Adaptation of Oxidative Phosphorylation Machinery Compensates for Hepatic Lipotoxicity in Early Stages of MAFLD by Pia Fahlbusch, Aleksandra Nikolic, Sonja Hartwig, Sylvia Jacob, Ulrike Kettel, Cornelia Köllmer, Hadi Al-Hasani, Stefan Lehr, Dirk Müller-Wieland, Birgit Knebel, Jörg Kotzka

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Comparison of the effects of monounsaturated fatty acids and polyunsaturated fatty acids on the lipotoxicity of islets by Wen Liu, Min Zhu, Jingyi Liu, Shan Su, Xin Zeng, Fudong Fu, Yanrong Lu, Zhiyong Rao, Younan Chen, Younan Chen

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Lipotoxic Injury Differentially Regulates Brain Microvascular Gene Expression in Male Mice by Saivageethi Nuthikattu, Dragan Milenkovic, John C. Rutledge, Amparo C. Villablanca

“…Much of the differentially expressed gene (DEG) was attributable to the differential regulation of cell signaling proteins and their transcription factors, approximately 4% was attributable to the differential expression of miRNAs, and 10% was due to other non-protein coding RNAs, primarily long non-coding RNAs (lncRNAs) and small nucleolar RNAs (snoRNAs) not previously described to be modified by the WD. Lipotoxic injury resulted in complex and multilevel molecular regulation of the hippocampal microvasculature involving transcriptional and post-transcriptional regulation and may provide a molecular basis for a better understanding of hyperlipidemia-associated dementia risk.…”
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Sphingosine-1 Phosphate Lyase Regulates Sensitivity of Pancreatic Beta-Cells to Lipotoxicity by Yadi Tang, Thomas Plötz, Markus H. Gräler, Ewa Gurgul-Convey

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Melatonin as a Repairing Agent in Cadmium- and Free Fatty Acid-Induced Lipotoxicity by Anna Migni, Francesca Mancuso, Tiziano Baroni, Gabriele Di Sante, Mario Rende, Francesco Galli, Desirée Bartolini

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Lipotoxicity and immunometabolism in ischemic acute kidney injury: current perspectives and future directions by Afolarin A. Otunla, Kumaran Shanmugarajah, Alun H. Davies, Joseph Shalhoub

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Activation of LXRs Reduces Oxysterol Lipotoxicity in RPE Cells by Promoting Mitochondrial Function by Lirong Xie, Qing Gu, Xingwei Wu, Lili Yin

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Regulation of autophagy by perilysosomal calcium: a new player in β-cell lipotoxicity by Ha Thu Nguyen, Andreas Wiederkehr, Claes B. Wollheim, Kyu-Sang Park

“…However, aberrant and persistent Ca2+ elevation upon lipotoxic stress increases mTOR activity and suppresses autophagy. …”
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Macrophage alternative activation confers protection against lipotoxicity-induced cell death by Lingling Dai, Prerna Bhargava, Kristopher J. Stanya, Ryan K. Alexander, Yae-Huei Liou, David Jacobi, Nelson H. Knudsen, Alexander Hyde, Matthew R. Gangl, Sihao Liu, Chih-Hao Lee

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CCN5 knockout mice exhibit lipotoxic cardiomyopathy with mild obesity and diabetes. by Jihwa Kim, Sanghyun Joo, Gwang Hyeon Eom, Seung Hoon Lee, Min-Ah Lee, Miyoung Lee, Ki Woo Kim, Do Han Kim, Hyun Kook, Tae Hwan Kwak, Woo Jin Park

“…Taken together, these results indicate that CCN5 KO leads to lipotoxic cardiomyopathy with mild obesity and diabetes in mice.…”
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Hepatic Choline Transport Is Inhibited During Fatty Acid–Induced Lipotoxicity and Obesity by Conor O’Dwyer, Rebecca Yaworski, Sakie Katsumura, Peyman Ghorbani, Kaelan Gobeil Odai, Julia R.C. Nunes, Nicholas D. LeBlond, Sabrin Sanjana, Tyler T.K. Smith, Shauna Han, Kaitlyn D. Margison, Tommy Alain, Masahiro Morita, Morgan D. Fullerton

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Sex-Dependent Molecular Mechanisms of Lipotoxic Injury in Brain Microvasculature: Implications for Dementia by Saivageethi Nuthikattu, Dragan Milenkovic, John C. Rutledge, Amparo C. Villablanca

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Adipocytokines modulate ionic currents – A key to lipotoxicity potentiated cardiac arrhythmia by Yung-Kuo Lin, Yi-Jen Chen

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Competing endogenous RNAs in human astrocytes: crosstalk and interacting networks in response to lipotoxicity by Natalia Gil-Jaramillo, Andrés Felipe Aristizábal-Pachón, María Alejandra Luque Aleman, Valentina González Gómez, Hans Deyvy Escobar Hurtado, Laura Camila Girón Pinto, Juan Sebastian Jaime Camacho, Alexis Felipe Rojas-Cruz, Yeimy González-Giraldo, Andrés Pinzón, Janneth González

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Lipotoxic Proximal Tubular Injury: A Primary Event in Diabetic Kidney Disease by Hua Wang, Shu Zhang, Jia Guo, Jia Guo

Subjects: “…lipotoxicity…”
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Notoginsenoside R1 Ameliorates Cardiac Lipotoxicity Through AMPK Signaling Pathway by Xue Tian, Xu Chen, Qianqian Jiang, Qianbin Sun, Tiantian Liu, Yiqin Hong, Yawen Zhang, Yanyan Jiang, Mingyan Shao, Ran Yang, Chun Li, Chun Li, Chun Li, Qiyan Wang, Qiyan Wang, Qiyan Wang, Yong Wang, Yong Wang, Yong Wang

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Central Ceramide-Induced Hypothalamic Lipotoxicity and ER Stress Regulate Energy Balance by Cristina Contreras, Ismael González-García, Noelia Martínez-Sánchez, Patricia Seoane-Collazo, Jordi Jacas, Donald A. Morgan, Dolors Serra, Rosalía Gallego, Francisco Gonzalez, Núria Casals, Rubén Nogueiras, Kamal Rahmouni, Carlos Diéguez, Miguel López

“…Here, we demonstrate that ceramides induce lipotoxicity and hypothalamic ER stress, leading to sympathetic inhibition, reduced brown adipose tissue (BAT) thermogenesis, and weight gain. …”
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Role of lipotoxicity in achieving glycemic control in patients with diabetes type 2 and obesity by А. S. Ametov, N. A. Chernikova, F. R. Abdulkadirova, R. A. Pokrovskaya, O. Y. Alferova

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Feeding Angptl4 −/− mice trans fat promotes foam cell formation in mesenter... by Oteng, Antwi-Boasiako, Bhattacharya, Asmita, Brodesser, Susanne, Qi, Ling, Tan, Nguan Soon, Kersten, Sander

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The Role of Gender Differences and Menopause in Obesity-Related Renal Disease, Renal Inflammation and Lipotoxicity by Aaron Afonso-Alí, Esteban Porrini, Silvia Teixido-Trujillo, José Antonio Pérez-Pérez, Sergio Luis-Lima, Nieves Guadalupe Acosta-González, Irene Sosa-Paz, Laura Díaz-Martín, Covadonga Rodríguez-González, Ana Elena Rodríguez-Rodríguez

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