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Kinesin-1 Regulates Extrasynaptic Targeting of NMDARs and Neuronal Vulnerability Toward Excitotoxicity
Published 2019-03-01“…Here, we report that the reduction of Kif5b, the heavy chain of kinesin-1, protected neurons against NMDA-induced excitotoxicity and ischemia-provoked neurodegeneration. …”
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62
TRIM3 regulates the motility of the kinesin motor protein KIF21B.
Published 2013-01-01“…Kinesin superfamily proteins (KIFs) are molecular motors that transport cellular cargo along the microtubule cytoskeleton. …”
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63
Motor Skills: Recruitment of Kinesins, Myosins and Dynein during Assembly and Egress of Alphaherpesviruses
Published 2021-08-01Subjects: Get full text
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64
Motility and microtubule depolymerization mechanisms of the Kinesin-8 motor, KIF19A
Published 2016-09-01Subjects: “…kinesin…”
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65
Competition between kinesin-1 and myosin-V defines Drosophila posterior determination
Published 2020-02-01Subjects: “…kinesin…”
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66
Kinesin Motors in the Filamentous Basidiomycetes in Light of the <i>Schizophyllum commune</i> Genome
Published 2022-03-01“…Kinesins are essential motor molecules of the microtubule cytoskeleton. …”
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67
Investigating the role of Kinesin family in lung adenocarcinoma via integrated bioinformatics approach
Published 2023-06-01“…We conducted expression, stage plot and survival analyses on kinesin superfamily (KIF) and scrutinized the key prognostic kinesins. …”
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68
Physical limits on kinesin-5-mediated chromosome congression in the smallest mitotic spindles
Published 2015“…By contrast, kinesin-8 heterozygous mutant (KIP3/kip3∆) spindles exhibited the same spindle organization as wild type. …”
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Kinesin-7 CENP-E in tumorigenesis: Chromosome instability, spindle assembly checkpoint, and applications
Published 2024-03-01Subjects: “…kinesin…”
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71
Anchoring geometry is a significant factor in determining the direction of kinesin-14 motility on microtubules
Published 2022-09-01“…Abstract Kinesin-14 microtubule-based motors have an N-terminal tail attaching the catalytic core to its load and usually move towards microtubule minus ends, whilst most other kinesins have a C-terminal tail and move towards plus ends. …”
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72
The architecture of kinesin-3 KLP-6 reveals a multilevel-lockdown mechanism for autoinhibition
Published 2022-07-01“…Autoinhibition ensures the proper spatiotemporal control of the kinesin-3 motor activity. Here, the authors present the full-length structure of kinesin-3 KLP-6 in an autoinhibited state and observe that all the internal domains entwine around the motor domain via a multilevel-lockdown mechanism.…”
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73
Kinesin-6 Klp9 orchestrates spindle elongation by regulating microtubule sliding and growth
Published 2021-06-01Subjects: Get full text
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74
Kinesin-5 Eg5 is essential for spindle assembly, chromosome stability and organogenesis in development
Published 2022-12-01“…Abstract Chromosome stability relies on bipolar spindle assembly and faithful chromosome segregation during cell division. Kinesin-5 Eg5 is a plus-end-directed kinesin motor protein, which is essential for spindle pole separation and chromosome alignment in mitosis. …”
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75
Chaperonin CCT controls extracellular vesicle production and cell metabolism through kinesin dynamics
Published 2023-06-01“…This process accelerates the biogenesis of multivesicular bodies leading to higher EV production through the dynamic regulation of microtubule‐based kinesin motors. These findings connect proteostasis with lipid metabolism through an unexpected role of CCT.…”
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76
Structural basis for isoform-specific kinesin-1 recognition of Y-acidic cargo adaptors
Published 2018-10-01Subjects: Get full text
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Functional characterisation and drug target validation of a mitotic kinesin-13 in Trypanosoma brucei.
Published 2010-08-01“…Mitotic kinesins are essential for faithful chromosome segregation and cell proliferation. …”
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79
Identifying Mitotic Kinesins as Potential Prognostic Biomarkers in Ovarian Cancer Using Bioinformatic Analyses
Published 2022-02-01Subjects: “…mitotic kinesins…”
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80
Yeast Kinesin-5 Motor Protein CIN8 Promotes Accurate Chromosome Segregation
Published 2022-07-01Subjects: “…kinesin-5 motor proteins…”
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