Effects of Astragalus membranaceus extract and Eucommia ulmoides leaf extract on growth performance, blood biochemistry, and antioxidant capacity of gibel carp juveniles (Carassius... by Yan Lin, Siyue Lu, Farhan Aye Tahir, Qunlan Zhou, Linghong Miao, Bo Liu, Xianping Ge

“…One-way ANOVA analysis showed that 0.02% AME with different levels of ELE (0.05%, 0.1% and 0.2%) significantly increased FBW, SGR, WGR, the crude protein and crude lipid of whole body, the GLU, TP, ALB, TC, and TG content of the plasma, and the activities of the lysozyme, total superoxide dismutase, and catalase (CAT) of the liver when compared with A0.02E0 diet (Tukey’s test: P < 0.05). …”
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Genes expression in Penaeus monodon of Bangladesh; challenged with AHPND-causing Vibrio parahaemolyticus by Md. Mer Mosharraf Hossain, Nawshin Farjana, Rukaiya Afroz, Hasan-Uj-Jaman, Pobitra Kumar Saha, Hironmoy Shovon Roy, Md. Anisur Rahman, Md. Almamun Farid

“…The immune genes toll-like receptors (TLR), prophenoloxidase (ProPO), lysozyme (lyso), and penaeidin (PEN) of PL20 and PL25 of P. monodon were expressed robustly up-trends. …”
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The Effect of Administration of a Phytobiotic Containing Cinnamon Oil and Citric Acid on the Metabolism, Immunity, and Growth Performance of Broiler Chickens by Magdalena Krauze, Monika Cendrowska-Pinkosz, Paulius Matuseviĉius, Anna Stępniowska, Paweł Jurczak, Katarzyna Ognik

“…Chickens receiving the phytobiotic in the amount of 0.25 mL/L had better growth performance, which was linked to the beneficial effect of the preparation on the microbiome of the small intestine, metabolism (the HDL level <i>p</i> = 0.017 was increased; and a decreased level of total cholesterol (TC) <i>p</i> = 0.018 and nonesterified fatty acids (NEFA) <i>p</i> = 0.007, LDL <i>p</i> = 0.041, as well as triacylglycerols (TAG) <i>p</i> = 0.014), and immune (the level of lysozyme <i>p</i> = 0.041 was increased, as well as the percentage of phagocytic cells <i>p</i> = 0.034, phagocytosis index <i>p</i> = 0.038, and Ig-A level <i>p</i> = 0.031) and antioxidant system (the level of LOOH <i>p</i> < 0.001, MDA <i>p</i> = 0.002, and the activity of Catalase (CAT) <i>p</i> < 0.001 were decreased, but the level of ferric reducing ability of plasma (FRAP) <i>p</i> = 0.029, glutathione <i>p</i> = 0.045 and vitamin C <i>p</i> = 0.021 were increased).…”
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Effect of density stress on the physiological, biochemical, and immunological parameters of juvenile Pelteobagrus fulvidraco during simulated transportation by Chan Bai, Xue Qi, Zhaoding Wang, Juguang Wang, Liang Qiu, Haohua Li, Xiaoyan Zu, Hailan Li, Guangquan Xiong, Tao Liao

“…The results showed that with the prolonged transport time, plasma cortisol (COR), and catalase (CAT), malonaldehyde (MDA) and lysozyme (LZM) levels in the livers first increased and later gradually decreased after 16 h of transport, while the activity of superoxide dismutase (SOD) continued to rise. …”
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Aggregation kinetics of polystyrene nanoplastics in gastric environments: Effects of plastic properties, solution conditions, and gastric constituents by Zhiwei Shao, Jiana Su, Jiawei Dong, Miaoting Liang, Jie Xiao, Jindie Liu, Qiaoyun Zeng, Yongtao Li, Weilin Huang, Chengyu Chen

“…Freundlich isotherm suggested that PSNPs adsorbed organic constituents following lysozyme > porcine bile > proteose-peptone > pepsin > glycine > D-glucose, inducing changes in constituent structure and PSNP properties. …”
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Mulberry leaf extract improves non-specific immunity and antioxidant capacity of largemouth bass (Micropterus salmoides) fed a high-starch diet by Jing Tingsen, Luo Hui, Luo Hui, Huang Junwa, Li Zhe, Li Yu, Jin Honghao, Zou Xinxi, Ke Zhenlin, Sun Wenbo, Hou Mengdan, Yang Huijun, Ye Hua, Ye Hua

“…Supplementation with 0.50% (MLE4) MLE significantly increased the lysozyme (LYZ) content and decreased the activities of alanine transaminase (ALT) and aspartate transaminase (AST). …”
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Effects of dietary supplementation of Bacillus subtilis DSM 32315 on growth, immune response and acute ammonia stress tolerance of Nile tilapia (Oreochromis niloticus) fed with hig... by Zhihong Liao, Yantao Liu, Hanlin Wei, Xuanshu He, Ziqiao Wang, Zhenxiao Zhuang, Wei Zhao, Karthik Masagounder, Juyun He, Jin Niu

“…Compared with the non-supplemented group, 0.1% probiotic supplementation remarkably increased plasma lysozyme activity, total antioxidant capacity and complement C3 and interleukin-10 mRNA levels (P < 0.05) in the 28% protein diet, while higher supplementation of probiotics (0.3%) was shown to be beneficial for the high protein diet (32%). …”
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Physiological responses to heat stress in the liver of rainbow trout (Oncorhynchus mykiss) revealed by UPLC-QTOF-MS metabolomics and biochemical assays by Shanwei Li, Yingjie Liu, Bolun Li, Lu Ding, Xiaofeng Wei, Peng Wang, Zhongxiang Chen, Shicheng Han, Tianqing Huang, Bingqian Wang, Yanchun Sun

“…The results of the biochemical analysis showed that serum aminotransferase, lysozyme, total bilirubin, alkaline phosphatase and liver superoxide dismutase, glutathione peroxidase, and malondialdehyde in rainbow trout under heat stress changed significantly. …”
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Blood indices and immune organs morphological structure of broiler chickens under the influence of different doses of probiotic feed additives by M. Zhyla, N. Shkodyak, O. Pyatnychko, G. Kotsyumbas, N. Lisova, O. Sobodosh, M. Shkil, E. Khmil

“…Stimulating cellular and humoral protection, nonspecific resistance is established, confirmed by a high level of lysozyme activity in blood serum and significantly higher content of T- and B-lymphocytes, NK-cells, and γ-globulins. …”
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Mannan Oligosaccharide Enhanced the Growth Rate, Digestive Enzyme Activity, Carcass Composition, and Blood Chemistry of Thinlip Grey Mullet (<i>Liza ramada</i>) by Fawzy I. Magouz, Mohamed I. Bassuini, Malik M. Khalafalla, Ramy Abbas, Hani Sewilam, Salama Mostafa Aboelenin, Mohamed Mohamed Soliman, Asem A. Amer, Ali A. Soliman, Hien Van Doan, Mahmoud A. O. Dawood

“…The blood globulin was significantly enhanced in fish fed 1% MOS than fish treated with 0, 0.5, and 2% of MOS (<i>p</i> < 0.05). The blood lysozyme activity was meaningfully enhanced by including MOS at 1%, followed by fish treated with 0.5 and 2%, while the lowest values were in the control group (<i>p</i> < 0.05). …”
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Effect of dietary probiotic supplementation on growth and innate immune system in sole (<i>Solea senegalensis</i> Kaup, 1858) subjected to pathogenic bacteria infection and handlin... by Andreia Ferreira Domingues, Andreia Ferreira Domingues, Ana Gomes, Rui Barros, Rodrigo O. A. Ozorio

“…Growth performance and innate immune parameters (peroxidase and lysozyme activities and alternative complement pathway - ACH50) were analyzed.…”
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Targeting the RNA-Binding Protein <i>QKI</i> in Myeloid Cells Ameliorates Macrophage-Induced Renal Interstitial Fibrosis by Ruben G. de Bruin, Gillian Vogel, Jurrien Prins, Jacques M. J. G. Duijs, Roel Bijkerk, Hendrik J. P. van der Zande, Janine M. van Gils, Hetty C. de Boer, Ton J. Rabelink, Anton Jan van Zonneveld, Eric P. van der Veer, Stéphane Richard

“…Using two mouse models, namely (1) <i>quaking</i><i> </i><i>viable</i> mice (<i>qk</i>^v) and (2) the conditional deletion in the myeloid cell lineage using the lysozyme 2-Cre (<i>QKI</i>^{FL/FL;LysM-Cre} mice), we demonstrate that the abrogation of <i>QKI</i> expression in the myeloid cell lineage reduces macrophage infiltration following kidney injury induced by unilateral urethral obstruction (UUO). …”
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TssI2-TsiI2 of Vibrio fluvialis VflT6SS2 delivers pesticin domain-containing periplasmic toxin and cognate immunity that modulates bacterial competitiveness by Yuanming Huang, Yu Han, Zhenpeng Li, Xiaorui Li, Zhe Li, Ping Liu, Xiaoshu Liu, Qian Cheng, Fenxia Fan, Biao Kan, Weili Liang

“…Site-directed mutagenesis demonstrated that, in addition to Glu-844, Thr-863, and Asp-869, which correspond to three reported residues in pesticin of Yersinia pestis, additional residues including Phe-837, Gly-845, Tyr-851, Gly-867, Gln-963, Trp-975, and Arg-1000 were also proved to be crucial to the bactericidal activity of TssI2. Muramidase/lysozyme-related peptidoglycan (PG) hydrolase activities of TssI2 and its variants were validated with permeabilized Escherichia coli cells and purified PG substrate. …”
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Dietary propolis complementation relieves the physiological and growth deterioration induced by Flavobacterium columnare infection in juveniles of common carp (Cyprinus carpio). by Hesham A Hassanien, Yousof N Alrashada, Ahmed O Abbas, Abdelwahab M Abdelwahab

“…At the end of the trial, blood samples were obtained from the fish to evaluate some plasma biochemicals, including aspartate aminotransaminase (AST), alanine aminotransferase (ALT), creatinine (CRE), alkaline phosphatase (ALP), and lactate dehydrogenase (LDH), antioxidant biomarkers, including total antioxidant capacity (TAOC), total superoxide dismutase (TSOD), reduced glutathione (rGSH), and catalase (CAT), stress indicators, including heterophil to lymphocyte (H/L) ratio, cortisol (COR), malondialdehyde (MDA), and myeloperoxidase (MPO), and immunological reactions, including peripheral blood leukocyte proliferation (PBLP), phagocytosis activity (PHG), lysozyme activity (LYS), alternative complement hemolytic action (ACH50), and total immunoglobulin concentration (TIG). …”
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Single-cell Transcriptomics Reveals Early Molecular and Immune Alterations Underlying the Serrated Neoplasia Pathway Toward Colorectal CancerSummary by Yu-Jie Zhou, Xiao-Fan Lu, Huimin Chen, Xin-Yuan Wang, Wenxuan Cheng, Qing-Wei Zhang, Jin-Nan Chen, Xiao-Yi Wang, Jing-Zheng Jin, Fang-Rong Yan, Haoyan Chen, Xiao-Bo Li

“…Epithelial clusters of SSL and TSA showed distinct molecular features: SSL-specific epithelium manifested overexpressed proliferative markers with Notch pathway activation, whereas TSA-specific epithelium showed Paneth cell metaplasia with aberrant lysozyme expression. As for immune contexture, enhanced cytotoxic activity of CD8+ T cells was observed in SLs; it was mainly attributable to increased proportion of CD103+CD8+ tissue-resident memory T cells, which might be regulated by retinoic acid metabolism. …”
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Screening, Purification And Characterization Of Extracellular Lipase Produced By Pediococcus Acidilactici Ub6 Isolated From Malaysian Fermented Foods by Yap, Sia Yen

“…The lipase activity was not significantly affected by Proteinase K, however, it was affected greatly by β-chymotrypsin, α-chymotrypsin, trypsin, papain and lysozyme. The extracellular lipase UB6 was stable in 0-1% (w/v) NaCl. …”
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Characterization of peptides and proteins from epidermal mucus of climbing perch Anabas testudineus (Bloch, 1972) with antibacterial and immunomodulatory properties by Hussein, Agharid Ali

“…Assessment of the immune-related enzymes activities of protease, lysozyme and esterase in bioactive crude indicated significant roles in disease defence mechanism. …”
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Effects of Dietary <i>Eucommia ulmoides</i> Leaf Extract on Growth, Muscle Composition, Hepatopancreas Histology, Immune Responses and Microcystin-LR Resistance of Juvenile Red Cla... by Yao-Peng Lu, Pei-Hua Zheng, Jia-Rui Xu, Yan-Lei Cao, Jun-Tao Li, Chen-Guang Hao, Ze-Long Zhang, Jian-An Xian, Xiu-Xia Zhang, An-Li Wang

“…Dietary ELE significantly increased the relative expression levels of SOD, thioredoxin 1 (TRX1), GPx, selenium-dependent glutathione peroxidase (Se-GPx), cytochrome P450 (CYP450), anti-lipopolysaccharide factor (ALF) and C-type lysozyme (C-LZM) mRNA of crayfish compared with the control group during the feeding experiment. …”
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Dysregulated hepatic lipid metabolism and gut microbiota associated with early-stage NAFLD in ASPP2-deficiency mice by Fang Xie, Fang Xie, Hang-fei Xu, Hang-fei Xu, Jing Zhang, Xiao-ni Liu, Xiao-ni Liu, Bu-xin Kou, Bu-xin Kou, Meng-yin Cai, Meng-yin Cai, Jing Wu, Jin-ling Dong, Qing-hua Meng, Yi Wang, Dexi Chen, Dexi Chen, Yang Zhang, Yang Zhang

“…Moreover, ASPP-deficiency mice exhibited impaired intestinal barrier function, reduced expression of genes associated with chemical barrier (REG3B, REG3G, Lysozyme and IAP), and increased expression of innate immune components (TLR4 and TLR2). …”
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Changes in concentrations of cervicovaginal immune mediators across the menstrual cycle: a systematic review and meta-analysis of individual patient data by Sean M. Hughes, Claire N. Levy, Ronit Katz, Erica M. Lokken, Melis N. Anahtar, Melissa Barousse Hall, Frideborg Bradley, Philip E. Castle, Valerie Cortez, Gustavo F. Doncel, Raina Fichorova, Paul L. Fidel, Keith R. Fowke, Suzanna C. Francis, Mimi Ghosh, Loris Y. Hwang, Mariel Jais, Vicky Jespers, Vineet Joag, Rupert Kaul, Jordan Kyongo, Timothy Lahey, Huiying Li, Julia Makinde, Lyle R. McKinnon, Anna-Barbara Moscicki, Richard M. Novak, Mickey V. Patel, Intira Sriprasert, Andrea R. Thurman, Sergey Yegorov, Nelly Rwamba Mugo, Alison C. Roxby, Elizabeth Micks, Florian Hladik, The Consortium for Assessing Immunity Across the Menstrual Cycle

“…There was minimal change between the phases for CXCL8, 9, and 10, interferons, TNF, SLPI, elafin, lysozyme, lactoferrin, and interleukins 1β, 2, 10, 12, 13, and 17A. …”
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