Digital smartphone intervention to recognise and manage early warning signs in schizophrenia to prevent relapse: the EMPOWER feasibility cluster RCT by Andrew I Gumley, Simon Bradstreet, John Ainsworth, Stephanie Allan, Mario Alvarez-Jimenez, Maximillian Birchwood, Andrew Briggs, Sandra Bucci, Sue Cotton, Lidia Engel, Paul French, Reeva Lederman, Shôn Lewis, Matthew Machin, Graeme MacLennan, Hamish McLeod, Nicola McMeekin, Cathy Mihalopoulos, Emma Morton, John Norrie, Frank Reilly, Matthias Schwannauer, Swaran P Singh, Suresh Sundram, Andrew Thompson, Chris Williams, Alison Yung, Lorna Aucott, John Farhall, John Gleeson

“…This incremental cost-effectiveness ratio would be considered cost-effective when using the National Institute for Health and Care Excellence threshold of £20,000 per quality-adjusted life-year gained. Limitations: This was a feasibility study and the outcomes detected cannot be taken as evidence of efficacy or effectiveness. …”
Get full text

Does metformin reduce excess birthweight in offspring of obese pregnant women? A randomised controlled trial of efficacy, exploration of mechanisms and evaluation of other pregnanc... by Carolyn A Chiswick, Rebecca M Reynolds, Fiona C Denison, Amanda J Drake, Shareen Forbes, David E Newby, Brian R Walker, Siobhan Quenby, Susan Wray, Andrew Weeks, Hany Lashen, Aryelly Rodriguez, Gordon D Murray, Sonia Whyte, Ruth Andrew, Natalie Homer, Scott Semple, Calum Gray, Marian C Aldhous, Karen Noble, Sarah Cunningham-Burley, Alice Keely, Jane E Norman

Get full text

MK-2206 Alleviates Renal Fibrosis by Suppressing the Akt/mTOR Signaling Pathway In Vivo and In Vitro by Meiling Chen, Yihang Yu, Tao Mi, Qitong Guo, Bin Xiang, Xiaomao Tian, Liming Jin, Chunlan Long, Lianju Shen, Xing Liu, Jianbo Pan, Yuanyuan Zhang, Tao Xu, Deying Zhang, Guanghui Wei

Get full text

First observation of the decay of the 13/2+ isomer in 183Hg and B(M2) systematics of neutron transitions across the nuclear chart by H. Huang, W.Q. Zhang, A.N. Andreyev, Z. Liu, D. Seweryniak, Z.H. Li, C.Y. Guo, A.E. Barzakh, P. Van Duppen, B. Andel, S. Antalic, M. Block, A. Bronis, M.P. Carpenter, P. Copp, J.G. Cubiss, B. Ding, D.T. Doherty, Z. Favier, F. Giacoppo, T.H. Huang, B. Kindler, F.G. Kondev, T. Lauritsen, J.G. Li, G.S. Li, B. Lommel, H.Y. Lu, M. Al Monthery, P. Mošať, Y.F. Niu, C. Raison, W. Reviol, G. Savard, S. Stolze, G.L. Wilson, H.Y. Wu, Z.H. Wang, F.R. Xu, Q.B. Zeng, X.H. Yu, F.F. Zeng, X.H. Zhou

“…Using α−γ delayed coincidence measurements, the half-life of this isomer was measured to be 290(30) μs. …”
Get full text

Comparison research of vocabulary implicate of "Sabu" and "Sabuh" in Arabic and Persian poetry by Ali Akbar Mollaie

“…This type of dish has been adapted to the nomadic life style of the Arabs, and also reminds us  the tradition of carrying the Saboo in Persian poetry. …”
Get full text

Chromatin regulators in the TBX1 network confer risk for conotruncal heart defects in 22q11.2DS by Yingjie Zhao, Yujue Wang, Lijie Shi, Donna M. McDonald-McGinn, T. Blaine Crowley, Daniel E. McGinn, Oanh T. Tran, Daniella Miller, Jhih-Rong Lin, Elaine Zackai, H. Richard Johnston, Eva W. C. Chow, Jacob A. S. Vorstman, Claudia Vingerhoets, Therese van Amelsvoort, Doron Gothelf, Ann Swillen, Jeroen Breckpot, Joris R. Vermeesch, Stephan Eliez, Maude Schneider, Marianne B. M. van den Bree, Michael J. Owen, Wendy R. Kates, Gabriela M. Repetto, Vandana Shashi, Kelly Schoch, Carrie E. Bearden, M. Cristina Digilio, Marta Unolt, Carolina Putotto, Bruno Marino, Maria Pontillo, Marco Armando, Stefano Vicari, Kathleen Angkustsiri, Linda Campbell, Tiffany Busa, Damian Heine-Suñer, Kieran C. Murphy, Declan Murphy, Sixto García-Miñaúr, Luis Fernández, International 22q11.2 Brain and Behavior Consortium (IBBC), Zhengdong D. Zhang, Elizabeth Goldmuntz, Raquel E. Gur, Beverly S. Emanuel, Deyou Zheng, Christian R. Marshall, Anne S. Bassett, Tao Wang, Bernice E. Morrow

Get full text

Intravascular Lithotripsy for the Treatment of Stent Underexpansion: The Multicenter IVL-DRAGON Registry by Wojciech Wańha, Mariusz Tomaniak, Piotr Wańczura, Jacek Bil, Rafał Januszek, Rafał Wolny, Maksymilian P. Opolski, Łukasz Kuźma, Adam Janas, Tomasz Figatowski, Paweł Gąsior, Marek Milewski, Magda Roleder-Dylewska, Łukasz Lewicki, Jan Kulczycki, Adrian Włodarczak, Brunon Tomasiewicz, Sylwia Iwańczyk, Jerzy Sacha, Łukasz Koltowski, Miłosz Dziarmaga, Miłosz Jaguszewski, Paweł Kralisz, Bartosz Olajossy, Grzegorz Sobieszek, Krzysztof Dyrbuś, Mariusz Łebek, Grzegorz Smolka, Krzysztof Reczuch, Robert J. Gil, Sławomir Dobrzycki, Piotr Kwiatkowski, Marcin Rogala, Mariusz Gąsior, Andrzej Ochała, Janusz Kochman, Adam Witkowski, Maciej Lesiak, Fabrizio D’Ascenzo, Stanisław Bartuś, Wojciech Wojakowski

“…Conclusions: In this real-life, largest-to-date analysis of IVL use to manage underexpanded stent, IVL proved to be an effective and safe method for facilitating stent expansion and increasing luminal gain.…”
Get full text

Effects of yeast culture and oxalic acid supplementation on in vitro nutrient disappearance, rumen fermentation, and bacterial community composition by Natnael D. Aschalew, Natnael D. Aschalew, Longyu Zhang, Ziyuan Wang, Yuanhong Xia, Guopei Yin, Jianan Dong, Yuguo Zhen, Yuguo Zhen, Xuefeng Zhang, Xuefeng Zhang, Tao Wang, Tao Wang, Zhe Sun, Zhe Sun, Zhe Sun, Guixin Qin, Guixin Qin

Get full text

Les textiles dans les tombes gauloises à dépôt de crémation en vase métallique : usages pratiques, mises en scène et perspectives anthropologiques (seconde moitié du vie s.-ve s. a... by Elsa Desplanques

“…Neither leaving visible nor hiding represent trivial choices: the available ancient sources underscore the close connection between seeing and not seeing, and between life and death. In ancient texts and iconography, death is often described as an opaque material or nebulous envelope. …”
Get full text

Where Morphological and Molecular Classifications Meet: The Role of p53 Immunohistochemistry in the Prognosis of Low-Risk Endometrial Carcinoma (GLAMOUR Study) by Andrea Puppo, Giulio Fraternali Orcioni, Valentino Clignon, Yuri Musizzano, Carla Angela Zavattero, Giulia Vocino Trucco, Giacomo Maria Benazzo, Giuseppe Vizzielli, Stefano Restaino, Laura Mariuzzi, Maria Orsaria, Renato Seracchioli, Diego Raimondo, Linda Bertoldo, Stefano Uccella, Anna Caliò, Giulia Vittori Antisari, Simone Garzon, Vito Andrea Capozzi, Roberto Berretta, Francesco Cosentino, Alfredo Ercoli, Antonio Ieni, Martina Arcieri, Marcello Ceccaroni, Anna Pesci, Giulia Mantovani, Francesco Bruni, Giovanni Roviglione, Pio Zeppa, Antonio Raffone, Marco Camanni, Elena Maria Delpiano, Claudia Provenza, Martina Borghese, Giuseppe Migliaretti

Get full text

C9orf72 poly(PR) aggregation in nucleus induces ALS/FTD-related neurodegeneration in cynomolgus monkeys by Lizhu Xu, Dan Wang, Lu Zhao, Zhengsheng Yang, Xu Liu, Xinyue Li, Tingli Yuan, Ye Wang, Tianzhuang Huang, Ning Bian, Yuqun He, Xinglong Chen, Baohong Tian, Zexian Liu, Fucheng Luo, Wei Si, Guangping Gao, Weizhi Ji, Yuyu Niu, Jingkuan Wei

Get full text

Levamisole Suppresses CD4+ T-Cell Proliferation and Antigen-Presenting Cell Activation in Aplastic Anemia by Regulating the JAK/STAT and TLR Signaling Pathways by Jiali Wang, Jiali Wang, Jia Liu, Jia Liu, Mingyang Wang, Mingyang Wang, Fei Zhao, Fei Zhao, Meili Ge, Meili Ge, Li Liu, Li Liu, Erlie Jiang, Erlie Jiang, Sizhou Feng, Sizhou Feng, Mingzhe Han, Mingzhe Han, Xiaolei Pei, Xiaolei Pei, Yizhou Zheng, Yizhou Zheng

“…Aplastic anemia (AA) is a life-threatening disease primarily caused by a metabolic disorder and an altered immune response in the bone marrow (BM) microenvironment, where cytotoxic immune cells attack resident cells and lead to hematopoietic failure. …”
Get full text

PPM1K-regulated impaired catabolism of branched-chain amino acids orchestrates polycystic ovary syndromeResearch in context by Liangshan Mu, Zhenhong Ye, Junhao Hu, Yurong Zhang, Kai Chen, Haipeng Sun, Rong Li, Weian Mao, Xiaoyu Long, Chunmei Zhang, Yuchen Lai, Jun Liu, Yue Zhao, Jie Qiao

Get full text

Conceptualization and Validation of Components and Characteristics of Spiritual Leadership in Northeastern Universities of Iran by Mahdi Taghvaee, Alieza khorakian, Fariborz Rahimnia, Saeed Mortazavi

“…A spiritual leader tends to pursue a broader goal of life, meaning of the work, transcendence, belief, and feeling of the society. …”
Get full text

Clinical Characteristics of Patients with Ossification of the Posterior Longitudinal Ligament and a High OP Index: A Multicenter Cross-Sectional Study (JOSL Study) by Takashi Hirai, Toshitaka Yoshii, Jun Hashimoto, Shuta Ushio, Kanji Mori, Satoshi Maki, Keiichi Katsumi, Narihito Nagoshi, Kazuhiro Takeuchi, Takeo Furuya, Kei Watanabe, Norihiro Nishida, Soraya Nishimura, Kota Watanabe, Takashi Kaito, Satoshi Kato, Katsuya Nagashima, Masao Koda, Hiroaki Nakashima, Shiro Imagama, Kazuma Murata, Yuji Matsuoka, Kanichiro Wada, Atsushi Kimura, Tetsuro Ohba, Hiroyuki Katoh, Masahiko Watanabe, Yukihiro Matsuyama, Hiroshi Ozawa, Hirotaka Haro, Katsushi Takeshita, Morio Matsumoto, Masaya Nakamura, Satoru Egawa, Yu Matsukura, Hiroyuki Inose, Atsushi Okawa, Masashi Yamazaki, Yoshiharu Kawaguchi

“…Patients in the high OP index group also had significantly poorer scores for lower extremity function and quality of life on the JOA-CMEQ and in each domain but not for body pain on the JOA-BPEQ compared with those in the moderate/low OP index group. …”
Get full text

In Vitro and In Vivo Effect of Amikacin and Imipenem Combinations against Multidrug-Resistant <i>E. coli</i> by Sara Mahmoud Farhan, Rehab Mahmoud Abd El-Baky, Salah Abdalla, Ahmed Osama EL-Gendy, Hala Rady Ahmed, Doaa Safwat Mohamed, Amr El Zawily, Ahmed Farag Azmy

“…Introduction: The emergence of multidrug-resistant (MDR) <i>E. coli</i> has developed worldwide; therefore, the use of antibiotic combinations may be an effective strategy to target resistant bacteria and fight life-threatening infections. The current study was performed to evaluate the in vitro and in vivo efficacy of amikacin and imipenem alone and in combination against multidrug-resistant <i>E. coli.…”
Get full text

Clinical Approach in the Management of Paediatric Patients with Familial Hypercholesterolemia: A National Survey Conducted by the LIPIGEN Paediatric Group by Cristina Pederiva, Marta Gazzotti, Marcello Arca, Maurizio Averna, Giuseppe Banderali, Giacomo Biasucci, Marta Brambilla, Paola Sabrina Buonuomo, Paolo Calabrò, Francesco Cipollone, Nadia Citroni, Sergio D’Addato, Maria Del Ben, Simonetta Genovesi, Ornella Guardamagna, Gabriella Iannuzzo, Lorenzo Iughetti, Giuseppe Mandraffino, Lorenzo Maroni, Giuliana Mombelli, Sandro Muntoni, Fabio Nascimbeni, Angelina Passaro, Fabio Pellegatta, Matteo Pirro, Livia Pisciotta, Roberta Pujia, Riccardo Sarzani, Roberto Scicali, Patrizia Suppressa, Sabina Zambon, Maria Grazia Zenti, Sebastiano Calandra, Alberico Luigi Catapano, Patrizia Tarugi, Federica Galimberti, Manuela Casula, Maria Elena Capra

Get full text

Charakterystyka postawy ciała dzieci w wieku przedszkolnym regionu bydgoskiego = Characteristics of body posture of Bydgoszcz region pre-school children by Monika Katarzyna Mieszkowska, Magdalena Kochanowicz, Michał Garbin, Grzegorz Srokowski, Maja Tomczyk, Elżbieta Piskorska

“…Early diagnosis and its correction allow achieving measurable effects influencing on the quality of life in adulthood. The aim of the study was to assess the selected posture parameters of preschool children. …”
Get full text

Testing for pharmacogenomic predictors of ppRNFL thinning in individuals exposed to vigabatrin by Isabelle Boothman, Isabelle Boothman, Isabelle Boothman, Lisa M. Clayton, Lisa M. Clayton, Mark McCormack, Alexandra McKibben Driscoll, Remi Stevelink, Patrick Moloney, Roland Krause, Wolfram S. Kunz, Sarah Diehl, Terence J. O’Brien, Graeme J. Sills, Gerrit-Jan de Haan, Federico Zara, Federico Zara, Bobby P. Koeleman, Chantal Depondt, Anthony G. Marson, Hreinn Stefansson, Kari Stefansson, John Craig, Michael R. Johnson, Pasquale Striano, Pasquale Striano, Holger Lerche, Simon J. Furney, Norman Delanty, Consortium EpiPGX, Sanjay M. Sisodiya, Sanjay M. Sisodiya, Gianpiero L. Cavalleri, Gianpiero L. Cavalleri, Gianpiero L. Cavalleri, Joseph Willis, Mojgansadat Borghei, Simona Donatello, Martin J. Brodie, Pauls Auce, Andrea Jorgensen, Sarah R. Langley, Yvonne Weber, Christian Hengsbach, Martin Krenn, Fritz Zimprich, Ekaterina Pataraia, Karl Martin Klein, Hiltrud Muhle, Rikke S. Møller, Marina Nikanorova, Stefan Wolking, Ellen Campbell, Antonella Riva, Marcello Scala

Get full text

Analysis of the Authentic Leadership Identity Indicators for Human Resource Improvement Using the Interpretative Ranking Process Approach (IRP) by Reza Sepahvand, Mohsen Arefnezhad, Ali Shariyatnezhad

“…It is impossible to achieve the goals of development, construction, and establishing a proper condition for a supreme organizational life, unless there is a growth, enhancement, and improvement of human resources in all areas of the organization. …”
Get full text