Subclinical Left Ventricular Dysfunction Detected by Speckle-Tracking Echocardiography in Breast Cancer Patients Treated With Radiation Therapy: A Six-Month Follow-Up Analysis (MED... by Médéa Locquet, Daan Spoor, Anne Crijns, Pim van der Harst, Arantxa Eraso, Ferran Guedea, Manuela Fiuza, Susana Constantino Rosa Santos, Stephanie Combs, Kai Borm, Elie Mousseaux, Umit Gencer, Guy Frija, Elisabeth Cardis, Elisabeth Cardis, Elisabeth Cardis, Hans Langendijk, Sophie Jacob

“…It is therefore of primary importance to early detect subclinical left ventricular (LV) dysfunction in BC patients after RT and to determine the dose–response relationships between cardiac doses and these events.MethodsWithin the frame of the MEDIRAD European project (2017–2022), the prospective multicenter EARLY‐HEART study (ClinicalTrials.gov Identifier: NCT03297346) included chemotherapy naïve BC women aged 40–75 years and treated with lumpectomy and adjuvant RT. Myocardial strain analysis was provided using speckle‐tracking echocardiography performed at baseline and 6 months following RT. …”
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2196 Pre-treatment sleep disturbance as a risk factor for radiation therapy induced pain in 676 women with breast cancer by Anita R. Peoples, Wilfred R. Pigeon, Dongmei Li, Joseph A. Roscoe, Sheila N. Garland, Michael L. Perlis, Vincent P. Vinciguerra, Thomas Anderson, Lisa S. Evans, James L. Wade, Deborah J. Ossip, Gary R. Morrow, Julie R. Wolf

“…RESULTS/ANTICIPATED RESULTS: Prior to the start of RT, breast cancer patients with moderate-severe disturbed sleep at baseline were younger, less likely to have had lumpectomy or partial mastectomy while more likely to have had total mastectomy and chemotherapy, more likely to be on sleep, anti-anxiety/depression, and prescription pain medications, and more likely to suffer from depression or anxiety disorder than the control group (all p’s≤0.02). …”
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Automated contouring and statistical process control for plan quality in a breast clinical trial by Hana Baroudi, Callistus I. Huy Minh Nguyen, Sean Maroongroge, Benjamin D. Smith, Joshua S. Niedzielski, Simona F. Shaitelman, Adam Melancon, Sanjay Shete, Thomas J. Whitaker, Melissa P. Mitchell, Isidora Yvonne Arzu, Jack Duryea, Soleil Hernandez, Daniel El Basha, Raymond Mumme, Tucker Netherton, Karen Hoffman, Laurence Court

“…Materials and methods: A deep learning auto-contouring model was created and tested quantitatively and qualitatively on 104 post-lumpectomy patients’ computed tomography images (nnUNet; train/test: 80/20). …”
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Development and external validation of a nomogram to predict four or more positive nodes in breast cancer patients with one to three positive sentinel lymph nodes by Zhuanbo Yang, Xiaowen Lan, Zhou Huang, Yong Yang, Yu Tang, Hao Jing, Jianyang Wang, Jianghu Zhang, Xiang Wang, Jidong Gao, Jing Wang, Lixue Xuan, Yi Fang, Jianming Ying, Yexiong Li, Xiaobo Huang, Shulian Wang

“…The inclusion criteria were: invasive breast cancer; clinically node negative; received lumpectomy or mastectomy plus SLN biopsy followed by axillary lymph node dissection (ALND); and pathologically confirmed T1-2 tumor, with 1–3 positive SLNs. …”
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TTF-1 Positive Primary Small Cell Carcinoma of the Breast: A Case Report and Review of the Literature by Hinda Boutrid, Hinda Boutrid, Mahmoud Kassem, Mahmoud Kassem, Gary Tozbikian, Evan Morgan, Evan Morgan, Julia White, Julia White, Manisha Shah, Manisha Shah, Jeffrey Vandeusen, Jeffrey Vandeusen, Sagar Sardesai, Sagar Sardesai, Nicole Williams, Nicole Williams, Daniel G. Stover, Daniel G. Stover, Maryam Lustberg, Maryam Lustberg, Robert Wesolowski, Robert Wesolowski, Vinay Pudavalli, Terence M. Williams, Bhavana Konda, Stephanie Fortier, David Carbone, Bhuvaneswari Ramaswamy, Bhuvaneswari Ramaswamy, Mathew A. Cherian, Mathew A. Cherian

“…She underwent a right lumpectomy with axillary lymph node dissection and was treated with adjuvant cisplatin-based chemotherapy and concurrent radiation therapy. …”
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Canine mammary anaplastic carcinoma with concurrent aorto-iliac thrombosis in a dog: a case report by J.H. Kim, W.J. Kim, J. Park, J.I. Shin, H.Y. Yoon

“…An 11-year-old, 6.75 kg, spayed female Maltese dog was referred for evaluation of a recurrent mammary gland tumour (MGT) after recent lumpectomies. We performed a regional mastectomy, and the mammary gland tumour was diagnosed as a mammary anaplastic carcinoma. …”
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Oncoplastic Breast Surgery in Early Breast Cancer by Ahmed T. Abdelaziz*, Mahmoud A. Mahmoud, Asmaa G. Rizk, Mohammed A. Negm

“…For huge, inadequately characterized, or ominously arranged tumors, standard lumpectomies may prompt unsuitable restorative outcomes notwithstanding close or included resection edges. …”
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Synchronous bilateral breast cancer with different histology by Marwan Al Marwani, MD, SSC-Rad, Nasser Alamri, MD, Abdullah Allebdi, MD

“…The right breast mass was a Nottingham grade I invasive carcinoma with a mucinous component. After lumpectomies ultrasonography of the surgical specimens confirmed a small biopsy-proven invasive ductal cancer hypoechoic mass in the left breast, with an irregular margins and proven mucinous cancer mass in the right breast. …”
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An Efficient Breast Cancer Segmentation System based on Deep Learning Techniques by Shaaban M. Shaaban, Majid Nawaz, Yahia Said, Mohammad Barr

“…Early detection of breast cancer allows medical professionals to use less intrusive treatments, such as lumpectomies or targeted medicines, improving survival rates and lowering morbidity. …”
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Recurrent giant fibroadenomas with transformation to cystosarcoma phyllodes in a 17-year-old girl: a rare case report from Syria by Sawsan Ismail, Sara Alaidi, Sarah Jouni, Yahya Kassab, Zuheir Al-Shehabi

“…The patient underwent lumpectomies followed by adjuvant radiotherapy. Long-term follow-up was recommended. …”
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Evaluation of 2014 margin guidelines on re-excision and recurrence rates after breast conserving surgery: A multi-institution retrospective study by Anne Kuritzky, Chantal Reyna, Kandace P. McGuire, Weihong Sun, Sara M. DeSnyder, Staci Aubry, Apoorve Nayyar, Paula Strassle, Kelly K. Hunt, Jun-Min Zhou, Marie Catherine Lee

“…Results: 542 patients (545 lumpectomies) were eligible. Using a ≥2 mm margin standard, 32.8% of patients underwent re-excision compared to 14.1% after 2014 (p < 0.0001). …”
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Impact of Mastectomy on Body Image and Sexuality from a LGBTQ Perspective: A Narrative Review by Magdalena Skórzewska, Andrzej Kurylcio, Karol Rawicz-Pruszyński, Wachirabhorn Chumpia, Buabongkoj Punnanan, Sasiwan Jirapongvanich, Tianxiao Jiang, Jerzy Mielko

“…Heterosexual and lesbian female patients are willing to undergo mastectomy after repeated lumpectomies or to avoid radiation, despite potential post-operative somatic and quality-of-life complications. …”
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Leverage of an Existing Cervical Cancer Prevention Service Platform to Initiate Breast Cancer Control Services in Zambia: Experiences and Early Outcomes by Leeya F. Pinder, Ronda Henry-Tillman, David Linyama, Victor Kusweje, Jean-Baptiste Nzayisenga, Aaron Shibemba, Vikrant Sahasrabuddhe, Kennedy Lishimpi, Mulindi Mwanahamuntu, Michael Hicks, Groesbeck P. Parham

“…Newly trained surgeons performed six sentinel lymph node mappings, eight sentinel lymph node dissections, and 10 breast conservation surgeries (lumpectomies). Conclusion: This initiative successfully established clinical services in Zambia that are critical for the early detection and surgical management of breast cancer.…”
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429 Spatial Investigation of the Extracellular Matrix Metastatic Niche in Invasive Breast Cancer by Mass Spectrometry Imaging by Taylor S Hulahan, Yeonhee Park, Laura Spruill, Hari Nakshatri, Marvella Ford, Peggi M Angel

“…METHODS/STUDY POPULATION: Lymph node metastases were compared to patient-matched primary tumor and normal lymph nodes using tissue microarrays (TMA) from 31 generational South Carolina women with IBC (black women, BW n=10, white women, WW n=21) and lumpectomies from 5 triple-negative breast cancer (TNBC) patients (BW n=3; WW n=2) by ECM-targeted mass spectrometry imaging. …”
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TRAM flap in reconstructive operations in patients with breast cancer by A. D. Zikiryakhodzhaev, E. A. Rasskazova

“…The volume of its operations varies from radical mastectomies to lumpectomies and, in the areas of regional metastases, from three-level lymphadenectomy to sentinel lymph node biopsy. …”
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Surgical Management of Cardiac Masses in Right Atrium Among Bone Sarcoma Pediatric Patients With Totally Implanted Ports by Chenliang Zhou, Yiyun Wang, Zonghui Chen, Guowei Qian, Wenxi Yu, Yong Wang, Shuier Zheng, Zan Shen, Hongtao Li, Yonggang Wang

“…Four patients with good response to anti-tumor treatment had received surgical lumpectomies for pathologic identification and mass excision, with cardiac metastases among 1 patient and thromboses among 3 patients. …”
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Preserving Nipple Sensitivity after Breast Cancer Surgery: A Systematic Review and Meta-Analysis by Varsha Harish, Zoe K. Haffner, Jenna C. Bekeny, Adaah A. Sayyed, David H. Song, Kenneth L. Fan

“…This study aims to evaluate the current understanding of nipple-areolar complex (NAC) sensation outcomes in breast cancer patients undergoing breast cancer surgeries, namely, nipple-sparing mastectomies (NSM), skin-sparing mastectomies (SSM), and lumpectomies. Methods. Articles including terms related to “nipple,” “mastectomy,” “sensation,” and “patient-reported outcome” were queried from three databases according to PRISMA guidelines. …”
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