Showing 201 - 220 results of 41,866 for search '"mechanistic"', query time: 0.22s Refine Results
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    Mechanistic Insights of Ethylene Polymerization on Phillips Chromium Catalysts by Ilya Nifant’ev, Pavel Komarov, Guzelia Sadrtdinova, Vadim Safronov, Nikolay Kolosov, Pavel Ivchenko

    Published 2024-03-01
    “…On the other hand, conflicting experimental data continue to be obtained, and certain mechanistic concepts are being developed with the use of outdated models. …”
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    Therapeutic and Mechanistic Perspectives of Protein Complexes in Breast Cancer by Mark P. Waterhouse, Rosie Ugur, Walid T. Khaled

    Published 2019-12-01
    “…Here, we will argue that more research is needed to identify the protein-protein interactions of TNBC oncogenes as a means for (a) mechanistically understanding the biological function of these oncogenes in TNBC and (b) providing novel therapeutic targets that can be exploited for selectively inhibiting the oncogenic roles of TNBC oncogenes in cancer cells, whilst sparing normal healthy cells.…”
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    A mechanistic view of mitochondrial death decision pores by J.E. Belizário, J. Alves, J.M. Occhiucci, M. Garay-Malpartida, A. Sesso

    Published 2007-08-01
    “…In this review, we discuss the mechanistic models by which reactive oxygen species and caspases, via structural and conformational changes of membrane lipids and proteins, promote conditions for inner/outer membrane permeabilization, which may be followed by either opening of pores or a rupture of the outer mitochondrial membrane.…”
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    Mechanistically distinct mouse models for CRX-associated retinopathy. by Nicholas M Tran, Alan Zhang, Xiaodong Zhang, Julie B Huecker, Anne K Hennig, Shiming Chen

    Published 2014-02-01
    “…E168d2 and R90W are mechanistically distinct mouse models for CRX-associated disease that will allow the elucidation of molecular mechanisms and testing of novel therapeutic approaches for different forms of CRX-associated disease.…”
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    Mechanistic Study of the Spiroindolones: A New Class of Antimalarials by Thomas H. Keller, Bryan K. S. Yeung, Louis-Sebastian Sonntag, Seh Yong Leong, Peiling Yap, Bin Zou

    Published 2012-08-01
    “…By isolating both the <strong>4<em>E</em></strong> and <strong>4<em>Z</em></strong> imine intermediates, a systematic mechanistic study of the reaction under both kinetic and thermodynamic conditions was conducted. …”
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    Mechanistic Insights into the Antibiofilm Mode of Action of Ellagic Acid by Alessandro Ratti, Enrico M. A. Fassi, Fabio Forlani, Matteo Mori, Federica Villa, Francesca Cappitelli, Jacopo Sgrignani, Gabriella Roda, Andrea Cavalli, Stefania Villa, Giovanni Grazioso

    Published 2023-06-01
    “…This work aims to provide mechanistic insights into the antibiofilm mode of action of EA utilizing computational studies, biophysical measurements, enzyme inhibition studies on WrbA, and biofilm and reactive oxygen species assays exploiting a WrbA-deprived mutant strain of <i>Escherichia coli</i>. …”
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    The Cycloaddition of the Benzimidazolium Ylides with Alkynes: New Mechanistic Insights. by Costel Moldoveanu, Gheorghita Zbancioc, Dorina Mantu, Dan Maftei, Ionel Mangalagiu

    Published 2016-01-01
    “…The proposed pathway leading both to 2-(1H-pyrrol-1-yl)anilines and to pyrrolo[1,2-a]quinoxalin-4(5H)-ones involves an opening of the imidazole ring from the cycloaddition product, followed by a nucleophilic attack of the aminic nitrogen to a proximal carbonyl group and the elimination of a leaving group. The mechanistic considerations are fully supported by experimental data, including the XRD resolved structure of the key reaction intermediate.…”
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