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  1. 221

    Bridging Mechanistic and Phenomenological Models of Complex Biological Systems. by Mark K Transtrum, Peng Qiu

    Published 2016-05-01
    “…The inherent complexity of biological systems gives rise to complicated mechanistic models with a large number of parameters. …”
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    Turix, a dynamic mechanistic model for feed evaluation by Luis Manuel Vargas-Villamil, Juan Carlos Ku-Vera, Felipe Vargas-Villamil, Salvador Medina-Peralta, Eric José Avila-Vales, Emilio Manuel Aranda-Ibañez, Leonel Avendaño-Reyes

    Published 2013-04-01
    “…The objective of this study was to use the Turix model (a new mechanistic dynamic model that can be used for feed evaluation under tropical conditions), along with in situ and in vitro sugar cane experimental data from a previous study, to evaluate sugar cane kinetics through estimation of three parameters associated with ruminal bacterial growth: kM,SmL, the substrate uptake; kLM, the bacterial growth from intermediate metabolite; and Y VFAP,FS, the products related to volatile fatty acid yield. …”
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    Mechanistic Insights on Hyperthermic Intraperitoneal Chemotherapy in Ovarian Cancer by Olivia G. Huffman, Danielle B. Chau, Andreea I. Dinicu, Robert DeBernardo, Ofer Reizes

    Published 2023-02-01
    “…The present review aims to provide insight into the mechanistic benefit of HIPEC treatment with a focus on how hyperthermia activates the immune response, induces DNA damage, impairs DNA damage repair pathways, and has a synergistic effect with chemotherapy, with the ultimate outcome of increasing chemosensitivity. …”
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    Mechanistic Aspects for the Modulation of Enzyme Reactions on the DNA Scaffold by Peng Lin, Hui Yang, Eiji Nakata, Takashi Morii

    Published 2022-09-01
    “…This review highlights the mechanistic aspects for the modulation of enzymatic reactions on the DNA scaffold.…”
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    Structure and mechanistic features of the prokaryotic minimal RNase P by Rebecca Feyh, Nadine B Waeber, Simone Prinz, Pietro Ivan Giammarinaro, Gert Bange, Georg Hochberg, Roland K Hartmann, Florian Altegoer

    Published 2021-06-01
    “…Our analysis thus delivers the structural and mechanistic basis for pre-tRNA processing by the prokaryotic HARP system.…”
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    Mechanistic decomposition and reduction in complex, context-sensitive systems by Daniel C. Burnston

    Published 2022-11-01
    “…Standard arguments in philosophy of science infer from the complexity of biological and neural systems to the presence of emergence and failure of mechanistic/reductionist explanation for those systems. …”
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    Key Mechanistic Principles and Considerations Concerning RNA Interference by Petr Svoboda

    Published 2020-08-01
    “…The aim of this text is to provide an introductory overview of key mechanistic aspects of RNA interference for understanding its potential and constraints for its use in pest control.…”
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