An Emergent Discriminative Learning Is Elicited During Multifrequency Testing by Xingui Zhang, Xianhua Ye, Rui Cheng, Qi Li, Zhongju Xiao

“…In addition, the pure tone responses of mPFC neurons were inhibited after injection of lidocaine in the ipsilateral primary auditory cortex (A1), and the emergent discriminative learning was blocked by silencing both sides of A1 with muscimol. …”
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Filiform papilla of european and zebu cattle’s tongue by Cecília José Veríssimo, Selma Marques D’Agostino, Fernanda Ferreira Pessoa, Vânia Mirele Ferreira Carrijo, Ricardo Lopes Dias da Costa, Luciandra Macedo de Toledo

“…The animals were previously anaesthetized with 2% xylazine hydrochloride, and lidocaine hydrochloride 2.0 g. After the tissue removal, the local lesions received an ointment of triamcinolone acetonide, 1.0 mg/g. …”
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Comprehensive treatment of dogs with chronic generalized periodontitis in remission by N. M. Khomyn, A. R. Mysak, S. V. Tsisinska, V. V. Pritsak, N. V. Nazaruk, M. M. Khomyn

“…It was found that the dogs of the experimental group, after removal of tartar and rehabilitation of the oral cavity, were treated by using to the gums of ceftriaxone, diluted in 1% lidocaine hydrochloride solution in combination with 30 % dimexid solution 1 time per day for 7 days, anfluron injecteed intramuscularly at the rate of 1 ml 1 time per day for 7 days and caforsen – 0.1 ml/kg per day for 4 weeks. …”
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2-phenyl-1-(3-pyrrolidin-1-il-propyl)-1 H-indole hydrochloride (SS-68): Antiarrhythmic and cardioprotective activity and its molecular mechanisms of action (Part I) by Saida K. Bogus, Pavel A. Galenko-Yaroshevsky, Konstantin F. Suzdalev, Galina V. Sukoyan, Valery G. Abushkevich

“…It was found that with cardiogenic arrhythmias, SS-68 compound exhibits a pronounced antiarrhythmic effect and brings to normal the electrophysiological pattern of the heart, in most cases exceeding the analogous effect of reference drugs (amiodarone, lidocaine, aymaline, ethacizine, etmozine, quinidine anaprilin). …”
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Ultrasound-guided axillary vein puncture for cardiac devices implantation in patients under antithrombotic therapy by Mohammed ElJamili, Sok-Sithikun Bun, Decebal Gabriel Latcu, Tahar Delassi, Mustapha Elhattaoui, Nadir Saoudi

“…Guidewires insertion time (from lidocaïne administration), and complications were systematically studied. …”
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Quantitative Analysis of the Membrane Affinity of Local Anesthetics Using a Model Cell Membrane by Wanjae Choi, Hyunil Ryu, Ahmed Fuwad, Seulmini Goh, Chaoge Zhou, Jiwook Shim, Masahiro Takagi, Soonjo Kwon, Sun Min Kim, Tae-Joon Jeon

“…To analyze the effects of LAs on the cell membrane and compare the results with those from model membranes, morphological analysis and 50% inhibitory concentration (IC50) measurement of CCD-1064sk (fibroblast, human skin) membranes were carried out for lidocaine (LDC) and tetracaine (TTC), the most popular LAs in clinical use. …”
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In situ enrichment and determination of 6 kinds of caine-type anesthetics in cosmetics and rat serum by thin layer chromatography-Raman spectroscopy by Chao-Yang Zhao, Xinyue Ma, Jialin Zang, Tingting Liu, Huiyu Wang, Shuang Fu, Cuiyan Han, Huimin Sui

“…The target caine-type anesthetics, procaine hydrochloride (Pro), tetracaine hydrochloride (Tet), dibucaine (Dib), mepivacaine hydrochloride (Mep), lidocaine hydrochloride (Lid) and ropivacaine hydrochloride (Rop), were separated by TLC. …”
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Hypoxia inducible factor-1α mediates the mechanism of the Hedgehog pathway in tendinopathy repair by Asperosaponin VI by Kun Wang, Liang Cheng, Benxiang He, Yajun Tan

“…The tendinopathy model group was further divided into the model group (MG), ASA VI group (AG), and triamcinolone acetonide + lidocaine group (TG). Results: Compared with those in the MG group, IL-1 mRNA was significantly downregulated and IL-4 and IL-10 were increased in the AG group (P < 0.01). …”
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The Effect of Ultrasound-Guided Treatment of Symptomatic Partial Rotator Cuff Injury Under the Background of Deep Learning by Ping Xia, Feng Qin Zhu, Yan Fang, Shu Han Zhang, Zhi Feng Zhang, Xiaoming Li, Tao Chen

“…Mixed injection of 1 mL betamethasone and 5 mL lidocaine, following 5 mL PRP injected in 7-day intervals, were infiltrated directly into the lesion of supraspinatus interstitial RCT under ultrasound control. …”
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Efficacy and Safety of Dexmedetomidine Premedication in Balanced Anesthesia: A Systematic Review and Meta-Analysis in Dogs by Shi-Yue Pan, Gang Liu, Jia-Hao Lin, Yi-Peng Jin

“…Dexmedetomidine administration probably improved in sedation and analgesia in comparison to acepromazine, ketamine and lidocaine (MD: 1.96, 95% CI: [−0.08, 4.00], <i>p</i> = 0.06; MD: −0.95, 95% CI: [−1.52, −0.37] <i>p</i> = 0.001; respectively). …”
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<i>N</i>-Acetylcysteine Added to Local Anesthesia Reduces Scar Area and Width in Early Wound Healing—An Animal Model Study by Wiktor Paskal, Adriana M. Paskal, Piotr Pietruski, Albert Stachura, Kacper Pełka, Alan E. Woessner, Kyle P. Quinn, Michał Kopka, Ryszard Galus, Jarosław Wejman, Paweł Włodarski

“…Before the incisions were made, skin was injected either with lidocaine and epinephrine (one side) or with these agents supplemented with 0.015%, 0.03%, or 0.045% NAC (contralaterally). …”
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Anaesthetic and Perioperative Management of 14 Male New Zealand White Rabbits for Calvarial Bone Surgery by Mathieu Raillard, Carlotta Detotto, Sandro Grepper, Olgica Beslac, Masako Fujioka-Kobayashi, Benoit Schaller, Nikola Saulacic

“…Monitoring was clinical and instrumental (pulse-oximetry, capnography, invasive blood pressure, temperature, arterial blood gas analysis). Lidocaine was infiltrated at the surgical site and meloxicam was injected subcutaneously as perioperative analgesia. …”
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Efficacy of Hormonal and Nonhormonal Approaches to Vaginal Atrophy and Sexual Dysfunctions in Postmenopausal Women: A Systematic Review by Ayane Cristine Alves Sarmento, Ana Paula Ferreira Costa, Juliana Lírio, José Eleutério Jr, Pedro Vieira Baptista, Ana Katherine Gonçalves

“…The approaches tested to treat sexual dysfunction were as follows: lubricants and moisturizers (18 studies); phytoestrogens (14 studies); dehydroepiandrosterone (DHEA; 8 studies); ospemifene (5 studies); vaginal testosterone (4 studies); pelvic floor muscle exercises (2 studies); oxytocin (2 studies); vaginal CO2 laser (2 studies); lidocaine (1 study); and vitamin E vaginal suppository (1 study). …”
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Cutaneous targets for topical pain medications in patients with neuropathic pain: individual differential expression of biomarkers supports the need for personalized medicine by Phillip J. Albrecht, Yi Liu, George Houk, Beth Ruggiero, Daniel Banov, Marilyn Dockum, A.J. Day, Frank L. Rice, Gus Bassani

“…Referencing 5 of the most common actives used in topical pain relief formulations (ketamine, gabapentin, clonidine, baclofen, and lidocaine), and 3 well-established cutaneous mediators (ie, neuropeptides, cannabinoids, and vanilloids), comprehensive immunolabeling was used to quantify receptor biomarkers in skin biopsy samples taken from ipsilateral (pain) and contralateral (nonpain) dermatomes of patients with PHN. …”
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Analgesic effects of ultrasound-guided fourquadrant transversus abdominis plane in patients with cytoreductive surgery with hyperthermic intraperitoneal chemotherapy: a prospective... by Jaegyok Song, Nayoung Choi, Minji Kang, Sung Mi Ji, Dong-wook Kim, Min A Kwon

“…The patients received 4Q-TAP blocks in a 10 ml mixture of 2% lidocaine and 0.75% ropivacaine per site (4Q-TAP group, n = 36) or normal saline (control group, n = 33). …”
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Physiology of pregnancy and oral local anesthesia considerations by Xueer Zhou, Yunyu Zhong, Zijian Pan, Jiankang Zhang, Jian Pan

“…Results Standard oral local anesthesia is safe throughout the pregnancy. At present, 2% lidocaine with 1:200,000 epinephrine is considered to be the anesthetic agent that best balances safety and efficacy for pregnant women. …”
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Analysis of umbilical cord tissue as an indicator of in utero exposure to toxic adulterating substances by Kari M. Midthun, Brandon N. Nelson, Frederick G. Strathmann, Thom Browne, Barry K. Logan, Barry K. Logan

“…Many of the adulterants used in the street drug supply do have legitimate medicinal/therapeutic uses, including several of the compounds most frequently detected in this study. Caffeine and lidocaine were the most frequently identified compounds both individually (&gt;70% each) and in combination with each other. …”
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Comparative Effectiveness of Botulinum Toxin Injection for Chronic Shoulder Pain: A Meta-Analysis of Randomized Controlled Trials by Po-Cheng Hsu, Wei-Ting Wu, Der-Sheng Han, Ke-Vin Chang

“…Likewise, in terms of shoulder myofascial pain, the effectiveness of BoNT injections did not differ from the reference treatment (SMD: −0.212, 95% CI: −0.551 to 0.127 versus saline; SMD: 0.665, 95% CI: −0.260 to 1.590 versus dry needling and SMD: 1.093; 95% CI: 0.128 to 2.058 versus lidocaine) at one month post- intervention, and appeared superior (SMD: −0.314, 95% CI: −0.516 to −0.111 versus saline) between one and three months. …”
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Surgicel® fibrillar as an innovative analgesic reservoir for post-laparoscopic cholecystectomy pain management: Randomized double-blind trial by Esam Hamed, Ragaa Herdan, Ahmed M. Taha, Abdullah AlHaddad, Mohamed F. Mostafa

“…We hypothesized that Surgicel® could function as an innovative carrier for sustained-release postoperative analgesia.Methods Ninety patients (18–65 years) scheduled for LC were randomized to receive a mixture of 20 ml bupivacaine 0.5%, 10 ml lidocaine 2%, epinephrine 5 µg/ml, and morphine 0.1 mg/kg instilled at hepatic fossa, trocar sites, and under the right copula of the diaphragm (Group-I). …”
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The Modification and Performance of a Large Animal Anesthesia Machine (Tafonius®) in Order to Deliver Xenon to a Horse by Bruna Santangelo, Astrid Robin, Keith Simpson, Julie Potier, Michel Guichardant, Karine Portier, Karine Portier

“…Anesthesia was maintained with xenon and oxygen, co-administered with lidocaine. Ventilation was controlled. Cardiorespiratory variables, expired fraction of xenon (FeXe), blood gases were measured and xenon was detected in plasma. …”
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