Mechanistic insights into the rational design of masked antibodies by Carolina T. Orozco, Manuela Bersellini, Lorraine M. Irving, Wesley W. Howard, David Hargreaves, Paul W. A. Devine, Elise Siouve, Gareth J. Browne, Nicholas J. Bond, Jonathan J. Phillips, Peter Ravn, Sophie E. Jackson

“…Here, we undertook mechanistic studies using three masks with different properties and identified four critical factors: binding site and affinity, as well as association and dissociation rate constants, which also played an important role. …”
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Clarifying the relation between mechanistic explanations and reductionism by Mark Couch

Subjects: “…mechanistic explanation…”
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Melatonin in Endometriosis: Mechanistic Understanding and Clinical Insight by Yiran Li, Sze-Wan Hung, Ruizhe Zhang, Gene Chi-Wai Man, Tao Zhang, Jacqueline Pui-Wah Chung, Lanlan Fang, Chi-Chiu Wang

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Mechanistic Studies of Idiosyncratic DILI: Clinical Implications by Jack Uetrecht

“…The idiosyncratic nature of idiosyncratic drug-induced liver injury (IDILI) makes mechanistic studies very difficult, and little is known with certainty. …”
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The Mechanistic Roles of Sirtuins in Breast and Prostate Cancer by Cosmos Ifeanyi Onyiba, Christopher J. Scarlett, Judith Weidenhofer

“…In this review, we discuss the current information on the mechanistic roles of SIRT1–7 and their downstream effects (tumor promotion or suppression) in cancers of the breast and prostate. …”
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Mechanistic causes of sign epistasis and its applications by Jinqiu Zhang, Feiyu Chen, Feiyu Chen, Xianghua Li, Xianghua Li, Xianghua Li

“…Despite its importance, there is a limited systematic overview of the mechanistic causes of sign epistasis. This review explores the mechanistic causes, highlighting its occurrence in signalling cascades, peaked fitness landscapes, and physical interactions. …”
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Mechanistic action of weak acid drugs on biofilms by Kundukad, Binu, Yang, Kaiyuan, Seviour, Thomas, Yang, Liang, Rice, Scott A., Kjelleberg, Staffan, Schussman, Megan K., Doyle, Patrick S

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Mechanistic modeling of bacterial nutrient uptake strategies by Norris, Noele Rosalie.

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Mechanistic insights into the origin of the oxygen migration barrier by Vivona, Daniele, Gordiz, Kiarash, Meyer, Randall, Raman, Sumathy, Shao-Horn, Yang

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Synthetic and mechanistic study of catalytic dintrogen reduction by Weare, Walter Warren

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Mechanistic studies on chemical instabilities of recombinant proteins by Pan, Bin, Ph. D. Massachusetts Institute of Technology

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Intersystem crossing in acetylene : a mechanistic study by Altunata, Selen, 1973-

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The Genetic and Mechanistic Basis for Variation in Gene Regulation by Pai, Athma A., Pritchard, Jonathan K., Gilad, Yoav

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Unraveling the mechanistic origins of epoxy degradation in acids by Lim, Jacob Song Kiat, Gan, Chee Lip, Hu, Matthew Xiao

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Mechanistic insights in the autonomic modulation of ventricular arrhythmia by Kalla, M

“…This leads to the specific aims of the thesis which were to determine the mechanisms of the cholinergic antifibrillatory effect, investigate the role of cotransmission in arrhythmogenesis and, the mechanistic role of BH4 in autonomic cardiovascular control. …”

Mechanistic roles of protein disorder within transcription by Shammas, S

Mechanistic studies on histone demethylases and related enzymes by Hopkinson, RJ

Structural and mechanistic studies on γ-butyrobetaine hydroxylase. by Leung, I, Krojer, T, Kochan, G, Henry, L, von Delft, F, Claridge, T, Oppermann, U, McDonough, M, Schofield, C

“…We report structural and mechanistic studies on BBOX and its reaction with THP. …”

Kinetic and mechanistic study of the methane coupling reaction by Burch, R, Tsang, S, Swarnakar, R

Structural and mechanistic studies of porcine pancreatic elastase by Linyard, JDS