Correction: Fenofibrate Improves Renal Lipotoxicity through Activation of AMPK-PGC-1α in Mice.

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PPAR gamma 2 prevents lipotoxicity by controlling adipose tissue expandability and peripheral lipid metabolism. by Medina-Gomez, G, Gray, S, Yetukuri, L, Shimomura, K, Virtue, S, Campbell, M, Curtis, R, Jimenez-Linan, M, Blount, M, Yeo, G, Lopez, M, Seppanen-Laakso, T, Ashcroft, F, Oresic, M, Vidal-Puig, A

“…In summary, the PPARg2 isoform prevents lipotoxicity by (a) promoting adipose tissue expansion, (b) increasing the lipid-buffering capacity of peripheral organs, and (c) facilitating the adaptive proliferative response of beta-cells to insulin resistance.…”

Hormone-sensitive lipase protects adipose triglyceride lipase-deficient mice from lethal lipotoxic cardiomyopathy by Mika Yamada, Jinya Suzuki, Satsuki Sato, Yasuo Zenimaru, Rie Saito, Tadashi Konoshita, Fredric B. Kraemer, Tamotsu Ishizuka

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Cyclic AMP-binding protein Epac1 acts as a metabolic sensor to promote cardiomyocyte lipotoxicity by Marion Laudette, Yannis Sainte-Marie, Grégoire Cousin, Dorian Bergonnier, Ismahane Belhabib, Stéphanie Brun, Karina Formoso, Loubna Laib, Florence Tortosa, Camille Bergoglio, Bertrand Marcheix, Jan Borén, Olivier Lairez, Jérémy Fauconnier, Alexandre Lucas, Jeanne Mialet-Perez, Cédric Moro, Frank Lezoualc’h

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DGAT1 protects tumor from lipotoxicity, emerging as a promising metabolic target for cancer therapy by Xiang Cheng, Feng Geng, Deliang Guo

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Natural Product Skatole Ameliorates Lipotoxicity-Induced Multiple Hepatic Damage under Hyperlipidemic Conditions in Hepatocytes by Sin-Hyoung Hong, Yeonhee Hong, Minji Lee, Byeong-Rak Keum, Gun-Hwa Kim

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Targeting Mitochondrial ROS-Mediated Ferroptosis by Quercetin Alleviates High-Fat Diet-Induced Hepatic Lipotoxicity by Jin-Jin Jiang, Guo-Fu Zhang, Jia-Yi Zheng, Ji-Hu Sun, Shi-Bin Ding

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Inhibition of galectin-3 ameliorates the consequences of cardiac lipotoxicity in a rat model of diet-induced obesity by Gema Marín-Royo, Isabel Gallardo, Ernesto Martínez-Martínez, Beatriz Gutiérrez, Raquel Jurado-López, Natalia López-Andrés, Josué Gutiérrez-Tenorio, Eduardo Rial, Marı́a Visitación Bartolomé, María Luisa Nieto, Victoria Cachofeiro

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Heart-Type Fatty Acid Binding Protein Binds Long-Chain Acylcarnitines and Protects against Lipotoxicity by Diana Zelencova-Gopejenko, Melita Videja, Aiga Grandane, Linda Pudnika-Okinčica, Anda Sipola, Karlis Vilks, Maija Dambrova, Kristaps Jaudzems, Edgars Liepinsh

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Assessing fatty acid-induced lipotoxicity and its therapeutic potential in glioblastoma using stimulated Raman microscopy by Yuhao Yuan, Niraj Shah, Mohammad I. Almohaisin, Soumit Saha, Fake Lu

“…Future work will focus on understanding the metabolic mechanism of EPA-induced lipotoxicity to further enhance its anticancer effects.…”
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Correction to: Oleic acid ameliorates palmitic acid induced hepatocellular lipotoxicity by inhibition of ER stress and pyroptosis by Xin Zeng, Min Zhu, Xiaohong Liu, Xuanmin Chen, Yujia Yuan, Lan Li, Jingping Liu, Yanrong Lu, Jingqiu Cheng, Younan Chen

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Effect of Uncaria tomentosa aqueous extract on the response to palmitate-induced lipotoxicity in cultured skeletal muscle cells by Bruna Leticia de Freitas-Marchi, Jeniffer Farias dos Santos, Gustavo Roncoli Reigado, Myrian Thiago Pruschinski Fernandes, Felipe Santiago Chambergo Alcalde, Carla Roberta de Oliveira Carvalho, Viviane Abreu Nunes

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Positive allosteric GABAA receptor modulation counteracts lipotoxicity-induced gene expression changes in hepatocytes in vitro by Elisabeth Rohbeck, Elisabeth Rohbeck, Elisabeth Rohbeck, Corinna Niersmann, Corinna Niersmann, Corinna Niersmann, Karl Köhrer, Thorsten Wachtmeister, Michael Roden, Michael Roden, Michael Roden, Jürgen Eckel, Jürgen Eckel, Tania Romacho, Tania Romacho

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Antagonism Between Saturated and Unsaturated Fatty Acids in ROS Mediated Lipotoxicity in Rat Insulin-Producing Cells by Wiebke Gehrmann, Wiebke Würdemann, Thomas Plötz, Anne Jörns, Sigurd Lenzen, Matthias Elsner

Subjects: “…Lipotoxicity…”
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Wheat germ oil vitamin E cytoprotective effect and its nutrigenomics signature in human hepatocyte lipotoxicity by Desirée Bartolini, Rita Marinelli, Anna Maria Stabile, Tiziana Frammartino, Angela Guerrini, Stefano Garetto, Jacopo Lucci, Anna Migni, Linda Zatini, Giada Marcantonini, Mario Rende, Francesco Galli

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(+)-Lipoic Acid Reduces Lipotoxicity and Regulates Mitochondrial Homeostasis and Energy Balance in an In Vitro Model of Liver Steatosis by Lucia Longhitano, Alfio Distefano, Angela Maria Amorini, Laura Orlando, Sebastiano Giallongo, Daniele Tibullo, Giuseppe Lazzarino, Anna Nicolosi, Amer M. Alanazi, Concetta Saoca, Vincenzo Macaione, M’hammed Aguennouz, Federico Salomone, Emanuela Tropea, Ignazio Alberto Barbagallo, Giovanni Li Volti, Giacomo Lazzarino

“…In this study, we aimed to investigate the effects of lipoic acid on lipotoxicity and mitochondrial dynamics in an in vitro model of liver steatosis. …”
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Lipotoxic Palmitate Impairs the Rate of β-Oxidation and Citric Acid Cycle Flux in Rat Neonatal Cardiomyocytes by Taha Haffar, Ali Akoumi, Nicolas Bousette

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Curcumin Nanoparticles Attenuate Lipotoxic Injury in Cardiomyocytes Through Autophagy and Endoplasmic Reticulum Stress Signaling Pathways by Yue Gu, Huan Xia, Xiao Chen, Jing Li

“…In this study, the anti-lipotoxic injury activity of CUR-loaded nanoparticles (CUR-NPs) and the corresponding mechanism were examined in palmitate (PA)-treated cardiomyocytes. …”
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Antioxidant and anti-inflammatory effects of Chinese propolis during palmitic acid-induced lipotoxicity in cultured hepatocytes by Xiao-Lu Jin, Kai Wang, Qiang-Qiang Li, Wen-Li Tian, Xiao-Feng Xue, Li-Ming Wu, Fu-Liang Hu

“…Here, we investigated whether Chinese propolis (CP) would mitigate PA-induced lipotoxicity in hepatocytes. Total of 20 phenolic compounds were analysed in CP using HPLC-DAD/Q-TOF-MS. …”
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Fenofibrate improves renal lipotoxicity through activation of AMPK-PGC-1α in db/db mice. by Yu Ah Hong, Ji Hee Lim, Min Young Kim, Tae Woo Kim, Yaeni Kim, Keun Suk Yang, Hoon Suk Park, Sun Ryoung Choi, Sungjin Chung, Hyung Wook Kim, Hye Won Kim, Bum Soon Choi, Yoon Sik Chang, Cheol Whee Park

“…Peroxisome proliferator-activated receptor (PPAR)-α, a lipid-sensing transcriptional factor, serves an important role in lipotoxicity. We evaluated whether fenofibrate has a renoprotective effect by ameliorating lipotoxicity in the kidney. …”
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