Structural insights into thrombolytic activity of destabilase from medicinal leech by Egor Marin, Daniil A. Kornilov, Sergey S. Bukhdruker, Vladimir A. Aleksenko, Valentin A. Manuvera, Egor V. Zinovev, Kirill V. Kovalev, Mikhail B. Shevtsov, Anna A. Talyzina, Pavel A. Bobrovsky, Pavel K. Kuzmichev, Alexey V. Mishin, Ivan Y. Gushchin, Vassili N. Lazarev, Valentin I. Borshchevskiy

“…Abstract Destabilase from the medical leech Hirudo medicinalis belongs to the family of i-type lysozymes. It has two different enzymatic activities: microbial cell walls destruction (muramidase activity), and dissolution of the stabilized fibrin (isopeptidase activity). …”
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Cellular and humoral immune response between snail hosts and their parasites by Hanan Al-Khalaifah

“…Several immunological processes are involved in the interactive immune response between snails and their parasites, including phagocytosis, nitric oxide synthesis, phenol oxidase activity, lysozymes, and lectin formation. The immunological responses connected to the interaction between snails and parasites are discussed in detail in the current research. …”
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Study of an active antimicrobial system using a bio-switch concept by Muhammad, Ida Idayu, Razali, Firdausi, Md. Salleh, Liza

“…The objective of this research is to develop a starch-based film incorporated with antimicrobial agents consisting of lysozymes, lauric acid, nisin and EDTA (chelating agent). …”
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Indole produced during dysbiosis mediates host–microorganism chemical communication by Rui-Qiu Yang, Yong-Hong Chen, Qin-yi Wu, Jie Tang, Shan-Zhuang Niu, Qiu Zhao, Yi-Cheng Ma, Cheng-Gang Zou

“…DAF-16 up-regulates two lysozymes lys-7 and lys-8, thus limiting the bacterial accumulation in the gut of worms during aging. …”
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The immature intestinal epithelial cells in preterm infants play a role in the necrotizing enterocolitis pathogenesis: A review by Veronique Demers-Mathieu

“…These characteristics in the preterm intestine include a reduced thickness of mucus, lower intestinal alkaline phosphatase secreted by enterocytes, and diminished secretion of lysozymes by Paneth cells compared to term infants, which increase their risk of inflammation, dysbiosis, and development of necrotizing enterocolitis (NEC). …”
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Study of an antimicrobial starch-based active packaging system by Khairuddin, Nozieana, Mohd. Razi, Aishahtur Radhiah, Muhamad, Ida Idayu

“…A starch-based film was prepared and incorporated with antimicrobial agents consisting of a combination of nisin and lysozymes. This film was then inoculated with the bacteria Escherichia coli and Bacillus subtilis to carry out the microbial contamination study. …”
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Study of an antimicrobial starch-based active packaging system by Khairuddin, Nozieana, Mohd. Razi, Aishahtur Radhiah, Muhamad, Ida Idayu

“…A starch-based film was prepared and incorporated with antimicrobial agents consisting of a combination of nisin and lysozymes. This film was then inoculated with the bacteria Escherichia coli and Bacillus subtilis to carry out the microbial contamination study. …”
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Crystal structure of human alpha-lactalbumin at 1.7 A resolution. by Acharya, K, Ren, J, Stuart, D, Phillips, D, Fenna, R

“…The striking structural resemblance between alpha-lactalbumins and C-type lysozymes emphasizes the homologous evolutionary relationship between these two classes of proteins.…”

Insights into the transcriptome of oenocytes from Aedes aegypti pupae by Gustavo Ferreira Martins, José Marcelo Ramalho-Ortigão, Neil Francis Lobo, David William Severson, Mary Ann McDowell, Paulo Filemon Paolucci Pimenta

“…Moreover, oenocytes expressed several immunity-related genes and the majority of these genes were lysozymes. The transcriptional profile suggests that oenocytes play diverse roles, such as detoxification and lipid metabolism, and increase our understanding of the importance of oenocytes in Ae. aegypti homeostasis and immune competence.…”
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Genomic clusters, putative pathogen recognition molecules, and antimicrobial genes are induced by infection of C. elegans with M. nematophilum. by O'Rourke, D, Baban, D, Demidova, M, Mott, R, Hodgkin, J

“…We also found significant induction of genes encoding lysozymes, proteases, and defense-related proteins, as well as various domains of unknown function. …”

Impaired immune response and barrier function in GSPD-1-deficient C. elegans infected with Klebsiella pneumoniae by Wan-Hua Yang, Po-Hsiang Chen, Hung-Hsin Chang, Hong Luen Kwok, Arnold Stern, Po-Chi Soo, Jiun-Han Chen, Hung-Chi Yang

“…The down-regulation of antimicrobial effector lysozymes, including lys-1, lys-2, lys-7, lys-8, ilys-2 and ilys-3, was found in gspd-1-knockdown C. elegans infected with KP. …”
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Targeted therapy of kidney disease with nanoparticle drug delivery materials by Shunlai Shang, Xiangmeng Li, Haoran Wang, Yena Zhou, Keying Pang, Ping Li, Xiaomin Liu, Min Zhang, Wenge Li, Qinggang Li, Xiangmei Chen

“…The prerequisite for nanomedicine in treating kidney diseases is the use of carriers with good biocompatibility, including nanoparticles, hydrogels, liposomes, micelles, dendrimer polymers, adenoviruses, lysozymes, and elastin-like polypeptides. These carriers have precise renal uptake, longer half-life, and targeted organ distribution, protecting and improving the efficacy of the drugs they carry. …”
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Rapid collapse and slow structural reorganisation during the refolding of bovine alpha-lactalbumin. by Forge, V, Wijesinha, RT, Balbach, J, Brew, K, Robinson, C, Redfield, C, Dobson, C

“…The extent of the exchange protection is, however, small, and there is no evidence for the existence of well-defined discrete kinetic intermediates of the type populated in the refolding of the structurally homologous c-type lysozymes. Rather, both mass spectrometric and NMR data indicate that the rate-determining transition from the compact partially structured (molten globule) species to the native state is highly cooperative. …”

Effects of <i>Barranca yajiagengensis</i> Powder in the Diet of <i>Trachinotus ovatus</i> on the Growth Performance, Antioxidant Capacity, Immunity and Morphology of the Liver and... by Wei Zhao, Xin Cui, Zi-Qiao Wang, Rong Yao, Meng-Die Chen, Bao-Yan Gao, Cheng-Wu Zhang, Jin Niu

“…Furthermore, the BY5 diet improved non-specific immunity and antibacterial ability by activating lysozymes and the complement system and increasing the nitric oxide (NO) content and total nitric oxide synthase activity. …”
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The protective effects of Xuebijing injection on intestinal injuries of mice exposed to irradiation by Yinping Dong, YuanYang Zhang, Xinyue Wang, Wenxuan Li, Junling Zhang, Lu Lu, Hui Dong, Saijun Fan, Aimin Meng, Deguan Li

“…The expression of Lgr5+ intestinal stem cells (ISCs), Ki67+ cells, villin and lysozymes were examined by immunohistochemistry. The expression of cytokines in the intestinal crypt was detected by RT‐PCR. …”
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Flavonoids as Potential Anti-Inflammatory Molecules: A Review by Jameel M. Al-Khayri, Gandasi Ravikumar Sahana, Praveen Nagella, Biljo V. Joseph, Fatima M. Alessa, Muneera Q. Al-Mssallem

“…They inhibit the secretions of enzymes such as lysozymes and β-glucuronidase and inhibit the secretion of arachidonic acid, which reduces inflammatory reactions. …”
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Effect of Dietary Flaxseed Oil Supplementation on the Redox Status, Haematological and Biochemical Parameters of Horses’ Blood by Iwona Sembratowicz, Grzegorz Zięba, Ewelina Cholewinska, Anna Czech

“…Moreover, FO caused an elevation in red blood cell indicators, lymphocyte count and lysozymes. In conclusion, FO exerts a beneficial effect by stimulating antioxidant defence mechanisms of horses and reducing the severity of oxidative stress. …”
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Application of 4 × 44 Oligo Microarray to Transcriptomic Analysis of Immune Response in Rainbow Trout Infected with <i>Aeromonas salmonicida</i> by Magdalena Małachowicz, Andrzej K. Siwicki, Stefan Dobosz, Roman Wenne

“…Between these were many genes involved in immune response, including lysozymes, pattern recognition receptors (c-type lectins), antimicrobial peptides (cathelicidin and hepcidin), acute-phase proteins (serum amyloids and haptoglobin), complement cascade proteins (<i>c3</i>, <i>c4</i>, <i>c6</i> and <i>c7</i>), interleukins (<i>il11</i> and <i>il1b</i>) and chemokines (<i>ccl19</i> and <i>cxcl8</i>). …”
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Immunological, Biochemical and Growth Performance Studies on Nile Tilapia Supplemented with Probiotic, Green Tea and Clove Oil by Ahmed Mohamed Ammar, Sarah Y.A. Abd El-Galil, Bassant Elsayed Mohamed, Amany Abd El-Aziz Gharib

“…While specific immunological measures like IgM and CRP show a large increase in groups treated with green tea, rather than clove oil, nonspecific immune data showed that the overall leukocytic count of the groups did not differ from one another. lysozymes were higher in the probiotics-treated group, although in comparison to other treated groups, the control group had higher levels of IgG. …”
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Immunoprotective Effect of <i>Coptis chinensis</i>-Supplemented Diet on <i>Streptococcus agalactiae</i> Infection in Tilapia by Ruijie Guo, Kai Yu, Kai Huang, Qiang Lin, Ting Liu

“…The specific upregulated proteins included important antimicrobial enzymes such as lysozymes and cathepsin D, and antimicrobial peptides such as septins, granulin, and grancalcin, involving multiple KEGG brite categories such as enzymes, exosomes, membrane transport, and proteolipid proteins. …”
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