, Abd Shukor, Suryati, Saidi, Norehan

“…Initially, eight conceptual definitions obtained in literatures on economically vulnerable due to poverty and disable to work and earn income – i) older person, ii) poor single mother/father, iii) handicapped person, iv) career of bed ridden patient, v) suffering of serious illness (diabetic, heart problem, kidney failure, hypertension, and cancer), vi) poor and living alone, vii) child labor, and viii) others. …”
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Treatment Adherence in CKD and Support From Health care Providers: A Qualitative StudyPlain-Language Summary by Eleanor Rivera, Maya N. Clark-Cutaia, Sarah J. Schrauben, Raymond R. Townsend, James P. Lash, Mary Hannan, Bernard G. Jaar, Hernan Rincon-Choles, Sheru Kansal, Jiang He, Jing Chen, Karen B. Hirschman

“…Rationale & Objective: Adherence to recommended medical treatment is critical in chronic kidney disease (CKD) to prevent complications and progression to kidney failure. Overall adherence to treatment is low in CKD, and as few as 40% of patients with kidney failure receive any documented CKD-related care. …”
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The need for kidney biopsy in the management of side effects of target and immunotherapy by Roberta Fenoglio, Martina Cozzi, Giulio Del Vecchio, Savino Sciascia, Antonella Barreca, Alessandro Comandone, Dario Roccatello

“…Histological evaluations of kidney disorders induced by targeted/immunotherapy are limited.MethodIn this study we examined the histological features of patients treated with new cancer agents who underwent a kidney biopsy for new onset kidney failure and/or urinary abnormalities.ResultsThe cohort included 30 adult patients. …”
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Far-Infrared Therapy Decreases Orthotopic Allograft Transplantation Vasculopathy by Yi-Wen Lin, Chien-Sung Tsai, Chun-Yao Huang, Yi-Ting Tsai, Chun-Ming Shih, Shing-Jong Lin, Chi-Yuan Li, Cheng-Yen Lin, Shih-Ying Sung, Feng-Yen Lin

“…Orthotopic allograft transplantation (OAT) is a major strategy for solid heart and kidney failure. However, the recipient’s immunity-induced chronic rejection induces OAT vasculopathy that results in donor organ failure. …”
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Unpacking Phthalates from Obscurity in the Environment by Marzieh Baneshi, Jamey Tonney-Gagne, Fatima Halilu, Kavya Pilavangan, Ben Sabu Abraham, Ava Prosser, Nikaran Kanchanadevi Marimuthu, Rajendran Kaliaperumal, Allen J. Britten, Martin Mkandawire

“…It is now known that they can potentially impact ecological and human health adversely, leading to their categorization as endocrine-disrupting chemicals, carcinogenic, and liver- and kidney-failure-causing agents, which has landed them among contaminants of emerging concern (CECs). …”
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Does Ganoderma lucidum reduce obesity? by Ameneh Marzban, Abdolrazagh Marzban, Payam Emami

“…In this case, consuming Ganoderma fungus helps the patient takes less medicine by strengthening and regulating the immune system, leading to weight loss (4). Kidney failure, heart disease, and heart problems cause excess water to build up in the body. …”
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Relationship between self-care compliance, trust, and satisfaction among hypertensive patients in China by Chi Zhou, Jingchun Chen, Fang Tan, Sihong Lai, Xu Li, Ke Pu, Jiahui Wu, Yin Dong, Falin Zhao

“…It is a leading risk factor for all-cause mortality and may lead to complications such as cardiovascular disease, stroke, and kidney failure. Poor compliance of hypertensive patients is one of the major barriers to controlling high blood pressure. …”
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Simplified Iohexol-Based Method for Measurement of Glomerular Filtration Rate in Goats and Pigs by Maaike K. van Gelder, Jasper Stevens, Tobias T. Pieters, Koen R. D. Vaessen, Jaap A. Joles, Marianne C. Verhaar, Karin G. F. Gerritsen

“…An intravenous bolus of iohexol was administered to goats (13 measurements in <i>n</i> = 3 goats) and pigs (23 measurements in <i>n</i> = 5 pigs) before and after induction of kidney failure, followed by frequent blood sampling up to 1440 min. …”
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Prognostic Value of Machine Learning in Patients with Acute Myocardial Infarction by Changhu Xiao, Yuan Guo, Kaixuan Zhao, Sha Liu, Nongyue He, Yi He, Shuhong Guo, Zhu Chen

“…(1) Background: Patients with acute myocardial infarction (AMI) still experience many major adverse cardiovascular events (MACEs), including myocardial infarction, heart failure, kidney failure, coronary events, cerebrovascular events, and death. …”
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Central Oxygen Venous Saturation and Mortality in Patients Undergoing Coronary Artery Bypass Grafting by Rodríguez-Scarpetta MA, Sepúlveda-Tobón AM, Daza-Arana JE, Lozada-Ramos H, Álzate-Sánchez RA

“…Values were adjusted using variables such as age (> 75 years), low socioeconomic stratum, chronic kidney failure before surgery, unstable angina before surgery, ischemia time (> 60 min), and intra-operative inotrope use. …”
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