Anti-IgLON5 antibodies cause progressive behavioral and neuropathological changes in mice by You Ni, Yifan Feng, Dingding Shen, Ming Chen, Xiaona Zhu, Qinming Zhou, Yining Gao, Jun Liu, Qi Zhang, Yuntian Shen, Lisheng Peng, Zike Zeng, Dou Yin, Ji Hu, Sheng Chen

“…A wide range of behaviors, including tests of locomotion, coordination, memory, anxiety, depression and social interactions were established. …”
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Simulating capture efficiency of pitfall traps based on sampling strategy and the movement of ground‐dwelling arthropods by Danish A. Ahmed, Ayah Beidas, Sergei V. Petrovskii, Joseph D. Bailey, Michael B. Bonsall, Amelia S. C. Hood, John A. Byers, Emma J. Hudgins, James C. Russell, Jana Růžičková, Thomas W. Bodey, David Renault, Elsa Bonnaud, Phillip J. Haubrock, Ismael Soto, Peter Haase

“…We contextualise our results by considering the locomotion of Pterostichus melanarius, a highly active carabid beetle often serving as a biocontrol agent for the suppression of pest insects and weeds. …”
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Impact of miR-29c-3p in the Nucleus Accumbens on Methamphetamine-Induced Behavioral Sensitization and Neuroplasticity-Related Proteins by Hang Su, Li Zhu, Linlan Su, Min Li, Rui Wang, Jie Zhu, Yanjiong Chen, Teng Chen

“…Our focus extended to the number of neuronal branches, the excitatory synapse count, and locomotion-related pathways. Notably, GPR37, NPC1, and IREB2 emerged as potential target molecules for miR-29c-3p regulation, suggesting their involvement in the modulation of METH sensitization. …”
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Evaluation of the effects of the T-type calcium channel enhancer SAK3 in a rat model of TAF1 deficiency by Chinnasamy Dhanalakshmi, Udaiyappan Janakiraman, Aubin Moutal, Kohji Fukunaga, Rajesh Khanna, Mark A. Nelson

“…Oral administration of SAK3 (0.25 mg/kg, p.o.) significantly rescued locomotion abnormalities associated with TAF1 gene editing. …”
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Combined Subthalamic and Nigral Stimulation Modulates Temporal Gait Coordination and Cortical Gait-Network Activity in Parkinson’s Disease by Jonas R. Wagner, Miriam Schaper, Wolfgang Hamel, Manfred Westphal, Christian Gerloff, Andreas K. Engel, Christian K. E. Moll, Alessandro Gulberti, Alessandro Gulberti, Monika Pötter-Nerger

“…During STN DBS, FoG was associated with an increase in cortical alpha and low-beta activity over central cortical areas, while with STN+SN DBS, an increase in high-beta was prominent over more frontal areas.ConclusionsSTN+SN DBS improved temporal aspects of parkinsonian gait impairment compared to conventional STN DBS and differentially affected cortical oscillatory patterns during regular locomotion and freezing suggesting a potential modulatory effect on dysfunctional cortical-subcortical communication in PD.…”
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Postadychute-AG, Detection, and Prevention of the Risk of Falling Among Elderly People in Nursing Homes: Protocol of a Multicentre and Prospective Intervention Study by Flavien Quijoux, Flavien Quijoux, François Bertin-Hugault, Philippe Zawieja, Marie Lefèvre, Pierre-Paul Vidal, Pierre-Paul Vidal, Damien Ricard, Damien Ricard, Damien Ricard

“…During the entire duration of the follow-up, they will benefit from a monthly measurement of their postural and locomotion capacities through a recording of their static balance and gait thanks to a software developed for this purpose. …”
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Immunomodulatory effects of new phytotherapy on human macrophages and TLR4- and TLR7/8-mediated viral-like inflammation in mice by Olesia Schapovalova, Olesia Schapovalova, Anna Gorlova, Anna Gorlova, Anna Gorlova, Johannes de Munter, Elisaveta Sheveleva, Elisaveta Sheveleva, Mikhail Eropkin, Nikita Gorbunov, Michail Sicker, Aleksei Umriukhin, Sergiy Lyubchyk, Sergiy Lyubchyk, Klaus-Peter Lesch, Klaus-Peter Lesch, Tatyana Strekalova, Tatyana Strekalova, Tatyana Strekalova, Tatyana Strekalova, Careen A. Schroeter

“…The IP-treated mice injected with LPS showed normalized locomotion, anxiety, and exploration behaviors but not abnormal forced swimming. …”
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Continuous Myoelectric Prediction of Future Ankle Angle and Moment Across Ambulation Conditions and Their Transitions by Erika V. Zabre-Gonzalez, Lara Riem, Philip A. Voglewede, Barbara Silver-Thorn, Barbara Silver-Thorn, Sara R. Koehler-McNicholas, Sara R. Koehler-McNicholas, Scott A. Beardsley

“…A hallmark of human locomotion is that it continuously adapts to changes in the environment and predictively adjusts to changes in the terrain, both of which are major challenges to lower limb amputees due to the limitations in prostheses and control algorithms. …”
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Pharmacological Prevention of Neonatal Opioid Withdrawal in a Pregnant Guinea Pig Model by Alireza Safa, Allison R. Lau, Sydney Aten, Karl Schilling, Karen L. Bales, Victoria A. Miller, Julie Fitzgerald, Min Chen, Kasey Hill, Kyle Dzwigalski, Karl Obrietan, Mitch A. Phelps, Wolfgang Sadee, Wolfgang Sadee, John Oberdick

“…Prenatal MTD significantly aggravates two classic maternal separation stress behaviors in newborn guinea pigs: calling (vocalizing) and searching (locomotion) - natural attachment behaviors thought to be controlled by the endogenous opioid system. …”
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Decreased number of striatal cholinergic interneurons and motor deficits in dopamine receptor 2-expressing-cell-specific Dyt1 conditional knockout mice by Fumiaki Yokoi, Janneth Oleas, Hong Xing, Yuning Liu, Kelly M. Dexter, Carly Misztal, Melinda Gerard, Iakov Efimenko, Patrick Lynch, Matthew Villanueva, Raul Alsina, Shiv Krishnaswamy, David E. Vaillancourt, Yuqing Li

“…Moreover, the Dyt1 d2KO male mice showed significant correlations between striatal monoamines and locomotion. The results suggest that torsinA in the D2R-expressing cells play a critical role in the development or survival of the striatal cholinergic interneurons, expression of striatal D2R mature form, and motor performance. …”
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The CD2v protein of African swine fever virus inhibits macrophage migration and inflammatory cytokines expression by downregulating EGR1 expression through dampening ERK1/2 activit... by Min Zhang, Lilei Lv, Huaye Luo, Hongming Cai, Lingxue Yu, Yifeng Jiang, Fei Gao, Wu Tong, Liwei Li, Guoxin Li, Yanjun Zhou, Guangzhi Tong, Changlong Liu

“…Further analysis indicated that EGR1 and H3K27ac co-occupy the promoter regions of cell locomotion-related genes. Finally, by treating various derivatives of swine macrophages with lipopolysaccharides, we showed that depletion of EGR1 decreased the expression of inflammatory cytokines including TNFα, IL1α, IL1β, IL6, and IL8, which play essential roles in inflammation and host immune response. …”
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Preliminary Study on the Connection Between the Mineral Profile of Horse Hooves and Tensile Strength Based on Body Weight, Sex, Age, Sampling Location, and Riding Disciplines by Gabriel Rueda-Carrillo, René Rosiles-Martínez, Anaid Ireri Hernández-García, Einar Vargas-Bello-Pérez, Francisco J. Trigo-Tavera

“…Hoof mineral profile is important as it could affect locomotion. Factors such as body weight, sex, age, and riding disciplines affect hoof mineral profile. …”
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ADGRA1 negatively regulates energy expenditure and thermogenesis through both sympathetic nervous system and hypothalamus–pituitary–thyroid axis in male mice by Xiao-Hong Zhang, Ling-Yun Tang, Xi-Yi Wang, Chun-Ling Shen, Wen-Feng Xiong, Yan Shen, Ying-Han Wan, You-Bing Wu, Yi-Cheng Wang, Hong-Xin Zhang, Shun-Yuan Lu, Jian Fei, Zhu-Gang Wang

“…The results show that Adgra1 −/− male mice exhibit decreased body weight with normal food intake and locomotion, shrinkage of body mass, increased lipolysis, and hypermetabolic activity. …”
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Acute Thermoregulatory and Cardiovascular Response to Submaximal Exercise in People With Multiple Sclerosis by Elisa Gervasoni, Rita Bertoni, Denise Anastasi, Claudio Solaro, Rachele Di Giovanni, Erica Grange, Hanns-Christian Gunga, Marco Rovaris, Davide Cattaneo, Davide Cattaneo, Martina Anna Maggioni, Martina Anna Maggioni, Giampiero Merati, Giampiero Merati

“…Rather, this appears to be a consequence of the known increased energy cost of locomotion in PwMS.…”
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Communal nesting differentially attenuates the impact of pre-weaning social isolation on behavior in male and female rats during adolescence and adulthood by Jessica Bratzu, Maria Ciscato, Augusta Pisanu, Giuseppe Talani, Roberto Frau, Patrizia Porcu, Marco Diana, Fabio Fumagalli, Patrizia Romualdi, Laura Rullo, Viviana Trezza, Roberto Ciccocioppo, Fabrizio Sanna, Liana Fattore

“…Interestingly, ESI and CN did not have a significant impact on burying behavior in adult animals of both sexes.DiscussionOverall, our findings (i) assess the effects of ESI on locomotion, sensorimotor gating, and compulsive-like behaviors, (ii) reveal distinct vulnerabilities of males and females within these domains, and (iii) show how early-life social enrichment may successfully counteract some of the behavioral alterations induced by early-life social stress in a sex-dependent manner. …”
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Mobile Robotic Balance Assistant (MRBA): a gait assistive and fall intervention robot for daily living by Lei Li, Ming Jeat Foo, Jiaye Chen, Kuan Yuee Tan, Jiaying Cai, Rohini Swaminathan, Karen Sui Geok Chua, Seng Kwee Wee, Christopher Wee Keong Kuah, Huiting Zhuo, Wei Tech Ang

“…Abstract Background Aging degrades the balance and locomotion ability due to frailty and pathological conditions. …”
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Thrombin acts as inducer of proinflammatory macrophage migration inhibitory factor in astrocytes following rat spinal cord injury by Ting Yang, Haiyan Jiang, Xinye Luo, Yuxuan Hou, Aicheng Li, Bingqiang He, Xingyuan Zhang, Huifei Hao, Honghua Song, Rixin Cai, Xudong Wang, Yingjie Wang, Chun Yao, Lei Qi, Yongjun Wang

“…Administration of PAR1 inhibitor at lesion sites following SCI significantly reduced the protein levels of MIF and ameliorated functional deficits of rat locomotion. Conclusion SCI-activated thrombin is a robust inducer of MIF production from astrocytes. …”
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Anodal and cathodal transcranial direct current stimulations of prefrontal cortex in a rodent model of Alzheimer’s disease by Mengsi Duan, Zhiqiang Meng, Zhiqiang Meng, Zhiqiang Meng, Dong Yuan, Yunfan Zhang, Tao Tang, Zhuangfei Chen, Yu Fu

“…Behaviorally, atDCS and ctDCS improved spatial learning and/or memory in AD mice without affecting their general locomotion and anxiety-like behaviors, but the effects depended on the testing paradigms. …”
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Multimodal Evaluation of TMS - Induced Somatosensory Plasticity and Behavioral Recovery in Rats With Contusion Spinal Cord Injury by Vijai S. Krishnan, Vijai S. Krishnan, Vijai S. Krishnan, Vijai S. Krishnan, Samuel S. Shin, Visar Belegu, Visar Belegu, Pablo Celnik, Mark Reimers, Mark Reimers, Kylie R. Smith, Kylie R. Smith, Galit Pelled, Galit Pelled, Galit Pelled, Galit Pelled, Galit Pelled

“…Behavior, motor and sensory functions were tested in three groups: SCI rats that received high-frequency (20 Hz) rTMS within 10 min post-injury (acute-TMS; n = 7); SCI rats that received TMS starting 2 weeks post-injury (chronic-TMS; n = 5), and SCI rats that received sham TMS (no-TMS, n = 5). Locomotion was evaluated by the Basso, Beattie, and Bresnahan (BBB) and gridwalk tests. …”
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The experience of sensorimotor integration of a lower limb sensory neuroprosthesis: A qualitative case study by Melissa S. Schmitt, Melissa S. Schmitt, John D. Wright, Ronald J. Triolo, Ronald J. Triolo, Hamid Charkhkar, Hamid Charkhkar, Emily L. Graczyk, Emily L. Graczyk

“…Successful sensorimotor integration of the SNP resulted in improvements to locomotion, a return to a more normal state, an enhancement of perceived prosthesis utility, and a positive outlook on the experience.DiscussionThese outcomes emerged over the course of the nearly 8 month study, suggesting that findings from long-term home studies of SNPs may differ from those of short-term in-laboratory tests. …”
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