Improving the diagnostic yield of whole genome sequencing: neurodevelopmental and epilepsy disorders by Hashim, M

“…Moreover, the base resolution of WGS revealed complexities cryptic to karyotyping in 7 cases of the apparently balanced translocations. At least 30% of the apparently balanced translocations (ABTs) resulted in gene disruption that is likely to cause the phenotype, 15% disrupted topologically associated domains (TADs) for known disease genes, and 5% were associated with pathogenic genomic imbalances. …”

Structural and functional characterisation of the collagen binding domain of fibronectin by Millard, CJ

“…However, the presence of at least a single GlcNAc sugar residue on the second sugar chain site on 8Fn1 (N- linked to N511) is essential for full affinity binding to collagen. …”

Cognitive dynamic airspace management by Wong, Cheryl Sze Yin

“…Following that, the changing availability of airspace is tackled by the simultaneous optimisation of re-routing and resectorization. Last but not least, a deterministic multi-objective solver is developed to find optimal airspace sector shapes. …”
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Blood-stage malaria vaccine candidate RH5.1/Matrix-M in healthy Tanzanian adults and children; an open-label, non-randomised, first-in-human, single-centre, phase 1b trial by Silk, SE, Kalinga, WF, Salkeld, J, Mtaka, IM, Ahmed, S, Milando, F, Diouf, A, Bundi, CK, Balige, N, Hassan, O, Mkindi, CG, Rwezaula, S, Athumani, T, Mswata, S, Lilolime, NS, Simon, B, Msami, H, Mohamed, M, David, DM, Mohammed, L, Nyaulingo, G, Mwalimu, B, Juma, O, Mwamlima, TG, Sasamalo, IA, Mkumbange, RP, Kamage, JJ, Barrett, JR, King, LDW, Hou, MM, Pulido, D, Carnrot, C, Lawrie, AM, Cowan, RE, Nugent, FL, Roberts, R, Cho, J-S, Long, CA, Nielsen, CM, Miura, K, Draper, SJ, Olotu, AI, Minassian, AM

“…All participants receiving at least one dose of vaccine were included in the primary analyses. …”

Structured sparse representations for supervised and unsupervised learning by Zeng, Yijie

“…Convergence analysis is presented with theoretical justifications, and the computational complexity is among the lowest within the context of online CDL algorithms with least memory consumptions. Finally, this thesis proposes a novel masked version of SOCDL which can perform online learning on incomplete data for image inpainting.…”
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Evaluation of diabetic wound healing properties of moringa oleifera lam using in vitro and in vivo wound models by Muhammad Amali, Abubakar

“…Data were expressed as mean ± standard deviation, and results were selected from at least three independent experiments performed in triplicate. …”
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RES.14-002 Abdul Latif Jameel Poverty Action Lab Executive Training: Evaluating Social Programs 2011, Spring 2011 by Glennerster, Rachel, Banerjee, Abhijit, Duflo, Esther

“…To date, our evidence has helped improve the lives of at least 30 million people around the world through the scale-up of highly effective policies and programs. …”
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Global age-sex-specific mortality, life expectancy, and population estimates in 204 countries and territories and 811 subnational locations, 1950–2021, and the impact of the COVID-... by Schumacher, AE, Kyu, HH, Aali, A, Almidani, O, Bandyopadhyay, S, Basnyat, B, Maude, RJ, Bennett, D, Browne, AJ, Dolecek, C, Dunachie, SJ, Newton, CRJ, Rodriguez, JAB

“…Excess mortality rates exceeded 150 deaths per 100 000 population during at least one year of the pandemic in 80 countries and territories, whereas 20 nations had a negative excess mortality rate in 2020 or 2021, indicating that all-cause mortality in these countries was lower during the pandemic than expected based on historical trends. …”

Evolutionary explanations and the debunking of moral beliefs by Cofnas, N

“…It is argued here, based on work by Boehm (1999, 2012), that, from at least the time of the early Middle Paleolithic, human bands were controlled by powerful coalitions of the majority that deliberately guided the development of moral norms to promote the common good. …”

RES.14-001 Abdul Latif Jameel Poverty Action Lab Executive Training: Evaluating Social Programs 2009, Spring 2009 by Duflo, Esther, Glennerster, Rachel, Banerjee, Abhijit

“…To date, our evidence has helped improve the lives of at least 30 million people around the world through the scale-up of highly effective policies and programs. …”
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Electronic cigarettes for smoking cessation by Lindson, N, Butler, AR, McRobbie, H, Bullen, C, Hajek, P, Wu, AD, Begh, R, Theodoulou, A, Notley, C, Rigotti, NA, Turner, T, Livingstone-Banks, J, Morris, T, Hartmann-Boyce, J

“…Critical outcomes were abstinence from smoking after at least six months, adverse events (AEs), and serious adverse events (SAEs). …”

Electronic cigarettes for smoking cessation by Lindson, N, Butler, AR, McRobbie, H, Bullen, C, Hajek, P, Begh, R, Theodoulou, A, Notley, C, Rigotti, NA, Turner, T, Livingstone-Banks, J, Morris, T, Hartmann-Boyce, J

“…Critical outcomes were abstinence from smoking after at least six months, adverse events (AEs), and serious adverse events (SAEs). …”

Interventions for quitting vaping by Butler, AR, Lindson, N, Livingstone-Banks, J, Notley, C, Turner, T, Rigotti, NA, Fanshawe, TR, Dawkins, L, Begh, R, Wu, AD, Brose, L, Conde, M, Simonavičius, E, Hartmann-Boyce, J

“…Studies had to test an intervention designed to support people to quit vaping, and plan to measure at least one of our outcomes. <p><strong> Outcomes</strong></p> Critical outcomes: vaping cessation; change in combustible tobacco use at six months or longer; number of participants reporting serious adverse events (SAEs) at one week or longer. …”

Computational analysis for infectious diseases surveillance and host-pathogen interactions (in the context of Influenza A viruses) by Beyene, Biruhalem Taye

“…Then we integrated the differentially expressed genes (DEGs) in at least 3 viruses, with 1713 and 1780 host factors comprehensively curated from 11 siRNA and 13 interactome studies respectively. …”
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50 Years of quantum chromodynamics by Gross, Franz, Klempt, Eberhard, Brodsky, Stanley J., Buras, Andrzej J., Burkert, Volker D., Heinrich, Gudrun, Jakobs, Karl, Meyer, Curtis A., Orginos, Kostas, Strickland, Michael, Stachel, Johanna, Zanderighi, Giulia, Brambilla, Nora, Braun-Munzinger, Peter, Britzger, Daniel, Capstick, Simon, Cohen, Tom, Crede, Volker, Constantinou, Martha, Davies, Christine, Del Debbio, Luigi, Denig, Achim, DeTar, Carleton, Deur, Alexandre, Dokshitzer, Yuri, Dosch, Hans Günter, Dudek, Jozef, Dunford, Monica, Epelbaum, Evgeny, Escobedo, Miguel A., Fritzsch, Harald, Fukushima, Kenji, Gambino, Paolo, Gillberg, Dag, Gottlieb, Steven, Grafstrom, Per, Grazzini, Massimiliano, Grube, Boris, Guskov, Alexey, Iijima, Toru, Ji, Xiangdong, Karsch, Frithjof, Kluth, Stefan, Kogut, John B., Krauss, Frank, Kumano, Shunzo, Leinweber, Derek, Leutwyler, Heinrich, Li, Hai-Bo, Li, Yang, Malaescu, Bogdan, Mariotti, Chiara, Maris, Pieter, Marzani, Simone, Melnitchouk, Wally, Messchendorp, Johan, Meyer, Harvey, Mitchell, Ryan Edward, Mondal, Chandan, Nerling, Frank, Neubert, Sebastian, Pappagallo, Marco, Pastore, Saori, Peláez, José R., Puckett, Andrew, Qiu, Jianwei, Rabbertz, Klaus, Ramos, Alberto, Rossi, Patrizia, Rustamov, Anar, Schäfer, Andreas, Scherer, Stefan, Schindler, Matthias, Schramm, Steven, Shifman, Mikhail, Shuryak, Edward, Sjöstrand, Torbjörn, Sterman, George, Stewart, Iain W., Stroth, Joachim, Swanson, Eric, de Téramond, Guy F., Thoma, Ulrike, Vairo, Antonio, van Dyk, Danny, Vary, James, Virto, Javier, Vos, Marcel, Weiss, Christian, Wobisch, Markus, Wu, Sau Lan, Young, Christopher, Yuan, Feng, Zhao, Xingbo, Zhou, Xiaorong

“…QCD cannot be solved analytically, at least not yet, and the large value of $$\alpha _s$$ α s at low momentum transfers limits perturbative calculations to the high-energy region where $$Q^2\gg \varLambda _{{\textrm{QCD}}} ^2\simeq $$ Q 2 ≫ Λ QCD 2 ≃ (250 MeV) $$^2$$ 2 . …”
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Fabrication and characterization of Algan/Gan high electron mobility transistors on silicon by Tham, Wai Hoe

“…Therefore, we believe that the Au-free low temperature metal scheme has great prospects and potential in the fabrication of AlGaN/GaN HEMTs on Si platform. Last but not least, the performance of AlGaN/GaN HEMT is usually restricted by the severe gate leakage and high access resistance between the source and gate. …”
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Tsewang Norbu NGB by Cantwell, C, Mayer, R

“…</p> <p>2 We would be very grateful for any information or even clues which might give us any indication of the possible whereabouts of our missing volumes, or which might at least more clearly illuminate the historical facts. …”