Molecular and spatial analysis of tertiary lymphoid structures in Sjogren’s syndrome by Nayar, S, Turner, JD, Asam, S, Fennell, E, Pugh, M, Colafrancesco, S, Berardicurti, O, Smith, CG, Flint, J, Teodosio, A, Iannizzotto, V, Gardner, DH, van Roon, J, Korsunsky, I, Howdle, D, Frei, AP, Lassen, KG, Bowman, SJ, Ng, W, Croft, AP, Filer, A, Fisher, BA, Buckley, CD, Barone, F

“…Tertiary lymphoid structures play important roles in autoimmune and non-autoimmune conditions. …”

Perturbation of fetal liver hematopoietic stem and progenitor cell development by trisomy 21 by Roy, A, Cowan, G, Mead, AJ, Filippi, S, Bohn, G, Chaidos, A, Tunstall, O, Chan, JKY, Choolani, M, Bennett, P, Kumar, S, Atkinson, D, Wyatt-Ashmead, J, Hu, M, Stumpf, MPH, Goudevenou, K, O'Connor, D, Chou, ST, Weiss, MJ, Karadimitris, A, Jacobsen, SE, Vyas, P, Roberts, I

“…In lymphopoiesis, T21 FL lymphoid-primed multipotential progenitors and early lymphoid progenitor numbers are maintained, but there was a 10-fold reduction in committed PreproB-lymphoid progenitors and the functional B-cell potential of HSC and early lymphoid progenitor is severely impaired, in tandem with reduced early lymphoid gene expression. …”

Paracrine provision of lipids in the immune system by Pond, C

“…Dendritic cells and lymph node lymphoid cells obtain many, possibly all, fatty acids found in structural lipids from adjacent perinodal adipocytes. …”

Emerging roles of downstream of kinase 3 in cell signaling by Loh, Jia Tong, Teo, Joey Kay Hui, Lim, Hong-Hwa, Lam, Kong-Peng

“…Emerging data further demonstrate that Dok-3 can act both as an activator and inhibitor, in lymphoid and non-lymphoid cell types, suggesting Dok-3 involvement in a plethora of signal transduction pathways. …”
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Tropism of subgroup J avian leukosis virus as detected by in situ hybridization by Arshad, S. S., Smith, L. M., Howes, K., Russell, P. H., Venugopal, K., Payne, L. N.

“…Higher levels of viral gene expression in the bursa of Fabricius infected with RAV-1, but not with HPRS-103, might help explain the inability of the latter virus to induce lymphoid leukosis.…”
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Identification and characterisation of the haematopoietic stem/progenitor cells at risk for leukaemia development following radiation exposure by Verbiest, T

“…Finally, we report on a gender-dependent leukaemic progression and characterisation where 3 Gy irradiated male mice only present with acute myeloid leukemia and irradiated female mice mainly develop leukaemia with a lymphoid phenotype. In conclusion, the work in this thesis postulates data obtained from two novel mouse models and which could help to further identify key molecular mechanisms involved in leukaemia initiation and development.…”

Adjuvant COX inhibition augments STING signaling and cytolytic T cell infiltration in irradiated 4T1 tumors by Ridnour, LA, Cheng, RYS, Kedei, N, Somasundaram, V, Bhattacharyya, DD, Basudhar, D, Wink, AL, Walke, AJ, Kim, C, Heinz, WF, Edmondson, EF, Butcher, DO, Warner, AC, Dorsey, TH, Pore, M, Kinders, RJ, Lipkowitz, S, Bryant, RJ, Rittscher, J, Wong, STC, Hewitt, SM, Chang, JC, Shalaby, A, Callagy, GM, Glynn, SA, Ambs, S, Anderson, SK, McVicar, DW, Lockett, SJ, Wink, DA

“…Spatial immunological changes including augmented lymphoid infiltration into the tumor epithelium and locally increased cGAS/STING1 and type I IFN gene expression were observed in radiation-indomethacin–treated 4T1 tumors. …”

Statistical methods and analyses in autoimmune diseases by Inshaw, J

“…I fine mapped each region and confirmed that prioritised variants were enriched in open chromatin re- gions in lymphoid cells. </p> <p>Ongoing and future research aims to go from maps, to mechanisms, to medicines.…”

A Wavelet-Based Approach Reveals Host-Cell-Type-Specific Multi-omics Networks in Inflammatory Bowel Disease by Chang, Stephanie, Shankar, Adeethyia, Zhao, Yongzhong, Liu, Tong, Wang, Xiaodi

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The critical role of IL-23 receptor positive T cells in the pathogenesis of anterior uveitis associated with spondyloarthropathy by Hedley, R

“…However, although work has been done to characterize resident leukocyte populations within the anterior compartment of the eye there has been no documentation of resident lymphoid cells in these tissues and there is no evidence suggesting the presence of a sentinel cell capable of responding to IL-23.…”

Immuno-protective effect of commercial IBD vaccines against emerging novel variant infectious bursal disease virus in specific-pathogen-free chickens by Aliyu, Hayatuddeen Bako, Hamisu, Tasiu Mallam, Hair-Bejo, Mohd, Omar, Abdul Rahman, Ideris, Aini

“…The IBD antibodies (Abs), lymphoid lesions, and viral load were determined. Results: The UPM1432/2019 virus induced bursal damage in vaccinated SPF chickens despite Ab titers. …”
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Dengue Serotype Cross-Reactive, Anti-E Protein Antibodies Confound Specific Immune Memory for 1 Year after Infection by Toh, Ying Xiu, Gan, Victor, Balakrishnan, Thavamalar, Zuest, Roland, Poidinger, Michael, Wilson, Solomonraj, Appanna, Ramapraba, Thein, Tun Linn, Ong, Adrian Kheng-Yeow, Ng, Lee Ching, Leo, Yee Sin, Fink, Katja

“…Dengue infection triggered a massive activation and mobilization of both naïve and memory B cells possibly from lymphoid organs into the blood, providing an explanation for the surge of circulating plasmablasts and the increase in cross-reactive E protein-specific antibodies.…”
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Profiling immune markers for identification of leukocytes in brown-marbled grouper Epinephelus fuscoguttatus (Forsskal, 1775) by Chong, Chou Min

“…With the successfully establishment of the methodologies and reagents in isolation and characterisation of leukocytes subsets in grouper blood and lymphoid organs,in addition to the development of MAB and non-MAb markers, immune responses of the grouper could be monitored against various environmental or biotic stressors and immunoprophylactic treatments that will lead to improvement of programs in aquaculture of brown-marbled grouper.…”
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Vitamin D3 and carbamazepine protect against Clostridioides difficile infection in mice by restoring macrophage lysosome acidification by Chan, Hung, Li, Qing, Wang, Xiansong, Liu, Wing Yingzhi, Hu, Wei, Zeng, Judeng, Xie, Chuan, Kwong, Thomas Ngai Yeung, Ho, Idy Hiu Ting, Liu, Xiaodong, Chen, Huarong, Yu, Jun, Ko, Ho, Chan, Raphael Chiu Yeung, Ip, Margaret, Gin, Tony, Cheng, Alfred Sze Lok, Zhang, Lin, Chan, Matthew Tak Vai, Wong, Sunny Hei, Wu, William Ka Kei

“…Abbreviations: ATP6V0B: ATPase H+ transporting V0 subunit b; ATP6V0C: ATPase H+ transporting V0 subunit c; ATP6V0E1: ATPase H+ transporting V0 subunit e1; ATP6V1H: ATPase H+ transporting V1 subunit H; CBZ: carbamazepine; CDI: C. difficile infection; CXCL: chemokine C-X-X motif ligand; IL: interleukin; LAMP1: lysosomal-associated membrane protein 1; LC3: microtubule-associated protein 1 light chain 3; LEF: lymphoid enhancer binding factor 1; MITF: melanocyte inducing transcription factor; NFKB: nuclear factor kappa B; PMA: phorbol 12-myristate 13-acetate; TcdA: Clostridial toxin A; TcdB: Clostridial toxin B; TFE3: transcription factor E3; TFEB: transcription factor EB.…”
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