Double-Fermented Soybean Meal Totally Replaces Soybean Meal in Broiler Rations with Favorable Impact on Performance, Digestibility, Amino Acids Transporters and Meat Nutritional Va... by Sherief M. Abdel-Raheem, El Said Yehia Mohammed, Rania Elsaid Mahmoud, Mahmoud Fathy El Gamal, Hend S. Nada, Waleed Rizk El-Ghareeb, Mohamed Marzok, Ahmed M. A. Meligy, Mohamad Abdulmohsen, Hesham Ismail, Doaa Ibrahim, Asmaa T. Y. Kishawy

“…In addition, higher inclusion levels of DFSBM increased blood immune response (IgG, IgM, nitric oxide and lysozyme levels) and liver antioxidant status. Jejunal amino acids- and peptide transporter-encoding genes (LAT1, CAT-1, CAT-2, PepT-1 and PepT-2) were upregulated with increasing levels of DFSBM in the ration. …”
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Protective effects of berberine in chronic copper-induced liver and gill injury in freshwater grouper (Acrossocheilus fasciatus) by Chenyang Wang, Lei Wang, Leqi Yang, Chang Gao, Bin Wang, Yilin Shu, Heng Wang, Yunzhi Yan

“…Berberine inclusion significantly decreased the activities of lysozyme and acid phosphatase, as well as the content of immunoglobulin M compared to the Cu group (P < 0.05). …”
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Nano-Curcumin/Chitosan Modulates Growth, Biochemical, Immune, and Antioxidative Profiles, and the Expression of Related Genes in <i>Nile tilapia</i>, <i>Oreochromis niloticus</i> by Hiam Elabd, Heba H. Mahboub, Shimaa M. R. Salem, Abdelwahab M. Abdelwahab, Khairiah Mubarak Alwutayd, Mohamed Shaalan, Sameh H. Ismail, Abdelfattah M. Abdelfattah, A. Khalid, Abdallah Tageldein Mansour, Heba S. Hamed, Hadeer Youssuf

“…Digestive enzyme (amylase), immune response markers (immunoglobulin M, nitrous oxide, and lysozyme activity), plasma albumin, and total protein were increased significantly, mainly with a diet supplemented with 0.00625 g NCur/kg. …”
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Influences of ferulic acid on intestinal digestive and antioxidant enzymes, immune, antioxidant gene and tight junction protein expression and microbiota in hybrid grouper (Epineph... by Weijie Fu, Eric Amenyogbe, Jun Luo, Erjun Yang, Jian-sheng Huang, Youming Chen, Gang Chen

“…The results showed that dietary 80–160 mg kg−1 FA intake considerably augmented the enzymes activities of digestion (lipase, trypsin, amylase, and pepsin) and antioxidation (superoxide dismutase, glutathione peroxidase, and catalase) and the values of immune parameters (Immunoglobulin, C3 and lysozyme), as well as reduced malondialdehyde content, with respect to the control group (P < 0.05). …”
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Advancing homogeneous networking principles for the development of fatigue-resistant, low-swelling and sprayable hydrogels for sealing wet, dynamic and concealed wounds in vivo by Yi Zhang, Yanjun Pan, Ronghang Chang, Kangli Chen, Kun Wang, Haoqi Tan, Meng Yin, Changsheng Liu, Xue Qu

“…This network is formed by combining the spherical structure of lysozyme (LZM) with the orthotetrahedral structure of 4-arm-polyethylene glycol (4-arm-PEG). …”
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Effects of Dietary <i>Saccharomyces cerevisiae</i> YFI-SC2 on the Growth Performance, Intestinal Morphology, Immune Parameters, Intestinal Microbiota, and Disease Resistance of Cra... by Yan Xu, Yiqun Li, Mingyang Xue, Tao Yang, Xiaowen Luo, Yuding Fan, Yan Meng, Wenzhi Liu, Ge Lin, Bo Li, Lingbing Zeng, Yong Zhou

“…For immune-related genes, Crustin2 expression was similar between the groups, whereas Lysozyme and prophenoloxidase from treatment group expression levels were upregulated significantly (<i>p</i> < 0.05) after 14 and 28 days of feeding. …”
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FABP4 in Paneth cells regulates antimicrobial protein expression to reprogram gut microbiota by Xiaomin Su, Mengli Jin, Chen Xu, Yunhuan Gao, Yazheng Yang, Houbao Qi, Qianjing Zhang, Xiaorong Yang, Wang Ya, Yuan Zhang, Rongcun Yang

“…T: Salmonella Typhimurium; HFD: High-fat diet; Defa: α-defensin; 930 HD5: Human α-defensin 5; HD6: Human α-defensin 6; F/B: Firmicutes/Bacteroidetes; SFB: Segmental filamentous bacteria; AMPs: Antimicrobial peptides; PPARγ: Peroxisome proliferator-activated receptor γ; P-PPAR: Phosphorylated PPAR; Dhx15: DEAD-box helicase 15; 935 EGF: Epidermal growth factor; ENR: Noggin and R-spondin 1; CFU: Colony forming unit; Lyz1: Lysozyme 1; Saa1: Serum amyoid A 1; Pla2g2a: Phospholipase A2, group IIA; MMP-7: Matrix metalloproteinase; AU-PAGE: Acid-urea polyacrylamide gel electrophoresis; PA: Palmitic 940 acid; GPR40: G-protein-coupled receptor; GF: Germ-free; EGF: Epidermal growth factor; LP: Lamina propria; KO: Knock out; WT: Wild-type.…”
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Long-Term Feeding with Curcumin Affects the Growth, Antioxidant Capacity, Immune Status, Tissue Histoarchitecture, Immune Expression of Proinflammatory Cytokines, and Apoptosis Ind... by Shimaa A. Amer, Doaa A. El-Araby, Haitham Tartor, Mahmoud Farahat, Nehal I. A. Goda, Mohamed F. M. Farag, Esraa M. Fahmy, Aziza M. Hassan, Mohamed F. Abo El-Maati, Ali Osman

“…IL10 and IgM levels were increased in the CUR200 and CUR400 groups. Lysozyme activity was increased in the CUR200–400 groups. …”
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Pathology, Enzyme Activity and Immune Responses after <i>Cryptocaryon irritans</i> Infection of Golden Pompano <i>Trachinotus ovatus</i> (Linnaeus 1758) by Hua-Yang Guo, Wen-Fu Li, Ke-Cheng Zhu, Bao-Suo Liu, Nan Zhang, Bo Liu, Jing-Wen Yang, Dian-Chang Zhang

“…Moreover, the activities of four enzymes, that is, alkaline phosphatase (AKP), acid phosphatase (ACP), superoxide dismutase (SOD) and lysozyme (LZM), were significantly increased in different tissues after <i>C. irritans</i> infection. …”
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Integrated analysis of immune parameters, miRNA-mRNA interaction, and immune genes expression in the liver of rainbow trout following infectious hematopoietic necrosis virus infect... by Shenji Wu, Jinqiang Huang, Yongjuan Li, Mingquan Lei, Lu Zhao, Zhe Liu

“…The results revealed that alkaline phosphatase (AKP), alanine aminotransferase (ALT), catalase (CAT), and total superoxide dismutase (T-SOD) activities, and lysozyme (LZM) content showed significant peaks at 48 hpi, whereas malondialdehyde (MDA) content and aspartate aminotransferase (AST) activity decreased continuously during infection, and acid phosphatase (ACP) activity varied slightly. …”
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Potential Implications of Natural Antioxidants of Plant Origin on Oxidative Stability of Chicken Albumen during Storage: A Review by Uchechukwu Edna Obianwuna, Vivian U. Oleforuh-Okoleh, Jing Wang, Hai-Jun Zhang, Guang-Hai Qi, Kai Qiu, Shu-Geng Wu

“…High albumen pH acts as a catalyst for structural changes in albumen, including degradation of the β-ovomucin subunit and <i>O</i>-glycosidic bonds, collapse of the ovomucin-lysozyme complex, and decline in albumen protein–protein interactions. …”
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An Efficient Triplex TaqMan Quantitative PCR to Detect a Blackleg-Causing Lineage of <i>Pectobacterium brasiliense</i> in Potato Based on a Pangenome Analysis by Theo A. J. van der Lee, Marga P. E. van Gent-Pelzer, Eef M. Jonkheer, Balázs Brankovics, Ilse M. Houwers, Jan M. van der Wolf, Peter J. M. Bonants, Inge van Duivenbode, Robert A. M. Vreeburg, Mathijs Nas, Sandra Smit

“…In a genetically homogeneous clade comprising all BL-causing <i>P. brasiliense</i> strains, two genes only present in the BL-causing strains were identified, one encoding a predicted lysozyme inhibitor Lprl (LZI) and one encoding a putative Toll/interleukin-1 receptor (TIR) domain-containing protein. …”
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Effects of dietary pomegranate peel supplementation on growth performance and biochemical responses of common carp, Cyprinus carpio, to chronic crowding stress by Morteza Yousefi, Seyyed Morteza Hoseini, Evgeny Vladimirovich Kulikov, Nikolay Valerievich Babichev, Marina Vladimirovna Bolshakova, Marina Ivanovna Shopinskaya, Roman Vasilievich Rogov, Andrey Nikolaevich Zharov

“…Dietary PP significantly improved plasma lysozyme (PP5, PP10, and PP15) and complement (PP5 and PP10) activities and mitigated their decrease after the stress (the best effects in PP10), but was not beneficial in mitigating plasma total immunoglobulin decrease after the stress. …”
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SCAP deficiency facilitates obesity and insulin resistance through shifting adipose tissue macrophage polarization by Jae-Ho Lee, Sun Hee Lee, Eun-Ho Lee, Jeong-Yong Cho, Dae-Kyu Song, Young Jae Lee, Taeg Kyu Kwon, Byung-Chul Oh, Kae Won Cho, Timothy F. Osborne, Tae-Il Jeon, Seung-Soon Im

“…Methods: Macrophage-specific SCAP knockout (mKO) mice were generated through crossbreeding lysozyme 2-cre mice with SCAP floxed mice which were then fed HFHS for 12 weeks. …”
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Thermodynamic Evaluation of the Interactions between Anticancer Pt(II) Complexes and Model Proteins by Chiara Pelosi, Francesca Saitta, Caterina Zerino, Giovanni Canil, Tarita Biver, Alessandro Pratesi, Celia Duce, Dimitrios Fessas, Chiara Gabbiani, Maria Rosaria Tiné

“…In this work, we have analysed the binding of the Pt(II) complexes ([PtCl(4′-phenyl-2,2′:6′,2″-terpyridine)](CF₃SO₃) (<b>1</b>), [PtI(4′-phenyl-2,2′:6′,2″-terpyridine)](CF₃SO₃) (<b>2</b>) and [PtCl(1,3-di(2-pyridyl)benzene) (<b>3</b>)] with selected model proteins (hen egg-white lysozyme, HEWL, and ribonuclease A, RNase A). Platinum coordination compounds are intensively studied to develop improved anticancer agents. …”
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The gene expression profile of the glucocorticoid receptor 1 (gr1) but not gr2 is modulated in mucosal tissues of gilthead sea bream (Sparus aurata) exposed to acute air-exposure s... by Eva Vallejos-Vidal, Beatriz Sanz-Milián, Mariana Teles, Mariana Teles, Sebastián Reyes-Cerpa, Sebastián Reyes-Cerpa, Juan Miguel Mancera, Lluis Tort, Felipe E. Reyes-López, Felipe E. Reyes-López

“…In this study, we evaluated the kinetics of modulation of cortisol receptors expression (gr1, gr2, mr), and its similarity with the expression pattern of selected genes associated with stress (hsp70; enolase) and immune response (lysozyme; c3; il-1β; tnf-α; il-10; tgf-β1) in gilthead sea bream mucosal tissues (skin; gills; anterior gut). …”
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Anti-S-layer monoclonal antibodies impact Clostridioides difficile physiology by Lise Hunault, Emile Auria, Patrick England, Julien Deschamps, Romain Briandet, Vanessa Kremer, Bruno Iannascoli, Léo Vidal-Maison, Chunguang Guo, Lynn Macdonald, Séverine Péchiné, Cécile Denève-Larrazet, Bruno Dupuy, Guy Gorochov, Pierre Bruhns, Delphine Sterlin

“…Moreover, one anti-SlpA mAb impaired C. difficile growth and conferred sensitivity to lysozyme-induced lysis. The results of this study show that anti-S-layer antibody responses can be beneficial or harmful for the course of CDI and provide important insights for the development of adequate S-layer-targeting therapeutics.…”
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The growth-promoting and lipid-lowering effects of berberine are associated with the regulation of intestinal bacteria and bile acid profiles in yellow catfish (Pelteobagrus fulvid... by Lei Wang, Chang Gao, Leqi Yang, Chenyang Wang, Bin Wang, Heng Wang, Yilin Shu, Yunzhi Yan

“…The BBR400 group showed significant improvements in growth performance, hepatic antioxidant enzyme activities, intestinal lysozyme activity, cholic acid, ethylchenodeoxycholic acid, and hydroguinone carboxylic acid contents, along with significantly lower intestinal immunoglobulin M, complement 3, complement 4, serum total cholesterol (TCH), and triglyceride (TG) contents, compared to the control group (P < 0.05). …”
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Protein and viral partitioning in two-phase aqueous micellar systems by Kamei, Daniel Takashi, 1972-

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Polysulfone based poly(methyl methacrylate) dual layer hollow fiber membrane incorporated with activated carbon for uremic toxins removal by Zainol Abidin, Muhammad Nidzhom

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