Consumption of Diet Containing Free Amino Acids Exacerbates Colitis in Mice by Adna Luciana Souza, Adna Luciana Souza, Sarah Leão Fiorini Aguiar, Mariana Camila Gonçalves Miranda, Luisa Lemos, Mauro Andrade Freitas Guimaraes, Daniela Silva Reis, Patrícia Aparecida Vieira Barros, Emerson Soares Veloso, Toniana Gonçalves Carvalho, Fabiola Mara Ribeiro, Enio Ferreira, Denise Carmona Cara, Ana Cristina Gomes-Santos, Ana Cristina Gomes-Santos, Ana Maria Caetano Faria

“…We showed that consumption of a AA diet by adult mature mice lead to various immunological changes including decrease in the production of serum IgG as well as increase in the levels of IL-6, IL-17A, TGF-β, and IL-10 in the small and large intestines. It also led to changes in the intestinal morphology, to increase in intestinal permeability, in the number of total and activated CD4+ T cells in the small intestine as well as in the frequency of proliferating cells in the colon. …”
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Epithelial, metabolic and innate immunity transcriptomic signatures differentiating the rumen from other sheep and mammalian gastrointestinal tract tissues by Ruidong Xiang, Victor Hutton Oddy, Alan L. Archibald, Phillip E. Vercoe, Brian P. Dalrymple

“…The gene encoding a poorly characterized member of the maltase-glucoamylase family (MGAM2), predicted to play a role in the degradation of starch or glycogen, was highly expressed in the small and large intestines. Discussion. The rumen appears to be a specialised stratified cornified epithelium, probably derived from the oesophagus, which has gained some liver-like and other specialized metabolic functions, but probably not by expression of pre-existing colon metabolic programs. …”
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Epidemiological and pathological aspects of noninfectious diseases of the gastrointestinal tract in 114 horses in Southern Brazil by Matheus V. Bianchi, Paula R. Ribeiro, Alanna S. Stolf, Marianna Bertolini, Cláudio J.M. Laisse, Luciana Sonne, David Driemeier, Saulo P. Pavarini

“…Intestinal volvulus occurred within the small intestine (14 cases) and within the large intestines (13 cases). Grossly, there was intestinal ischemia with reddened to deep-black serosa and diffusely red mucosae. …”
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The effectiveness of a probiotic containing Bifidobacterium longum BB-46 and Enterococcus faecium ENCfa-68 in the treatment of post-infectious irritable bowel syndrome. Prospective... by Emiliya P. Yakovenko, Tatiana V. Strokova, Alexander N. Ivanov, Andrei V. Iakovenko, Irina Z. Gioeva, Malika A. Aldiyarova

“…A significant part of the patients had a combination of small and large intestinal dysbiosis. Histological examination of the colon mucosa showed signs of low degree of inflammation activity in all patients. …”
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Safety and efficacy of the tumor-selective adenovirus enadenotucirev, in combination with nivolumab, in patients with advanced/metastatic epithelial cancer: a phase I clinical tria... by Daruka Mahadevan, Tom Lillie, Wael Harb, Jordan Berlin, Mark Powell, Marwan Fakih, Lee Rosen, David Krige, Minesh Patel, Hani Babiker, Jo Carter, Chris Cox, Lola Parfitt

“…Overall, 31/51 (61%) patients experienced a grade 3–4 treatment-emergent adverse event (TEAE), most frequently anemia (12%), infusion-related reaction (8%), hyponatremia (6%), and large intestinal obstruction (6%). Seven (14%) patients experienced serious TEAEs related to enadenotucirev; the only serious TEAE related to enadenotucirev occurring in >1 patient was infusion-related reaction (n=2). …”
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Intestinal GPR119 activation by microbiota-derived metabolites impacts feeding behavior and energy metabolism by Miki Igarashi, Tetsuhiko Hayakawa, Haruka Tanabe, Keita Watanabe, Akari Nishida, Ikuo Kimura

“…Associated with this meal pattern, levels of oleoylethanolamide (OEA), an endogenous agonist of GPR119, in the luminal contents of the distal gastrointestinal tract were elevated within 2 h after refeeding. The large-intestinal infusion of OEA prolonged post-meal intervals and increased satiety in the first meal, but not the second meal. …”
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Neisseria gonorrhoeae Coinfection during Chlamydia muridarum Genital Latency Does Not Modulate Murine Vaginal Bacterial Shedding by Delia Onorini, Cory Ann Leonard, Regenia Phillips Campbell, Barbara Prähauser, Theresa Pesch, Robert V. Schoborg, Ann E. Jerse, Bernadetta Tarigan, Nicole Borel

“…C. muridarum inclusions were observed in large intestinal, but not genital, tissues during latency. …”
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Gastric mucormycosis by Sourav Bhowmik, Devendra Jadav, Divya Aggarwal, Raghvendra Singh Shekhawat

“…However, gastrointestinal (GI) mucormycosis cases have increased in the last two to three decades.2 Involvement of the GI tract in invasive mucormycosis is seen in 7–13% of cases.3 Out of which, involvement of the stomach is seen in 58% of the cases, and the remaining 42% involve small and large intestines. GI mucormycosis has been mostly associated with immunocompromised patients or premature infants.2 It has also been reported in immunocompetent patients.1 Many cases of GI mucormycosis are first recognized on autopsy, owing to its acute course and rapidly fatal nature.2 According to the literature, only about 25% of cases of GI mucormycosis are clinically diagnosed.4 The endoscopic appearance of gastric mucormycosis is usually a large ulcer with necrosis, eventually presenting an adherent, thick, green exudate.3 Figures 1A typically show green exudates surrounding the lesions. …”
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Fermentation of soybean residue (Okara) : potential in food applications by Mok, Wai Kit

“…Phenolic compounds and antioxidant activities were higher in fermented okara in both simulated small and large intestines. Production of SCFA was higher in the model using fermented okara. …”
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INHIBISI AKTIVITAS PROLIFERASI SEL DAN PERUBAHAN HISTOPATOLOGIS MUKOSA WISTAR DENGAN PEMBERIAN PERASAN SELEDRI by Aswiyanti Asri

“…<br />After the limit of this treatment was finished, all rats were terminated, and large intestines were resected. For the purpose of the histopathological evaluation one of cut sections processed by histological procedures regularlyand stained with H&amp;E. …”
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Magnetic resonance imaging of organ iron before and after correction of iron deficiency in patients with heart failure by Christoph Gertler, Nadja Jauert, Patrick Freyhardt, Miroslava Valentova, Sven Christopher Aland, Thula Cannon Walter‐Rittel, Christina Unterberg‐Buchwald, Marius Placzek, Virginia Ding‐Reinelt, Tarek Bekfani, Wolfram Doehner, Gerd Hasenfuß, Bernd Hamm, Anja Sandek

“…Methods and results We prospectively analysed 24 patients with systolic CHF for T2* MRI pattern of the left ventricle (LV), small and large intestines, spleen, liver, skeletal muscle, and brain for iron. …”
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Protective Effect of Bufei Jianpi Formula on Mucosal Barrier in a Rat Model with Chronic Obstructive Pulmonary Disease by Congcong ZHANG, Ya LI, Suyun LI, Jing MAO

“…Objective To explore the effects of Bufei Jianpi Formula on the expression levels of inflammatory factors in lung tissue, and the content of lung-gut related peptides in lung and colon tissues in a rat model of stable COPD based on a typical viscera theory of Traditional Chinese Medicine, namely &quot;the lungs and large intestines are interior-exteriorly related&quot; . …”
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