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A synthetic biology platform for malaria parasites based on orthogonal transcriptional control
Published 2024“…Furthermore, the evolution of drug resistance among malaria parasites threatens to continue this trend. However, our understanding of malaria parasite biology is held back by a lack of tools with which to study the function of their genes. …”
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Thesis -
83
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84
Effect of exposure to malaria parasites on IGFBP7 expression profile of endothelial cells
Published 2020“…This study shows that different endothelial cells react differently to different species of malaria parasites in the context of IGFBP7 secretion.…”
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Final Year Project (FYP) -
85
Mediator complex of the malaria parasite plasmodium falciparum associates with evolutionarily novel subunits
Published 2022“…The genome of the human malaria parasite Plasmodium falciparum has been predicted to encode several Mediator subunits. …”
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Journal Article -
86
Functional analysis of molecular mechanisms associated with invasion of erythrocytes by human malaria parasite.
Published 2011“…The main objective of this project is to explore methods of high throughput functional genomics to analyze molecular mechanisms associated with the invasion machinery by which the human malaria parasites Plasmodium falciparum invade its host erythrocytes. …”
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Research Report -
87
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DNA damage regulation and its role in drug-related phenotypes in the malaria parasites
Published 2018“…DNA of malaria parasites, Plasmodium falciparum, is subjected to extraordinary high levels of genotoxic insults during its complex life cycle within both the mosquito and human host. …”
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Journal Article -
89
Oxidative stress and protein damage responses mediate artemisinin resistance in malaria parasites
Published 2018Get full text
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Journal Article -
90
Human erythrocyte remodelling during Plasmodium falciparum malaria parasite growth and egress
Published 2013Get full text
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Journal Article -
91
Multiplication and growth inhibition activity assays for the zoonotic malaria parasite, Plasmodium knowlesi
Published 2020Journal article -
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Transmission of artemisinin-resistant malaria parasites to mosquitoes under antimalarial drug pressure
Published 2020Journal article -
94
Key gaps in the knowledge of Plasmodium vivax, a neglected human malaria parasite.
Published 2009Journal article -
95
Assembling a global database of malaria parasite prevalence for the Malaria Atlas Project
Published 2007“…Methods: The exhaustive searches and assembly process for a global database of malaria parasite prevalence as part of the Malaria Atlas Project (MAP) are described. …”
Journal article -
96
Sex and death: the effects of innate immune factors on the sexual reproduction of malaria parasites.
Published 2011“…Malaria parasites must undergo a round of sexual reproduction in the blood meal of a mosquito vector to be transmitted between hosts. …”
Journal article -
97
Geographical distribution of selected and putatively neutral SNPs in Southeast Asian malaria parasites.
Published 2005Journal article -
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Oxidative stress and protein damage responses mediate artemisinin resistance in malaria parasites
Published 2018Journal article -
99
A selective sweep driven by pyrimethamine treatment in southeast asian malaria parasites.
Published 2003“…Malaria parasites (Plasmodium falciparum) provide an excellent system in which to study the genomic effects of strong selection in a recombining eukaryote because the rapid spread of resistance to multiple drugs during the last the past 50 years has been well documented, the full genome sequence and a microsatellite map are now available, and haplotype data can be easily generated. …”
Journal article -
100
Deep Learning for Smartphone-Based Malaria Parasite Detection in Thick Blood Smears
Published 2019“…<br><strong>Objective: </strong>This work investigates the possibility of automated malaria parasite detection in thick blood smears with smartphones.…”
Journal article