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481
Gene Expression and Photophysiological Changes in <i>Pocillopora acuta</i> Coral Holobiont Following Heat Stress and Recovery
Published 2020-08-01“…Significant changes in gene expression levels of selected genes of interest (GOI) were observed following heat exposure and stress removal among sites and colonies, including <i>Actin</i>, calcium/calmodulin-dependent protein kinase type IV (<i>Camk4</i>), kinesin-like protein (<i>KIF9</i>), and small heat shock protein 16.1 (<i>Hsp16.1</i>). …”
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482
Zebrafish homologs of 16p11.2, a genomic region associated with brain disorders, are active during brain development, and include two deletion dosage sensor genes
Published 2012“…In a screen for 16p11.2 genes whose function is sensitive to hemizygosity, the aldolase a (aldoaa) and kinesin family member 22 (kif22) genes were identified as giving clear phenotypes when RNA levels were reduced by ~50%, suggesting that these genes are deletion dosage sensors. …”
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483
Angiomotin isoform 2 promotes binding of PALS1 to KIF13B at primary cilia and regulates ciliary length and signaling
Published 2023“…The kinesin-3 motor KIF13B functions in endocytosis, vesicle transport and regulation of ciliary length and signaling. …”
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484
Physiological and molecular effects of gibberellic acid and paclobutrazol on young clonal palm growth and development
Published 2021“…Higher expression of the growth suppressor RCC and two- to eight-fold lower expression of cytoskeletal motor genes actin 3 and kinesin 3, cellulose synthase CESA2, pectin activator WAK3 and pectin lyase-like suggested that PBZ may suppressed cell expansion in leaves by enhancing secondary cell wall rigidity in oil palm. …”
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485
Transcriptome and metabolome analyses reveal the key genes related to grain size of big grain mutant in Tartary Buckwheat (Fagopyrum tartaricum)
Published 2022-12-01“…Using a combined comprehensive analysis, we identified 24 potential candidate genes that encode E3 ubiquitin-protein ligase HIP1, EMBRYO-DEFECTIVE (EMB) protein, receptor-like protein kinase FERONIA (FER), kinesin-4 protein SRG1, and so on, which may be associated with the big-grain mutant bg1. …”
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486
Circular RNA circ_0010235 sponges miR-338-3p to play oncogenic role in proliferation, migration and invasion of non-small-cell lung cancer cells through modulating KIF2A
Published 2021-01-01“…Here, we intended to investigate role and mechanism of circ_0010235 in NSCLC proliferation, migration and invasion.Methods and results Expression of circ_0010235, microRNA (miR)-338-3p and kinesin family member 2A (KIF2A) was detected by quantitative real-time PCR, western blotting and immunohistochemistry (IHC). …”
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487
Cascading effects of hypobaric hypoxia on the testis: insights from a single-cell RNA sequencing analysis
Published 2023-11-01“…Hypobaric hypoxia downregulates the genes controlling granule secretion and organic matter biosynthesis, upregulates tektin 1 (TEKT1) and kinesin family member 2C (KIF2C), and downregulates 60S ribosomal protein 11 (RPL11) and cilia- and flagella-associated protein 206 (CFAP206). …”
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488
EGFR‐mediated hyperacetylation of tubulin induced docetaxel resistance by downregulation of HDAC6 and upregulation of MCAK and PLK1 in prostate cancer cells
Published 2024-01-01“…PC/DX25 with greater resistance to docetaxel had higher levels of acetyl‐tubulin and mitotic centromere‐associated kinesin (MCAK) than PC3 cells. This study found that docetaxel induced the expression of acetyl‐tubulin and MCAK in PC3 cells at a dose‐ and time‐dependent manner. …”
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489
KIF5B plays important roles in dendritic spine plasticity and dendritic localization of PSD95 and FMRP in the mouse cortex in vivo
Published 2024-03-01“…Summary: Kinesin 1 (KIF5) is one major type of motor protein in neurons, but its members’ function in the intact brain remains less studied. …”
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490
Mechanism of miR‐424‐5p promoter methylation in promoting epithelial–mesenchymal transition of hepatocellular carcinoma cells
Published 2022-04-01“…Dual‐luciferase reporter assay further validated that miR‐424‐5p bound to the kinesin family member 2A (KIF2A), and miR‐424‐5p overexpression downregulated KIF2A. …”
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491
TRAF4 Inhibits the Apoptosis and Promotes the Proliferation of Breast Cancer Cells by Inhibiting the Ubiquitination of Spindle Assembly-Associated Protein Eg5
Published 2022-05-01“…By studying the relationship between TRAF4 and Eg5, a member of the kinesin family that plays a critical role in spindle assembly, we demonstrated that TRAF4 regulated Eg5 ubiquitination and contributed to Eg5-mediated breast cancer proliferation and inhibited breast cancer apoptosis. …”
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492
Bioinformatical analysis of the key differentially expressed genes for screening potential biomarkers in Wilms tumor
Published 2023-09-01“…Top 12 genes were identified for further study after constructing a PPI network and screening hub gene modules. Kinesin family member 2C (KIF2C) was identified as the most significant gene predicting the overall survival of WT patients. …”
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493
Harnessing axonal transport to map reward circuitry: Differing brain-wide projections from medial prefrontal cortical domains
Published 2023-11-01“…Mn(II), a contrast agent for MRI, enters neurons through voltage-activated calcium channels and relies on kinesin-1 and amyloid-precursor protein to transport out axons to distal destinations. …”
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494
Association of variants in the KIF1A gene with amyotrophic lateral sclerosis
Published 2022-10-01“…Notably, sensory and motor neuron diseases such as hereditary sensory and autonomic neuropathy type 2 (HSAN2) and spastic paraplegia 30 (SPG30) share several causative genes with ALS, as well as having common clinical phenotypes. KIF1A encodes a kinesin 3 motor that transports presynaptic vesicle precursors (SVPs) and dense core vesicles and has been reported as a causative gene for HSAN2 and SPG30. …”
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495
Genome-wide analyses identify KIF5A as a novel ALS gene
Published 2018“…Through both approaches, we identified kinesin family member 5A (KIF5A) as a novel gene associated with ALS. …”
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496
Single-cell transcriptomics reveals the role of Macrophage-Naïve CD4 + T cell interaction in the immunosuppressive microenvironment of primary liver carcinoma
Published 2022-10-01“…Based on the MNT score, five relevant drugs (inhibitor of polo-like kinase 1, inhibitor of kinesin family member 11, dabrafenib, ispinesib, and epothilone-b) were predicted. …”
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497
KIF2C promotes clear cell renal cell carcinoma progression via activating JAK2/STAT3 signaling pathway
Published 2023-12-01“…Recently, more attention was paid to the functions of Kinesin family member 2C (KIF2C) in cancer progression, while the specific function of KIF2C in ccRCC has not been sufficiently elucidated. …”
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498
Cell cycle dysregulation with overexpression of KIF2C/MCAK is a critical event in nasopharyngeal carcinoma
Published 2023-01-01“…Protein–protein interaction (PPI) network analysis identified a 15 hub-gene core network with overexpressed kinesin family member 2C (KIF2C) as a central regulator. …”
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499
Comprehensive Pan-Cancer Analysis of KIF18A as a Marker for Prognosis and Immunity
Published 2023-02-01“…KIF18A belongs to the Kinesin family, which participates in the occurrence and progression of tumors. …”
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500
TPX2 enhances the transcription factor activation of PXR and enhances the resistance of hepatocellular carcinoma cells to antitumor drugs
Published 2023-01-01“…The target protein for the Xenopus plus end-directed kinesin-like protein (Xklp2) known as TPX2 that was previously considered as a tubulin regulator, also functions as the regulator of some transcription factors and pro-oncogenes in human malignances. …”
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