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Biotechnology applications of tethered lipid bilayer membranes
Published 2014“…The importance of cell membranes in biological systems has prompted the development of model membrane platforms that recapitulate fundamental aspects of membrane biology, especially the lipid bilayer environment. Tethered lipid bilayers represent one of the most promising classes of model membranes and are based on the immobilization of a planar lipid bilayer on a solid support that enables characterization by a wide range of surface-sensitive analytical techniques. …”
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Bicelle-based supported lipid bilayer platforms
Published 2022“…The deposition of bicelles, which are two-dimensional lipid nanostructures composed of long- and short-chain phospholipids, onto hydrophilic surfaces is an emerging technique to fabricate supported lipid bilayers (SLBs). While successful SLB fabrication has been demonstrated and some mechanistic understanding of bicelle-mediated SLB formation gained, numerous other aspects remain to be understood. …”
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Thesis-Doctor of Philosophy -
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Integrating carbon nanotubes and lipid bilayer for biosensing
Published 2011“…Here, we have developed a novel system by integrating artificial lipid bilayer (biomimetic membrane) with single-walled carbon nanotube networks (SWNT-net) based field-effect transistor (FET), and demonstrated that such hybrid nanoelectronic biosensors can specifically and electronically detect the presence and dynamic activities of ionophores (specifically, gramicidin and calcimycin) in their native lipid environment. …”
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Nanoscale measurements of the mechanical properties of lipid bilayers
Published 2014“…<p>Lipid bilayers form the basis of the membranes that serve as a barrier between a cell and its physiological environment. …”
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The molecolar interaction of pneumolysin with lipid bilayers and cholesterol
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Raman spectra of planar supported lipid bilayers.
Published 2005“…Raman scattering has been used to obtain high quality vibrational spectra of planar supported lipid bilayers (pslb's) at the silica/water interface without the use of resonance or surface enhancement. …”
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The computer simulation of lipid bilayers and biological membranes
Published 1996“…<p>Computer simulations of lipid bilayers and biological membranes using molecular mechanics calculations have been undertaken in order to study these complex systems which are so vital in the control and functioning of many biological processes.…”
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DNA and lipid bilayers: self-assembly and insertion.
Published 2008“…To gain insight into the interactions of DNA with zwitterionic and cationic (dimyristoyltrimethylammonium propane (DMTAP)) lipids, we have used coarse-grained molecular dynamics simulations to study the self-assembly of DPPC and DPPC/DMTAP lipid bilayers in the presence of a DNA dodecamer. We observed the spontaneous formation of lipid bilayers from initial systems containing randomly placed lipids, water-counterions and DNA. …”
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Distribution and dynamics of adamantanes in a lipid bilayer.
Published 2008“…An understanding of how these compounds interact with the lipid bilayer is thus of great interest. We used molecular-dynamics simulations to calculate the potential of mean force of adamantanes in a lipid bilayer. …”
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Dataset on interactions of membrane active agents with lipid bilayers
Published 2020-04-01“…Complete interpretation of the data is found in the associated original article ‘charge-based interactions of antimicrobial peptides and general drugs with lipid bilayers’ [1]. Data on molecular dynamic simulations of the drug lipid complexes are provided. …”
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Functional regulation of aquaporin dynamics by lipid bilayer composition
Published 2024-02-01“…Abstract With the diversity of lipid-protein interactions, any observed membrane protein dynamics or functions directly depend on the lipid bilayer selection. However, the implications of lipid bilayer choice are seldom considered unless characteristic lipid-protein interactions have been previously reported. …”
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The Effect of Cholesterol in SOPC Lipid Bilayers at Low Temperatures
Published 2023-02-01“…We study the behavior of lipid bilayers composed of SOPC (1-stearoyl-2-oleoyl-sn-glycero-3-phosphocholine) with different concentrations of cholesterol, ranging from 10 mol% to 50 mol% at 273 K. …”
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Ibuprofen in a Lipid Bilayer: Nanoscale Spatial Arrangement
Published 2022-10-01Subjects: Get full text
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Domain Localization by Graphene Oxide in Supported Lipid Bilayers
Published 2023-04-01Subjects: “…lipid bilayer membrane…”
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Direct Observation of Cholesterol Dimers and Tetramers in Lipid Bilayers
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Article