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Exploring the Relationship between Diamine Oxidase and Psychotropic Medications in Fibromyalgia Treatment, Finding No Reduction in Diamine Oxidase Levels and Activity except with C...
Published 2024-01-01“…<b>Results</b>: Notably, the examined drugs—sertraline, pregabalin, paroxetine, alprazolam, and lorazepam—did not exhibit inhibitory effects on DAO activity or lead to reductions in DAO levels. …”
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182
Factors influencing delayed clearance of high dose methotrexate (HDMTX) in pediatric, adolescent, and young adult oncology patients
Published 2023-10-01“…Increased TTC was associated with increasing age (RR 1.02, p<0.0001), higher 24-hour MTX levels (RR 1.001, p=0.012) and 48-hour MTX levels (RR 1.02, p<0.0001), RT (RR 1.004, p<0.0001), use of IV lorazepam (RR 1.08, p=0.001) and IV metoclopramide (RR 1.08, p<0.001) both on day 3. …”
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183
Características sociodemográficas, clínicas y perfil de riesgo anticolinérgico en una residencia sociosanitaria pública: estudio descriptivo
Published 2024-03-01“…Los principios activos con actividad anticolinérgica y/o sedante más frecuentemente prescritos fueron lorazepam, tramadol, tamsulosina y trazodona. El delirio y la ansiedad, junto con las infecciones de repetición del tracto urinario, fueron más prevalentes en el grupo de residentes que presentaban carga anticolinérgica (p<0,05). …”
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184
Alcohol Withdrawal Severity Measures for Identifying Patients Requiring High-Intensity Care
Published 2024-03-01“…The OR increased above 1.0 at a 24-hour lorazepam milligram equivalent dose cutoff of 15 mg. …”
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185
Utilization of psychotropic medicines in Romania during 1998–2018
Published 2023-03-01“…Diazepam lost popularity over time in detriment of the utilization of other anxiolytic benzodiazepines, such as alprazolam and lorazepam. ADs utilization markedly increased during the study period (the average annual growth rate was 13.66% starting 1999). …”
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186
Refining medical clearance protocol for patients with primary psychiatric complaints in the emergency department
Published 2023-07-01“…Most common intervention was intravenous (IV) fluids (n = 59; 45%) followed by admission to other service (n = 15; 8.4%), imaging (n = 10; 7.6%), antihypertensive medication (n = 3; 3.1%), cardiac workup (n = 3; 2.3%), antibiotics (n = 3; 2.3%), lorazepam for undocumented reasons (n = 2; 1.5%). Additional interventions completed once included immunizations, antiseizure medication, pain medication, and additional lab work. …”
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187
LAMOTRIGINE INDUCED LEUCOPENIA IN A PATIENT WITH TYPE 2 BIPOLAR DISEASE
Published 2023-03-01“…We started valproate 500 mg/d and on the 27th day of her stay, she was discharged with a euthymic mood, having no depressive symptoms or suicidal thoughts.Her last treatment was venlafaxine 225 mg, quetiapine XR 300 mg, quetiapine IR 100 mg, valproate 500 mg, lorazepam 1 mg daily. Methods It is a retrospective review. …”
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188
Exploring the intravenous narcotics and controlled drugs wastage and their financial impact: A descriptive single-center study
Published 2023-03-01“…The controlled medications included Midazolam, Phenobarbital, Diazepam, Ketamine and Lorazepam. The annual consumption and wastage of the narcotic and controlled medications were documented using data report generated by narcotics and controlled medication in-charge pharmacist through the hospital’s online system. …”
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189
Prevalence, country-specific prescribing patterns and determinants of benzodiazepine use in community-residing older adults in 7 European countries
Published 2024-03-01“…The most frequently prescribed BZDs were diazepam (27.9% of 426 BZD users), alprazolam (23.7%), bromazepam (22.8%) and lorazepam (16.7%). Independent factors associated with BZD use were female gender (OR 1.58, 95%CI 1.19–2.10), hyperpolypharmacy (OR 1.97, 95%CI 1.22–3.16), anxiety (OR 4.26, 95%CI 2.86–6.38), sleeping problems (OR 4.47, 95%CI 3.38–5.92), depression (OR 1.95, 95%CI 1.29–2.95), repetitive anxious complaints (OR 1.77, 95%CI 1.29–2.42), problems with syncope (OR 1.78, 95%CI 1.03–3.06), and loss of appetite (OR 0.60, 95%CI 0.38–0.94). …”
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190
High-Dose Benzodiazepines Positively Modulate GABA<sub>A</sub> Receptors via a Flumazenil-Insensitive Mechanism
Published 2021-12-01“…Midazolam, clonazepam, and lorazepam at 200 µM exhibited similar flumazenil-insensitive effects on the α<sub>1</sub>β<sub>2</sub>γ<sub>2</sub>, α<sub>2</sub>β<sub>2</sub>γ<sub>2</sub> and α<sub>5</sub>β<sub>2</sub>γ<sub>2</sub> receptors, whereas the potentiation induced by 200 µM zolpidem or triazolam was abolished by flumazenil. …”
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191
GPR68-ATF4 signaling is a novel prosurvival pathway in glioblastoma activated by acidic extracellular microenvironment
Published 2024-01-01“…Notably GPR68, an acid sensing GPCR, is upregulated in radioresistant GBM. Usage of Lorazepam, which has off target agonism of GPR68, is linked to worse clinical outcomes for a variety of cancers. …”
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192
Comorbidities, symptoms and end-of-life medication use in hospitalised decedents before and during the COVID-19 pandemic: a retrospective regional cohort study in Ottawa, Canada
Published 2023-09-01“…COVID+ve group decedents used highest lorazepam and propofol doses.Conclusions COVID-19 decedents, particularly those in ICU, required higher EoL opioid and sedating medication doses than matched prepandemic or intrapandemic controls. …”
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193
Consciously Choosing Unconsciousness
Published 2024-03-01“…For instance, benzodiazepines such as midazolam and lorazepam, commonly employed in palliative sedation, act as central nervous system depressants. …”
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194
Homeward
Published 2022-04-01“…The involuntary jerking had stopped and he only had some pain when turning. Methadone, lorazepam, and haloperidol were held. For the next nine days, we titrated the KFM. …”
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195
Dergilerden Özetler
Published 1997-10-01“…Bu örneğin gaz kromotografisi-kütle spektrofotometri ile yapılan analizinde içinde lorazepam ve temazepam bulunduğu saptanmıştır. Bu bebekte ani solunum durması episodları üstüne belirtilen benzodiazepamların rolü bilinmemektedir. …”
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196
Dergilerden Özetler
Published 1997-10-01“…Bu örneğin gaz kromotografisi-kütle spektrofotometri ile yapılan analizinde içinde lorazepam ve temazepam bulunduğu saptanmıştır. Bu bebekte ani solunum durması episodları üstüne belirtilen benzodiazepamların rolü bilinmemektedir. …”
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