First two fungemia cases caused by Candida haemulonii var. vulnera in China with emerged antifungal resistance by Xin-Fei Chen, Xin-Fei Chen, Xin-Fei Chen, Xin Hou, Han Zhang, Han Zhang, Xin-Miao Jia, Xin-Miao Jia, Li-Ping Ning, Wei Cao, Xin Fan, Jing-Jing Huang, Jing-Jing Huang, Jing-Jing Huang, Wen-Hang Yang, Wen-Hang Yang, Ge Zhang, Ge Zhang, Jing-Jia Zhang, Jing-Jia Zhang, Wei Kang, Wei Kang, Meng Xiao, Meng Xiao, Ying-Chun Xu, Ying-Chun Xu

“…The identification capacity of three matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) and VITEK 2 YST ID biochemical methods were evaluated against ITS sequencing. …”
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A Novel Strategy for the Detection of SARS-CoV-2 Variants Based on Multiplex PCR-Mass Spectrometry Minisequencing Technology by Fei Zhao, Jinxing Lu, Bing Lu, Tian Qin, Xuemei Wang, Xuexin Hou, Fanliang Meng, Xiaona Xu, Tianyi Li, Haijian Zhou, Jianzhong Zhang, Biao Kan, Ying Huang, Zehui Zhang, Di Xiao

“…Using the nucleic acid sequence of a SARS-CoV-2 nonvariant and a synthetic SARS-CoV-2 variant-carrying plasmid, a matrix-assisted laser desorption ionization–time of flight mass spectrometry (MALDI-TOF MS) method based on the single-base mass probe extension of multiplex PCR amplification products was established to detect 9 mutation types in 7 mutated sites (HV6970del, N501Y, K417N, P681H, D614G, E484K, L452R, E484Q, and P681R) in the receptor-binding domain of the spike protein of SARS-CoV-2 variants. …”
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Serum peptidomic screening identified circulating peptide biomarkers predictive for preeclampsia by Shenglong Zhao, Chenghong Yin, Yanhong Zhai, Yanhong Zhai, Zhaoxia Jia, Shaofei Su, Yifan Lu, Lanlan Meng, Chunbo Li, Xiang Liu, Yuting Cong, Youran Li, Youran Li, Ying Liu, Ying Liu, Lu Chen, Jing Wang, Zhengwen Xu, Yuanyuan Zheng, Zhi Sun, Zhi Sun, Ruben Y. Luo, Xiaobo Yu, He S. Yang, Xiaowei Liu, Zhen Zhao, Zheng Cao, Zheng Cao

“…Serum peptidomic analysis was performed in the discovery cohort of 115 samples using matrix-assisted laser desorption ionization-time of flight coupled with Linear Trap Quadropole Orbitrap mass spectrometry. …”
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The fatal trajectory of pulmonary COVID-19 is driven by lobular ischemia and fibrotic remodelling by Maximilian Ackermann, Jan C. Kamp, Christopher Werlein, Claire L. Walsh, Helge Stark, Verena Prade, Rambabu Surabattula, Willi L. Wagner, Catherine Disney, Andrew J. Bodey, Thomas Illig, Diana J. Leeming, Morten A. Karsdal, Alexandar Tzankov, Peter Boor, Mark P. Kühnel, Florian P. Länger, Stijn E. Verleden, Hans M. Kvasnicka, Hans H. Kreipe, Axel Haverich, Stephen M. Black, Axel Walch, Paul Tafforeau, Peter D. Lee, Marius M. Hoeper, Tobias Welte, Benjamin Seeliger, Sascha David, Detlef Schuppan, Steven J. Mentzer, Danny D. Jonigk

“…Methods: We studied a total of 85 lungs (n = 31 COVID autopsy samples; n = 7 influenza A autopsy samples; n = 18 interstitial lung disease explants; n = 24 healthy controls) using the highest resolution Synchrotron radiation-based hierarchical phase-contrast tomography, scanning electron microscopy of microvascular corrosion casts, immunohistochemistry, matrix-assisted laser desorption ionization mass spectrometry imaging, and analysis of mRNA expression and biological pathways. …”
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Antifungal susceptibility profiles and drug resistance mechanisms of clinical Candida duobushaemulonii isolates from China by Xin-Fei Chen, Xin-Fei Chen, Xin-Fei Chen, Han Zhang, Han Zhang, Xin-Miao Jia, Xin-Miao Jia, Jin Cao, Li Li, Xin-Lan Hu, Ning Li, Yu-Ling Xiao, Fei Xia, Li-Yan Ye, Qing-Feng Hu, Xiao-Li Wu, Li-Ping Ning, Po-Ren Hsueh, Po-Ren Hsueh, Xin Fan, Shu-Ying Yu, Shu-Ying Yu, Jing-Jing Huang, Jing-Jing Huang, Jing-Jing Huang, Xiu-Li Xie, Xiu-Li Xie, Wen-Hang Yang, Wen-Hang Yang, Wen-Hang Yang, Ying-Xing Li, Ying-Xing Li, Ge Zhang, Ge Zhang, Jing-Jia Zhang, Jing-Jia Zhang, Si-Meng Duan, Si-Meng Duan, Wei Kang, Wei Kang, Tong Wang, Tong Wang, Jin Li, Jin Li, Meng Xiao, Meng Xiao, Xin Hou, Ying-Chun Xu, Ying-Chun Xu

“…Eleven strains of C. duobushaemulonii were collected from China Hospital Invasive Fungal Surveillance Net (CHIF-NET) and identified using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF), VITEK 2 Yeast Identification Card (YST), and internal transcribed spacer (ITS) sequencing. …”
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Mapping the Lipids of Skin Sebaceous Glands and Hair Follicles by High Spatial Resolution MALDI Imaging Mass Spectrometry by Fang Xie, Mark Reid Groseclose, Sara Tortorella, Gabriele Cruciani, Stephen Castellino

“…Matrix-assisted laser desorption/ionization (MALDI) imaging mass spectrometry (IMS) is a technology that utilizes the high sensitivity and specificity of mass spectrometry, combined with a high spatial resolution to characterize the molecular species present in skin tissue. …”
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MALDI-TOF: A new tool for the identification of Schistosoma cercariae and detection of hybrids. by Antoine Huguenin, Julien Kincaid-Smith, Jérôme Depaquit, Jérôme Boissier, Hubert Ferté

“…Our objective was to assess the performance of MALDI-TOF (Matrix Assistated Laser Desorption-Ionization-Time Of Flight) mass spectrometry for the specific identification of cercariae in human and non-human Schistosoma and for the detection of hybridization between S. bovis and S. haematobium. …”
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