EGF and IGF1 affect sunitinib activity in BP-NEN: new putative targets beyond VEGFR? by Giulia Bresciani, Angeliki Ditsiou, Chiara Cilibrasi, Viviana Vella, Federico Rea, Marco Schiavon, Narciso Giorgio Cavallesco, Georgios Giamas, Maria Chiara Zatelli, Teresa Gagliano

Subjects: Get full text

Type 1 Insulin-Like Growth Factor Receptor Nuclear Localization in High-Grade Glioma Cells Enhances Motility, Metabolism, and In Vivo Tumorigenesis by Ayelen Martin, María Celia Fernandez, Elizabeth R. Cattaneo, Claudio D. Schuster, Marcela Venara, Florencia Clément, Ariel Berenstein, Ariel Berenstein, Mercedes García Lombardi, Ignacio Bergadá, Mariana Gutierrez, Marcelo A. Martí, María R. Gonzalez-Baro, Patricia A. Pennisi

Subjects: Get full text

Linsitinib, an IGF-1R inhibitor, attenuates disease development and progression in a model of thyroid eye disease by Anne Gulbins, Mareike Horstmann, Anke Daser, Ulrich Flögel, Michael Oeverhaus, Nikolaos E. Bechrakis, J. Paul Banga, Simone Keitsch, Barbara Wilker, Gerd Krause, Gary D. Hammer, Andrew G. Spencer, Ryan Zeidan, Anja Eckstein, Svenja Philipp, Gina-Eva Görtz

Subjects: Get full text

Effects of linsitinib on M22 and IGF:1-treated 3D spheroids of human orbital fibroblasts by Fumihito Hikage, Megumi Suzuki, Tatsuya Sato, Araya Umetsu, Toshifumi Ogawa, Nami Nishikiori, Masato Furuhashi, Hiroshi Ohguro, Megumi Watanabe

Subjects: Get full text

Linsitinib inhibits proliferation and induces apoptosis of both IGF-1R and TSH-R expressing cells by Maximilian Luffy, Anna-Lena Ganz, Stefanie Wagner, Jan Wolf, Julian Ropertz, Ryan Zeidan, Jeffrey D. Kent, Raymond S. Douglas, George J. Kahaly

Subjects: “…Linsitinib…”
Get full text

Potential involvement of the bone marrow in experimental Graves’ disease and thyroid eye disease by Anne Gulbins, Mareike Horstmann, Simone Keitsch, Matthias Soddemann, Barbara Wilker, Gregory C. Wilson, Ryan Zeidan, Gary D. Hammer, Anke Daser, Nikolaos E. Bechrakis, Gina-Eva Görtz, Anja Eckstein

Subjects: Get full text