Showing 101 - 120 results of 41,866 for search '"mechanistic"', query time: 0.32s Refine Results
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    Metabolic diseases and pro- and prebiotics: Mechanistic insights by Nakamura Yukiko K, Omaye Stanley T

    Published 2012-06-01
    “…This review focuses on mechanistic links between metabolic diseases (mainly obesity and type 2 diabetes), chronic systemic low-grade inflammation, intestinal environment, and nutrition and prospective views of probiotic and prebiotic interventions for the diseases.…”
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  7. 107

    The Mechanistic Differences in HLA-Associated Carbamazepine Hypersensitivity by Gwendolin S. Simper, Lareen S. Gräser, Alexander A. Celik, Joachim Kuhn, Heike Kunze-Schumacher, Gia-Gia T. Hò, Rainer Blasczyk, Andreas Pich, Christina Bade-Doeding

    Published 2019-10-01
    “…Together with observed changes in the proteome elicited through carbamazepine or its metabolite these results illustrate the mechanistic differences in carbamazepine hypersensitivity for HLA-A*31:01 or B*15:02 patients and constitute the bridge between pharmacology and pharmacogenetics for personalized therapeutics.…”
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    The Functional and Mechanistic Roles of Immunoproteasome Subunits in Cancer by Satyendra Chandra Tripathi, Disha Vedpathak, Edwin Justin Ostrin

    Published 2021-12-01
    “…While accelerated proteasomal degradation is an important tumorigenic mechanism deployed by several cancers, there is some ambiguity regarding the role of immunoproteasome induction in neoplastic transformation. Understanding the mechanistic and functional relevance of the immunoproteasome provides essential insights into developing targeted therapies, including overcoming resistance to standard proteasome inhibition and immunomodulation of the tumor microenvironment. …”
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  10. 110

    A Mechanistic Model for Long COVID Dynamics by Jacob Derrick, Ben Patterson, Jie Bai, Jin Wang

    Published 2023-11-01
    “…In this paper, we propose a new mechanistic model based on differential equations to investigate the population dynamics of long COVID. …”
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    The Mechanistic Integration and Thermodynamic Optimality of a Nanomotor by Ruizheng Hou

    Published 2022-02-01
    “…The performance of artificial nanomotors is still far behind nature-made biomolecular motors. A mechanistic disparity between the two categories exists: artificial motors often rely on a single mechanism to rectify directional motion, but biomotors integrate multiple mechanisms for better performance. …”
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    Mechanistic Formulation Design of Spray-Dried Powders by Mani Ordoubadi, Hui Wang, Reinhard Vehring

    Published 2022-07-01
    “…Formulation design based on a mechanistic understanding of the different phenomena that occur during the spray drying of powders is complicated and can therefore make the use of available particle formation models difficult for the practitioner. …”
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    Mechanistic advances in osteoporosis and anti‐osteoporosis therapies by Haiwei Wang, Yuchuan Luo, Haisheng Wang, Feifei Li, Fanyuan Yu, Ling Ye

    Published 2023-06-01
    “…In this study, we systematically reviewed literatures and clinical evidences to both mechanistically and clinically demonstrate the state‐of‐art advances in osteoporosis. …”
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