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381521
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381522
Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond
Published 2017“…The combined biochemical and cellular assays presented here suggest mechanisms of action for 135 (34%) of the compounds active in killing multiple life-cycle stages of the malaria parasite, including asexual blood, liver, gametocyte, gametes and insect ookinete stages. …”
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Article -
381523
A TALEN Genome-Editing System for Generating Human Stem Cell-Based Disease Models
Published 2017“…Another limitation is that many gene mutations that would be informative for disease biology if they could be studied in isolated cells are incompatible with human life (i.e., embryonic lethal). Classical gene-targeting technology via homologous recombination has proven to be an invaluable tool of experimental biology through its use in mouse embryonic stem cells for generating germline knockout and knockin mice; however, its use in mammalian systems has been limited primarily to studies in mice. …”
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Article -
381524
24.01 Classics in Western Philosophy, Spring 2006
Published 2023“…You will get to grips with questions that have been significant to philosophy from its beginnings: questions about the nature of the mind or soul, the existence of God, the foundations of knowledge, ethics and the good life. In the process of evaluating the arguments of these philosophers, you will develop your own philosophical and analytical skills. …”
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381525
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381526
Bioinorganic Chemistry of the Human Host-Defense Protein Calprotectin
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Thesis -
381527
Phase separation in active matter : from schematic to realistic models
Published 2020“…This is a research activity carried out in collaboration with SCELSE, the Singapore Centre for Environmental Life Sciences Engineering. The goal has been that of ratio- nalizing all of the relevant processes influencing the early-stage biofilm formation, to develop a particle-resolved numerical model with that would help investigate the underlying physics. …”
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Thesis-Doctor of Philosophy -
381528
High power gallium nitride light-emitting diodes for efficient solid state lighting and displays
Published 2014“…Nitride based light-emitting diodes (LEDs) are considered to be the next generation lighting source, owing to their superior advantages including high brightness, high energy conversion efficiency, long life span, compact size, fast response, and low maintenance cost. …”
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Thesis -
381529
新加坡3-5岁华族双语前儿童用汉语对“拉”的手部动作的描述分析 = Three-to-five-year-old bilingual Singapore children’s description of the hand action “La” in Chinese...
Published 2015“…Also, the acquired verbs are verbs seen and experienced in a child’s life. Singapore is a multi-ethnic and multi-lingual country. …”
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Final Year Project (FYP) -
381530
Learning spike time codes through supervised and unsupervised structural plasticity
Published 2016“…We have also presented results of applying this rule to real life spike classification problems from the field of tactile sensing. …”
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Thesis -
381531
A study of big data computing platforms : performance, fairness and energy consumption
Published 2017“…Although the elderly has wisdom and wealth gathered from their life experience, they often require long-term assistance from others. …”
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Thesis -
381532
Scalable analysis for malware and vulnerability detection in binaries
Published 2018“…Experimental results on ten real-life projects have demonstrated that Leopard can cover 66% of vulnerabilities by identifying 20% of functions as vulnerable.…”
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Thesis -
381533
Interventions for reducing red blood cell transfusion in adults undergoing hip fracture surgery: an overview of systematic reviews
Published 2023“…Outcomes were: number of people requiring ABT, volume of transfused blood (measured as units of packed red blood cells (PRC)), postoperative delirium, adverse events, activities of daily living (ADL), health‐related quality of life (HRQoL), and mortality.</p> <p><strong>Main results:</strong> We found 26 systematic reviews including 36 RCTs (3923 participants), which only evaluated tranexamic acid and iron. …”
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381534
Inter-union membership disputes and their resolution by the Disputes Committee of the Trades Union Congress
Published 1976“…The immediate causes of inter-union disputes concern us here; that is to say, those aspects of industrial life which in fact provoke conflict between unions. …”
Thesis -
381535
Circadian influence on intrusive re-experiencing in trauma survivors’ daily lives
Published 2022“…</p> <p><strong>Methods:</strong> Fifty trauma survivors reported intrusive memories for 7 consecutive days using ecological momentary assessment in their daily life. We investigated (i) time-of-day dependent effects on frequency and distribution of intrusive re-experiencing in the overall sample as well as in PTSD versus non-PTSD and (ii) time-of-day dependent effects on the memory characteristics intrusiveness, vividness, nowness and fear.…”
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381536
Hegel's Æsthetics and the end of art
Published 1999“…The implication, of course, is that when, in Hegel's words, '<em>a shape of life has grown old</em>', as he believes art has, all we can do as philosophers is try to understand what has happened and why . …”
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381537
Surgical interventions for treating extracapsular hip fractures in older adults: a network meta‐analysis
Published 2022“…We collected data for three outcomes at different time points: mortality and health‐related quality of life (HRQoL) ‐ both reported within 4 months, at 12 months and after 24 months of surgery, and unplanned return to theatre (at end of study follow‐up). …”
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381538
Biologics for chronic rhinosinusitis
Published 2021“…Our primary outcomes were disease‐specific health‐related quality of life (HRQL), disease severity and serious adverse events (SAEs). …”
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381539
The transformation of the medieval sermon
Published 1977“…</p> <p>The decisive change was the revival of preaching to the laity, which had ceased to play a major part in religious life between the fall of the Roman empire and the rise of the medieval towns. …”
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381540
Studies in the chemistry of flavins and flavoproteins
Published 1969“…On plotting the logarithm of intensity or of the reciprocal of half-life (decay is exponential) against the reciprocal of temperature biphasic Arrhenius plots are obtained. …”
Thesis