Environmental risk factors and exposure to the zoonotic malaria parasite Plasmodium knowlesi across northern Sabah, Malaysia: a population-based cross-sectional survey ‌ Fornace, Kimberly M, Brock, Paddy M, Tommy R Abidin, Grignard, Lynn, Herman, Lou S, Chua, Tock Hing, Sylvia Daim, William, Timothy, Patterson, Catriona L E B, Hall, Tom, Grigg, Matthew J, Anstey, Nicholas M, Tetteh, Kevin K A, Cox, Jonathan, Drakeley, Chris J

Ստացեք ամբողջական տեքստը
Ստացեք ամբողջական տեքստը

Short tandem repeat polymorphism in the promoter region of cyclophilin 19B drives its transcriptional upregulation and contributes to drug resistance in the malaria parasite Plasmodium falciparum ‌ Kucharski, Michal, Wirjanata, Grennady, Nayak, Sourav, Boentoro, Josephine, Dziekan, Jerzy Michal, Assisi, Christina, van der Pluijm, Rob W., Miotto, Olivo, Mok, Sachel, Dondorp, Arjen M., Bozdech, Zbynek

“…Resistance of the human malaria parasites, Plasmodium falciparum, to artemisinins is now fully established in Southeast Asia and is gradually emerging in Sub-Saharan Africa. …”
Ստացեք ամբողջական տեքստը

The role of the 235 kDA protein multigene family (py235) of the malaria parasite Plasmodium yoelii in invasion and host cell selection, virulence and immune evasion ‌ Jayasree Kaveri Iyer

Ստացեք ամբողջական տեքստը

Plasmodium falciparum malaria parasite var gene expression is modified by host antibodies: longitudinal evidence from controlled infections of Kenyan adults with varying natural exposure ‌ Abdi, A, Hodgson, S, Muthui, M, Kivisi, C, Kamuyu, G, Kimani, D, Hoffman, S, Juma, E, Ogutu, B, Draper, S, Osier, F, Bejon, P, Marsh, K, Bull, P

CD4 T cell responses to a variant antigen of the malaria parasite Plasmodium falciparum, erythrocyte membrane protein-1, in individuals living in malaria-endemic areas. ‌ Allsopp, C, Sanni, L, Reubsaet, L, Ndungu, F, Newbold, C, Mwangi, T, Marsh, K, Langhorne, J

Short-term changes in anemia and malaria parasite prevalence in children under 5 years during one year of repeated cross-sectional surveys in rural Malawi ‌ Kabaghe, A, Chipeta, M, Terlouw, D, McCann, R, van Vugt, M, Grobusch, M, Takken, W, Phiri, K

Comparing drug regimens for clearance of malaria parasites in asymptomatic adults using PCR in Kilifi County, Kenya: an open-label randomised controlled clinical trial (MalPaC) ‌ Khaemba, EN, Ogwang, C, Kinyanjui, S, Muindi, JM, Koske, JK, Kimani, D, Ngoi, J, Mwacharo, J, Shangala, J, Njuguna, P, Mutinda, D, Nyatichi, E, Peshu, J, Mutinda, B, Ndungu, FM, Farnert, A, Bashraheil, MM, Bejon, P, Kapulu, MC

Controlled Human Malaria Infection in Semi-Immune Kenyan Adults (CHMI-SIKA): A study protocol to investigate in vivo Plasmodium falciparum malaria parasite growth in the context of pre-existing immunity ‌ Kapulu, MC, Njuguna, P, Hamaluba, MM, Chmi-Sika Study Team

“…Adults in malaria endemic areas may have substantial immunity provided by responses to the blood stages of malaria parasites, but field trials conducted on several blood-stage vaccines have not shown high levels of efficacy.  …”

The Armadillo repeat protein PF16 is essential for flagellar structure and function in Plasmodium male gametes. ‌ Straschil, U, Talman, A, Ferguson, D, Bunting, K, Xu, Z, Bailes, E, Sinden, R, Holder, A, Smith, E, Coates, J, Tewari, R

“…PF16 is the first ARM-repeat protein characterised in the malaria parasite genus Plasmodium and this study opens up a novel model for analysis of Plasmodium flagellar biology that may provide unique insights into an ancient organelle and suggest novel intervention strategies to control the malaria parasite.…”

Identification of a polymorphic Plasmodium vivax microsatellite marker. ‌ Gomez, J, McNamara, D, Bockarie, M, Baird, J, Carlton, J, Zimmerman, P

“…Microsatellite markers derived from simple sequence repeats have been useful in studying a number of human pathogens, including the human malaria parasite Plasmodium falciparum. Genetic markers for P. vivax would likewise help elucidate the genetics and population characteristics of this other important human malaria parasite. …”

Plasmodium chabaudi: rosetting in a rodent malaria model. ‌ Mackinnon, M, Walker, P, Rowe, J

“…Rosetting is a property of many malaria parasite species that has been linked to virulence in the major species infecting humans, Plasmodium falciparum. …”

The impact of urbanization and population density on childhood Plasmodium falciparum parasite prevalence rates in Africa ‌ Kabaria, C, Gilbert, M, Noor, A, Snow, R, Linard, C

“…</p><p> METHODS AND RESULTS: This study sought to discriminate an urbanization definition that is most relevant for malaria parasite mapping using individual level malaria infection data obtained from nationally representative household-based surveys. …”

Split dosing of artemisinins does not improve antimalarial therapeutic efficacy ‌ White, N, Watson, J, Ashley, E

“…It has been suggested recently, based on pharmacokinetic-pharmacodynamic modelling exercises, that twice daily dosing of artemisinins increases malaria parasite killing and so could "dramatically enhance and restore drug effectiveness" in artemisinin resistant P. falciparum malaria infections. …”

Stage-specific depletion of myosin A supports an essential role in motility of malarial ookinetes. ‌ Siden-Kiamos, I, Ganter, M, Kunze, A, Hliscs, M, Steinbüchel, M, Mendoza, J, Sinden, R, Louis, C, Matuschewski, K

“…Similar approaches should permit the analysis of gene function in the mosquito forms that are shared with the erythrocytic stages of the malaria parasite.…”

Structure of the Plasmodium falciparum heat shock protein 70-x substrate binding domain ‌ Schmidt, J, Vakonakis, I

“…The malaria parasite Plasmodium falciparum extensively modifies erythrocytes that it invades by exporting a large complement of proteins to the host cell. …”

Quantitative proteomics reveals new insights into erythrocyte invasion by Plasmodium falciparum ‌ Kuss, Claudia, Gan, Chee Sian, Gunalan, Karthigayan, Bozdech, Zbynek, Sze, Siu Kwan, Preiser, Peter Rainer

“…Differential expression of ligands in the human malaria parasite Plasmodium falciparum enables it to recognize different receptors on the erythrocyte surface thereby providing alternative invasion pathways. …”
Ստացեք ամբողջական տեքստը
Ստացեք ամբողջական տեքստը

The mechanisms of parasite clearance after antimalarial treatment of Plasmodium falciparum malaria. ‌ Chotivanich, K, Udomsangpetch, R, Dondorp, A, Williams, T, Angus, B, Simpson, J, Pukrittayakamee, S, Looareesuwan, S, Newbold, C, White, N

“…Studies were conducted to determine how malaria parasites are cleared from the blood after antimalarial treatment. …”

Paternal effect of the nuclear formin-like protein MISFIT on Plasmodium development in the mosquito vector. ‌ Bushell, E, Ecker, A, Schlegelmilch, T, Goulding, D, Dougan, G, Sinden, R, Christophides, G, Kafatos, F, Vlachou, D

“…Malaria parasites must undergo sexual and sporogonic development in mosquitoes before they can infect their vertebrate hosts. …”

Genome-wide discovery and verification of novel structured RNAs in Plasmodium falciparum. ‌ Mourier, T, Carret, C, Kyes, S, Christodoulou, Z, Gardner, P, Jeffares, D, Pinches, R, Barrell, B, Berriman, M, Griffiths-Jones, S, Ivens, A, Newbold, C, Pain, A

“…We undertook a genome-wide search for novel noncoding RNAs (ncRNA) in the malaria parasite Plasmodium falciparum. We used the RNAz program to predict structures in the noncoding regions of the P. falciparum 3D7 genome that were conserved with at least one of seven other Plasmodium spp. genome sequences. …”

Implementation Of Image Processing Technique In FPGA ‌ Ng, Soo Kheng

“…This project implements a 3X3 median filter system for the removal of noise from blood smear images for malaria parasite detection. The system is described using VHDL into three building blocks. …”
Ստացեք ամբողջական տեքստը