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An autologous blood-derived patch as a hemostatic agent: evidence from thromboelastography experiments and a porcine liver punch biopsy model
Published 2023-04-01“…We also evaluated the patch in vivo in a porcine liver punch biopsy model. In this surgical model we saw 100% effective hemostasis and a significant reduction of the time-to-hemostasis, when compared to controls. …”
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An in vivo comparison of the efficacy of hemostatic powders, using two porcine bleeding models
Published 2017-11-01“…The amount of powder applied within the ranges used did not appear to affect hemostatic efficacy.Conclusion: In both the liver punch biopsy model of mild to moderate bleeding and the liver abrasion model of mild but diffuse oozing, SP provided more effective hemostasis and faster TTH than other marketed hemostatic powders. …”
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A polymer‐based systemic hemostat for managing uncontrolled bleeding
Published 2023-05-01“…When applied topically on liver punch biopsy wounds in heparinized rats, HAPPI achieved a 73% of reduction in blood loss and a five‐fold increase in survival rate. …”
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