Structural basis of cooperativity in kinesin revealed by 3D reconstruction of a two-head-bound state on microtubules by Daifei Liu, Xueqi Liu, Zhiguo Shang, Charles V Sindelar

Subjects: “…Kinesin…”
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Connecting neurodevelopment to neurodegeneration: a spotlight on the role of kinesin superfamily protein 2A (KIF2A) by Nuria Ruiz-Reig, Janne Hakanen, Fadel Tissir

Subjects: “…brain disorders; cortical malformations; kinesin; microtubules; neurodegeneration; neurodevelopment…”
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Kinesin Superfamily Member 18B (KIF18B) Promotes Cell Proliferation in Colon Adenocarcinoma [Retraction] by Zhao F, Feng Y, Zhang X, Liu X, Li A

Subjects: “…kinesin superfamily proteins…”
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How Essential Kinesin-5 Becomes Non-Essential in Fission Yeast: Force Balance and Microtubule Dynamics Matter by Masashi Yukawa, Yasuhiro Teratani, Takashi Toda

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The Minus-End-Directed Kinesin OsDLK Shuttles to the Nucleus and Modulates the Expression of Cold-Box Factor 4 by Xiaolu Xu, Sabine Hummel, Klaus Harter, Üner Kolukisaoglu, Michael Riemann, Peter Nick

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Structural model of microtubule dynamics inhibition by kinesin-4 from the crystal structure of KLP-12 –tubulin complex by Shinya Taguchi, Juri Nakano, Tsuyoshi Imasaki, Tomoki Kita, Yumiko Saijo-Hamano, Naoki Sakai, Hideki Shigematsu, Hiromichi Okuma, Takahiro Shimizu, Eriko Nitta, Satoshi Kikkawa, Satoshi Mizobuchi, Shinsuke Niwa, Ryo Nitta

Subjects: “…kinesin-4…”
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Intracellular functions and motile properties of bi-directional kinesin-5 Cin8 are regulated by neck linker docking by Alina Goldstein-Levitin, Himanshu Pandey, Kanary Allhuzaeel, Itamar Kass, Larisa Gheber

Subjects: “…kinesin-5…”
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Neck linker docking is critical for Kinesin-1 force generation in cells but at a cost to motor speed and processivity by Breane G Budaitis, Shashank Jariwala, Dana N Reinemann, Kristin I Schimert, Guido Scarabelli, Barry J Grant, David Sept, Matthew J Lang, Kristen J Verhey

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The SPF27 homologue Num1 connects splicing and kinesin 1-dependent cytoplasmic trafficking in Ustilago maydis. by Nikola Kellner, Kai Heimel, Theresa Obhof, Florian Finkernagel, Jörg Kämper

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The kinesin-5 tail domain directly modulates the mechanochemical cycle of the motor domain for anti-parallel microtubule sliding by Tatyana Bodrug, Elizabeth M Wilson-Kubalek, Stanley Nithianantham, Alex F Thompson, April Alfieri, Ignas Gaska, Jennifer Major, Garrett Debs, Sayaka Inagaki, Pedro Gutierrez, Larisa Gheber, Richard J McKenney, Charles Vaughn Sindelar, Ronald Milligan, Jason Stumpff, Steven S Rosenfeld, Scott T Forth, Jawdat Al-Bassam

Subjects: “…kinesin-5…”
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Arabidopsis kinesins HINKEL and TETRASPORE act redundantly to control cell plate expansion during cytokinesis in the male gametophyte. by Oh, SA, Bourdon, V, Das 'Pal, M, Dickinson, H, Twell, D

“…Activation of the NACK-PQR MAP kinase signaling pathway, which is essential for somatic cell cytokinesis in tobacco, depends upon the NACK1 and NACK2 kinesin-related proteins. Their Arabidopsis orthologs, HINKEL (HIK) and TETRASPORE (TES), were reported to be essential for cytokinesis in somatic cells and in microsporocytes, respectively. …”

Transcriptome Analysis of Potential Regulatory Genes under Chemical Doubling in Maize Haploids by Youqiang Li, Penglin Zhan, Rumin Pu, Wenqi Xiang, Xin Meng, Shiqi Yang, Gaojiao Hu, Shuang Zhao, Jialong Han, Chao Xia, Hai Lan, Qingjun Wang, Jingwei Li, Yanli Lu, Yongtao Yu, Changjian Liao, Gaoke Li, Haijian Lin

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Editorial: Microtubule-associated molecular motors: Transport mechanisms and role in disease by Virupakshi Soppina, Xin Xiang, Senthil Arumugam

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Motor processivity and speed determine structure and dynamics of microtubule-motor assemblies by Rachel A Banks, Vahe Galstyan, Heun Jin Lee, Soichi Hirokawa, Athena Ierokomos, Tyler D Ross, Zev Bryant, Matt Thomson, Rob Phillips

Subjects: “…kinesin…”
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The ALS-Associated FUS (P525L) Variant Does Not Directly Interfere with Microtubule-Dependent Kinesin-1 Motility by Anne Seifert, Hauke Drechsler, Julia Japtok, Till Korten, Stefan Diez, Andreas Hermann

“…To test this hypothesis, we studied the effect of FUS on kinesin-1 motility in vitro. Using a modified microtubule gliding motility assay on surfaces coated with kinesin-1 motor proteins, we showed that neither recombinant wildtype and P525L FUS variants nor lysates from isogenic ALS-patient-specific iPSC-derived spinal motor neurons expressing those FUS variants significantly affected gliding velocities. …”
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Kinesin-6 regulates cell-size-dependent spindle elongation velocity to keep mitosis duration constant in fission yeast by Lara Katharina Krüger, Jérémie-Luc Sanchez, Anne Paoletti, Phong Thanh Tran

“…We further reveal how the velocity of spindle elongation is regulated: coupled to cell size, the amount of kinesin-6 Klp9 molecules increases, resulting in an acceleration of spindle elongation in anaphase B. …”
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Negative Modulation of the Angiogenic Cascade Induced by Allosteric Kinesin Eg5 Inhibitors in a Gastric Adenocarcinoma In Vitro Model by Alessia Ricci, Marialucia Gallorini, Donatella Del Bufalo, Amelia Cataldi, Ilaria D’Agostino, Simone Carradori, Susi Zara

Subjects: “…kinesins…”
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Reduction of kinesin I heavy chain decreases tau hyperphosphorylation, aggregation, and memory impairment in Alzheimer’s disease and tauopathy models by Karthikeyan Selvarasu, Abhay Kumar Singh, Ashok Iyaswamy, Sravan Gopalkrishnashetty Sreenivasmurthy, Senthilkumar Krishnamoorthi, Amal Kanti Bera, Jian-Dong Huang, Siva Sundara Kumar Durairajan

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The kinesin Kif21b binds myosin Va and mediates changes in actin dynamics underlying homeostatic synaptic downscaling by Kira V. Gromova, Edda Thies, Philipp C. Janiesch, Felix P. Lützenkirchen, Yipeng Zhu, Daniele Stajano, Céline D. Dürst, Michaela Schweizer, Anja Konietzny, Marina Mikhaylova, Christine E. Gee, Matthias Kneussel

“…Consistent with a role of the kinesin in regulating actin dynamics, Kif21b overexpression promotes actin polymerization. …”
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Design, synthesis and docking study of 3,4-dihydropyrimidine-2-one derivatives as inhibitors of the Mitotic Kinesin, Eg5 by Hossein Sadeghpour, Ramin Miri, Seyed Ahmad Ebadi, Shima Mohammadebrahimi, Elham Riazimontazer

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