CSI clinical practice guidelines for dyslipidemia management: Executive summary by Jitendra PS. Sawhney, Sivasubramanian Ramakrishnan, Kushal Madan, Saumitra Ray, P Balagopalan Jayagopal, Dorairaj Prabhakaran, Tiny Nair, Geevar Zachariah, Peeyush Jain, Jamshed Dalal, Sitaraman Radhakrishnan, Arun Chopra, Sanjay Kalra, Ashwani Mehta, Arvind K. Pancholia, Nitin K. Kabra, Dhiman Kahali, Tapan Ghose, Satyavir Yadav, Prafulla Kerkar, Ajay Yadav, Debabrata Roy, Mrinal Kanti Das, Vijay H. Bang, Pratap Chandra Rath, Dhurjati Prasad Sinha, P.S. Banerjee, Rakesh Yadav, Rajeev Gupta

“…Management of dyslipidemias in oft-neglected patient phenotypes-the elderly, young and children, and patients with comorbidities-stroke, peripheral arterial disease, kidney failure, posttransplant, HIV (Human immunodeficiency virus), Covid-19 and familial hypercholesterolemia is also presented. …”
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Epidemiology and Outcomes of AKI Treated With Continuous Kidney Replacement Therapy: The Multicenter CRRTnet StudyPlain Language Summary by Oleksa G. Rewa, Victor Ortiz-Soriano, Joshua Lambert, Shaowli Kabir, Michael Heung, Andrew A. House, Divya Monga, Luis A. Juncos, Michelle Secic, Robin Piazza, Stuart L. Goldstein, Sean M. Bagshaw, Javier A. Neyra

“…Patients with pre-existing kidney failure and those with coronavirus 2 infection were excluded. …”
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Hospitalizations for tuberculosis in Sicily over the years 2009–2021: Clinical features, comorbidities, and predictors of mortality by Luca Pipitò, Claudia Colomba, Alessandro Mancuso, Bianca Catania, Alessandra Cuccia, Maria Sergio, Chiara Iaria, Antonio Cascio

“…Multivariate analysis showed that the development of acute kidney failure (adjusted odds ratio [aOR]=7.2, p < 0.001), alcohol consumption (aOR=8.9, p = 0.001), malignant tumors (aOR=2.1, p = 0.022), human immunodeficiency virus infection (aOR=3.4, p < 0.001), sepsis (aOR=15.2, p < 0.001), central nervous system involvement (aOR=9.9, p < 0.001), and miliary TB (aOR=2.5, p = 0.004) were independent predictors of mortality. …”
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Plant-Dominant Low-Protein Diet for Conservative Management of Chronic Kidney Disease by Kamyar Kalantar-Zadeh, Shivam Joshi, Rebecca Schlueter, Joanne Cooke, Amanda Brown-Tortorici, Meghan Donnelly, Sherry Schulman, Wei-Ling Lau, Connie M. Rhee, Elani Streja, Ekamol Tantisattamo, Antoney J. Ferrey, Ramy Hanna, Joline L.T. Chen, Shaista Malik, Danh V. Nguyen, Susan T. Crowley, Csaba P. Kovesdy

“…Government Executive Order seek to implement strategies that reduce the burden of kidney failure by slowing CKD progression and controlling uremia without dialysis. …”
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COVID-19 in China and the US: Differences in Hospital Admission Co-Variates and Outcomes by Yulin Cao, Di Wu, Kuo Zeng, Lei Chen, Jianming Yu, Wenjuan He, Li Chen, Wenxiang Ren, Fei Gao, Wenlan Chen, Hongxiang Wang, Robert Peter Gale, Zhichao Chen, Qiubai Li

“…Wuhan subjects had higher blood nadir median lymphocyte concentrations and longer hospitalizations, and were less likely to receive IMV, ICU hospitalization, and interventions for kidney failure. Amongst subjects not receiving IMV, those in Wuhan were less likely to die compared with New York subjects. …”
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Empagliflozin and Rapid Kidney Function Decline Incidence in Type 2 Diabetes: An Exploratory Analysis From the EMPA-REG OUTCOME Trial by Samy Hadjadj, Mark E. Cooper, Dominik Steubl, Michaela Petrini, Stefan Hantel, Michaela Mattheus, Christoph Wanner, Merlin C. Thomas

“…Many develop progressive chronic kidney disease (CKD), but some experience a more rapid decline, with a greater risk of kidney failure and cardiovascular disease. In EMPA-REG OUTCOME, empagliflozin was associated with slower kidney disease progression. …”
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Polyethersulfone mixed matrix membrane containing imprinted zeolite for cresol removal in hemodialysis application by Raharjo, Yanuardi

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Impact of diabetes on the effects of sodium glucose co-transporter-2 (SGLT2) inhibitors on kidney outcomes: collaborative meta-analysis of large placebo-controlled trials by Herrington, W, Staplin, N, Haynes, R, Mayne, K, Roddick, A, Landray, M, Baigent, C, Preiss, D, Judge, P, Emberson, J

“…The main efficacy outcomes were kidney disease progression (standardised to a definition of a sustained ≥50% decrease in estimated glomerular filtration rate [eGFR] from randomisation, a sustained low eGFR, end-stage kidney disease, or death from kidney failure), acute kidney injury, and a composite of cardiovascular death or hospitalisation for heart failure. …”

Platinum Nanodendrites Modified Electrode For Lead (Pb) Detection by RamlI, Nurul Hidayah

“…. _______________________________________________________________________ Heavy metal pollution in the environment has caused accumulation of heavy metal ions in the food chain and this has led to serious health issues for humans such as brain injury and kidney failure. Thus, the detection of heavy metal is important. …”
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Polyethersulfone mixed matrix membrane containing imprinted zeolite for cresol removal in hemodialysis application by Raharjo, Yanuardi

“…The adequacy of uremic toxins removal on hemodialysis treatment is essential to be achieved for kidney failure disease patient, as poor removal leads to heart failure, hypertension, and stroke. …”
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Rethinking Figurative Language in the Rhetoric of Healthcare Allocation by Brian Li, Marta Napiorkowska

“…Some physicians might call a person a “vegetable” or invite residents to examine “the kidney failure down the hall.” In the former example, “vegetable” makes the abstractness of a disorder of consciousness into a potentially derogatory colloquialism. …”
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Organic Pollutant Exposure and CKD: A Chronic Renal Insufficiency Cohort Pilot Study by David M. Charytan, Wenbo Wu, Mengling Liu, Zhong-Min Li, Kurunthachalam Kannan, Leonardo Trasande, Vineet Kumar Pal, Sunmi Lee, Howard Trachtman, Lawrence J. Appel, MD, MPH, Jing Chen, MD, MMSc, MSc, Debbie L. Cohen, MD, Harold I. Feldman, MD, MSCE, Alan S. Go, MD, James P. Lash, MD, Robert G. Nelson, MD, PhD, MS, Mahboob Rahman, MD, Panduranga S. Rao, MD, Vallabh O. Shah, PhD, MS, Mark L. Unruh, MD, MS.

“…Outcomes: The outcomes were as follows: death; composite of congestive heart failure, myocardial infarction, and stroke; event-free survival from kidney failure or ≥50% decline in estimated glomerular filtration rate (eGFR); and longitudinal trajectory of eGFR. …”
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Sexual dimorphic response to rituximab treatment: A longitudinal observational study in a large cohort of patients with primary membranous nephropathy and persistent nephrotic synd... by Annalisa Perna, Barbara Ruggiero, Manuel Alfredo Podestà, Manuel Alfredo Podestà, Luca Perico, Silvia Orisio, Hanna Debiec, Giuseppe Remuzzi, Piero Ruggenenti, Piero Ruggenenti

“…Rituximab is one of the first-line therapies for patients with membranous nephropathy (MN) at high risk of progression towards kidney failure. We investigated whether the response to Rituximab was affected by sex and anti-PLA2R antibody levels in 204 consecutive patients (148 males and 56 females) with biopsy-proven MN who were referred to the Nephrology Unit of the Azienda Socio Sanitaria Territoriale Papa Giovanni XXIII from March 2001 to October 2016 and managed conservatively for at least 6 months. …”
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In Vitro Evaluation of α-amylase and α-glucosidase Inhibition of 2,3-Epoxyprocyanidin C1 and Other Constituents from <i>Pterocarpus erinaceus</i> Poir by Romeo Toko Feunaing, Alfred Ngenge Tamfu, Abel Joel Yaya Gbaweng, Larissa Mekontso Magnibou, Fidele Ntchapda, Celine Henoumont, Sophie Laurent, Emmanuel Talla, Rodica Mihaela Dinica

“…Chronic diabetes can lead to kidney failure, blindness, limb amputation, heart attack and stroke. …”
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Can regulatory T cells improve outcomes of sensitised patients after HLA-Ab incompatible renal transplantation: study protocol for the Phase IIa GAMECHANgER-1 trial by C Dudreuilh, P Jarvis, N Beadle, I Pilecka, O Shaw, L Gardner, C Scottà, N Mamode, DS Game, A Sanchez-Fueyo, G Lombardi, A Learoyd, A Douiri, A Dorling

“…Abstract Background Kidney transplantation is the gold-standard treatment for patients with kidney failure. However, one-third of patients awaiting a kidney transplant are highly sensitized to human leukocyte antigens (HLA), resulting in an increased waiting time for a suitable kidney, more acute and chronic rejection, and a shorter graft survival compared to non-highly sensitised patients. …”
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Antigenic mapping and functional characterization of human New World hantavirus neutralizing antibodies by Taylor B Engdahl, Elad Binshtein, Rebecca L Brocato, Natalia A Kuzmina, Lucia M Principe, Steven A Kwilas, Robert K Kim, Nathaniel S Chapman, Monique S Porter, Pablo Guardado-Calvo, Félix A Rey, Laura S Handal, Summer M Diaz, Irene A Zagol-Ikapitte, Minh H Tran, W Hayes McDonald, Jens Meiler, Joseph X Reidy, Andrew Trivette, Alexander Bukreyev, Jay W Hooper, James E Crowe

“…There are currently no FDA-approved vaccines or therapeutics for hantaviruses, and the only treatment for infection is supportive care for respiratory or kidney failure. Additionally, the human humoral immune response to hantavirus infection is incompletely understood, especially the location of major antigenic sites on the viral glycoproteins and conserved neutralizing epitopes. …”
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Cardiovascular and Mortality Risks in Young Health Screening Examinees With Marginal Estimated GFR by Minsang Kim, Kyungdo Han, Kwon Wook Joo, Jeong Min Cho, Soojin Lee, Yaerim Kim, Semin Cho, Hyuk Huh, Seong Geun Kim, Eunjeong Kang, Dong Ki Kim, Sehoon Park

“…We included young adults aged 20–39 years without a history of major adverse cardiovascular events (MACE) or kidney failure, who underwent nationwide health screening in 2012. …”
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DNA Methylation-Based Prediction of Post-operative Atrial Fibrillation by Matthew A. Fischer, Aman Mahajan, Maximilian Cabaj, Todd H. Kimball, Marco Morselli, Elizabeth Soehalim, Douglas J. Chapski, Dennis Montoya, Colin P. Farrell, Jennifer Scovotti, Claudia T. Bueno, Naomi A. Mimila, Richard J. Shemin, David Elashoff, David Elashoff, Matteo Pellegrini, Emma Monte, Thomas M. Vondriska, Thomas M. Vondriska, Thomas M. Vondriska

“…BackgroundAtrial fibrillation (AF) is the most common sustained cardiac arrhythmia and post-operative atrial fibrillation (POAF) is a major healthcare burden, contributing to an increased risk of stroke, kidney failure, heart attack and death. Genetic studies have identified associations with AF, but no molecular diagnostic exists to predict POAF based on pre-operative measurements. …”
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The Impact of Kidney Biopsy for Fabry Nephropathy Evaluation on Patients’ Management and Long-Term Outcomes: Experience of a Single Center by Elena-Emanuela Rusu, Diana-Silvia Zilisteanu, Lucia-Mihaela Ciobotaru, Mihaela Gherghiceanu, Alexandru Procop, Ruxandra-Oana Jurcut, Adriana Octaviana Dulamea, Bogdan Marian Sorohan

“…We defined a combined endpoint as being at least one of the following: 50% decrease of estimated glomerular filtration rate (eGFR) from baseline, kidney failure (KF), end-stage kidney disease (ESKD), or death and mortality. …”
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Associations of Diet with Urinary Trimethylamine-N-Oxide (TMAO) and Its Precursors among Free-Living 10-Year-Old Children: Data from SMBCS by Yiming Dai, Jiming Zhang, Zheng Wang, Sinan Xu, Qinyu Zhang, Zhiping Duan, Ruonan Tan, Xiaojuan Qi, Jianqiu Guo, Xiuli Chang, Chunhua Wu, Zhijun Zhou

“…Trimethylamine-N-oxide (TMAO), a diet-derived cometabolite linked to cardiometabolic disease, has been associated with elevated dietary status, particularly in people with kidney failure and adults with dietary modulations. However, the influence of the current diet on TMAO levels in free-living children has not been adequately described. …”
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