Nucleosome reorganisation in breast cancer tissues by Divya R. Jacob, Wilfried M. Guiblet, Hulkar Mamayusupova, Mariya Shtumpf, Isabella Ciuta, Luminita Ruje, Svetlana Gretton, Milena Bikova, Clark Correa, Emily Dellow, Shivam P. Agrawal, Navid Shafiei, Anastasija Drobysevskaja, Chris M. Armstrong, Jonathan D. G. Lam, Yevhen Vainshtein, Christopher T. Clarkson, Graeme J. Thorn, Kai Sohn, Madapura M. Pradeepa, Sankaran Chandrasekharan, Greg N. Brooke, Elena Klenova, Victor B. Zhurkin, Vladimir B. Teif

“…It is also important for medical diagnostics based on cell-free DNA (cfDNA), which originates from genomic DNA regions protected from digestion by nucleosomes. …”
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ROS-responsive liposomes as an inhaled drug delivery nanoplatform for idiopathic pulmonary fibrosis treatment via Nrf2 signaling by Junzhao Liu, Zuohong Wu, Yadong Liu, Zhu Zhan, Liping Yang, Can Wang, Qinqin Jiang, Haitao Ran, Pan Li, Zhigang Wang

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Profiling vitamin D, its mediators and proinflammatory cytokines in rheumatoid arthritis: A case–control study by Samuel A. Sakyi, Mavis Owusu‐Yeboah, Christian Obirikorang, Richard K. Dadzie Ephraim, Alexander Kwarteng, Stephen Opoku, Bright O. Afranie, Ebenezer Senu, Andy O. Boateng, Derrick K. Boakye, Tonnies A. Buckman, Benjamin Amoani

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Does the Automatic Measurement of Interleukin 6 Allow for Prediction of Complications during the First 48 h of Acute Pancreatitis? by Witold Kolber, Paulina Dumnicka, Małgorzata Maraj, Beata Kuśnierz-Cabala, Piotr Ceranowicz, Michał Pędziwiatr, Barbara Maziarz, Małgorzata Mazur-Laskowska, Marek Kuźniewski, Mateusz Sporek, Jerzy Walocha

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Safety of COVID-19 vaccination in women undergoing IVF/ICSI treatment - Clinical study and systematic review by Huijun Chen, Huijun Chen, Xiaoli Zhang, Xiaoli Zhang, Ge Lin, Ge Lin, Ge Lin, Fei Gong, Fei Gong, Fei Gong, Berthold Hocher, Berthold Hocher, Berthold Hocher

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Detection of S-HBsAg Mutations in Patients with Hematologic Malignancies by Maria V. Konopleva, Maxim S. Belenikin, Andrei V. Shanko, Alexey I. Bazhenov, Sergei A. Kiryanov, Tatyana A. Tupoleva, Maria V. Sokolova, Alexander V. Pronin, Tatyana A. Semenenko, Anatoly P. Suslov

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Whether Detection of Gene Mutations Could Identify Low- or High-Risk Papillary Thyroid Microcarcinoma? Data from 393 Cases Using the Next-Generation Sequencing by Lei Jin, Liang Zhou, Jian-Biao Wang, Li Tao, Xiao-Xiao Lu, Na Yan, Qian-Ming Chen, Li-Ping Cao, Lei Xie

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Nanopore-based metagenomics analysis reveals microbial presence in amniotic fluid: A prospective study by Lihang Zhong, Yunjun Yan, Long Chen, Na Sun, Hongyan Li, Yuli Wang, Huijun Liu, Yifang Jia, Yurong Lu, Xuling Liu, Yu Zhang, Huimin Guo, Xietong Wang

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Size‐Controlled DNA Tile Self‐Assembly Nanostructures Through Caveolae‐Mediated Endocytosis for Signal‐Amplified Imaging of MicroRNAs in Living Cells by Yanan Peng, Zhijun Gao, Bin Qiao, Dongxia Li, Huajie Pang, Xiangde Lai, Qiumei Pu, Rui Zhang, Xuan Zhao, Guangyuan Zhao, Dan Xu, Yuanyuan Wang, Yuxiang Ji, Hua Pei, Qiang Wu

“…This strategy provides a high‐potential delivery pathway for cell imaging and targeted delivery, simultaneously offering a meaningful reference for the application of DNA tile self‐assembly technology in relevant fundamental research and medical diagnostics.…”
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Resolvin D1 Attenuates Inflammation and Pelvic Pain Associated with EAP by Inhibiting Oxidative Stress and NLRP3 Inflammasome Activation via the Nrf2/HO-1 Pathway by Zhang J, Chen J, Jiang Q, Feng R, Zhao X, Li H, Yang C, Hua X

“…Jiong Zhang,1,2,* Juan Chen,3,* Qing Jiang,1,* Rui Feng,2 Xiaohu Zhao,2 Haolin Li,2 Cheng Yang,2 Xiaoliang Hua1 1Department of Urology, the Second Affiliated Hospital of Chongqing Medical University, Chongqing, People’s Republic of China; 2Department of Urology, the First Affiliated Hospital of Anhui Medical University, Hefei, People’s Republic of China; 3The Ministry of Education Key Laboratory of Laboratory Medical Diagnostics, the College of Laboratory Medicine, Chongqing Medical University, Chongqing, 400016, People’s Republic of China*These authors contributed equally to this workCorrespondence: Cheng Yang, Department of Urology, the First Affiliated Hospital of Anhui Medical University, No. 218 Jixi Road, Shushan District, Hefei, 230022, People’s Republic of China, Tel +86 0551 6292 3440, Fax +86 551 6363 3742, Email chengyang_md@163.com Xiaoliang Hua, Department of Urology, the Second Affiliated Hospital of Chongqing Medical University, No. 74 Linjiang Road, Yuzhong District, Chongqing, 400010, People’s Republic of China, Tel\Fax +86 023 6369 3222, Email hua_xiaoliang@cqmu.edu.cnBackground: Resolvin D1 (RvD1), a member of the specialized pro-resolving lipid mediators family, has a potent anti-inflammatory effect and alleviates tissue damage. …”
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Application and Uses of Electronic Noses for Clinical Diagnosis on Urine Samples: A Review by Laura Capelli, Gianluigi Taverna, Alessia Bellini, Lidia Eusebio, Niccolò Buffi, Massimo Lazzeri, Giorgio Guazzoni, Giorgio Bozzini, Mauro Seveso, Alberto Mandressi, Lorenzo Tidu, Fabio Grizzi, Paolo Sardella, Giuseppe Latorre, Rodolfo Hurle, Giovanni Lughezzani, Paolo Casale, Sara Meregali, Selena Sironi

“…This paper focuses on the review of electronic nose studies and applications in the specific field of medical diagnostics based on the analysis of the gaseous headspace of human urine, in order to provide a broad overview of the state of the art and thus enhance future developments in this field. …”
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Elevated circulating GPHB5 levels in women with insulin resistance and polycystic ovary syndrome: A cross-sectional study and multiple intervention studies by Yanping Wang, Yanping Wang, Ting Xiang, Xuyun Xia, Hongmin Zhang, Shan Geng, Gangyi Yang, Sheng Qiu, Yirui He, Rui Liu, Ling Li, Hua Liu, Ke Li, Lili Zhang, Zerong Liang, Jianguo He

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Case report: A case of severe acute hepatitis of unknown origin by Yu-Jiao Zhou, Hui-Ying Gu, Qi-Qin Tang, Fan Li, Jin Zhu, Ting Ai, Kun Zhu, Bin-Yue Xu, Qing Wang, Ai-Long Huang, Juan Chen, Juan Chen, Zhen-Zhen Zhang

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Recent Insights and Multifactorial Applications of Carbon Nanotubes by Muthu Thiruvengadam, Govindasamy Rajakumar, Venkata Swetha, Mohammad Azam Ansari, Saad Alghamdi, Mazen Almehmadi, Mustafa Halawi, Lakshmanan Kungumadevi, Vaishnavi Raja, Sulthana Sabura Sarbudeen, Saranya Madhavan, Maksim Rebezov, Mohammad Ali Shariati, Alexandr Sviderskiy, Konstantin Bogonosov

“…This review discusses the characteristics of carbon nanotubes as well as therapeutic applications such as medical diagnostics and drug delivery.…”
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The Activation of M1 Macrophages is Associated with the JNK-m6A-p38 Axis in Chronic Obstructive Pulmonary Disease by Hu T, Pang N, Li Z, Xu D, Jing J, Li F, Ding J, Wang J, Jiang M

“…Tingting Hu,1,* Nannan Pang,2,* Zheng Li,1 Dan Xu,1 Jing Jing,1 Fengsen Li,1 Jianbing Ding,3 Jing Wang,1 Min Jiang1 1Xinjiang Laboratory of Respiratory Disease Research, Traditional Chinese Medicine Hospital Affiliated to Xinjiang Medical University, Urumqi, 830000, People’s Republic of China; 2CAS Key Laboratory of Bio-Medical Diagnostics, Suzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Sciences, Suzhou, 215163, People’s Republic of China; 3Department of Immunology, College of Basic Medicine, Xinjiang Medical University, Urumqi, 830000, People’s Republic of China*These authors contributed equally to this workCorrespondence: Jing Wang; Min Jiang, Xinjiang Laboratory of Respiratory Disease Research, Traditional Chinese Medicine Hospital Affiliated to Xinjiang Medical University, Urumqi, People’s Republic of China, Tel +86-13999908413 ; +86-13999162873, Email jingw_xj@163.com; 250579087@qq.comBackground: Excessive activation of M1 macrophages affects the chronic inflammatory response of the airways and leads to the development of chronic obstructive pulmonary disease (COPD). …”
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DNMT3A R882H mutation drives daunorubicin resistance in acute myeloid leukemia via regulating NRF2/NQO1 pathway by Xuan Chu, Liang Zhong, Wenran Dan, Xiao Wang, Zhonghui Zhang, Zhenyan Liu, Yang Lu, Xin Shao, Ziwei Zhou, Shuyu Chen, Beizhong Liu

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Attention to Monkeypox: An Interpretable Monkeypox Detection Technique Using Attention Mechanism by Avi Deb Raha, Mrityunjoy Gain, Rameswar Debnath, Apurba Adhikary, Yu Qiao, Md. Mehedi Hassan, Anupam Kumar Bairagi, Sheikh Mohammed Shariful Islam

“…The limitation of these models often involves a trade-off with accuracy, which is unacceptable in the context of medical diagnostics. Therefore, the development of optimized deep learning models that are both resource-efficient for edge computing and highly accurate becomes imperative. …”
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Halogenated Thermally Activated Delayed Fluorescence Materials for Efficient Scintillation by Xiao Wang, Guowei Niu, Zixing Zhou, Zhicheng Song, Ke Qin, Xiaokang Yao, Zhijian Yang, Xiaoze Wang, He Wang, Zhuang Liu, Chengzhu Yin, Huili Ma, Kang Shen, Huifang Shi, Jun Yin, Qiushui Chen, Zhongfu An, Wei Huang

“…Here, we employ halogenated thermally activated delayed fluorescence materials to improve the triplet exciton utilization and X-ray absorption simultaneously, generating efficient scintillation with a low detection limit, which is one order of magnitude lower than the dosage for X-ray medical diagnostics. Through experimental study and theoretical calculation, we reveal the positive role of X-ray absorption, quantum yields of prompt fluorescence, and intersystem crossing in promoting the radioluminescence intensity. …”
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Using Human‐Induced Pluripotent Stem Cell Derived Neurons on Microelectrode Arrays to Model Neurological Disease: A Review by Shiya Lv, Enhui He, Jinping Luo, Yaoyao Liu, Wei Liang, Shihong Xu, Kui Zhang, Yan Yang, Mixia Wang, Yilin Song, Yirong Wu, Xinxia Cai

“…Finally, the future development and outlook of multifunctional and integrated devices for in vitro medical diagnostics and treatment are discussed.…”
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Characteristics of Serum Autoantibody Repertoire and Immune Subgroup Variation of Tuberculosis-Associated Obstructive Pulmonary Disease by Jiang M, Pang N, Wang J, Li Z, Xu D, Jing J, Chen D, Li F, Ding J, Li Q

“…Min Jiang,1,* NanNan Pang,2,* Jing Wang,1 Zheng Li,1 Dan Xu,1 Jing Jing,1 Dan Chen,3 Fengsen Li,1 Jianbing Ding,4 Qifeng Li5 1Xinjiang Key Laboratory of Respiratory Disease Research, Traditional Chinese Medical Hospital of Xinjiang Uygur Autonomous Region, Urumqi, 830011, Xinjiang, People’s Republic of China; 2CAS Key Laboratory of Bio-Medical Diagnostics, Suzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Sciences, Suzhou, 215163, People’s Republic of China; 3School of Public Health, Xinjiang Medical University, Urumqi, 830017, Xinjiang, People’s Republic of China; 4Department of Immunology, College of Basic Medicine, Xinjiang Medical University, Urumqi, 830011, Xinjiang, People’s Republic of China; 5Xinjiang Institute of Pediatrics, Xinjiang Hospital of Beijing Children’s Hospital, Children’s Hospital of Xinjiang Uygur Autonomous Region, Urumqi, 830011, Xinjiang, People’s Republic of China*These authors contributed equally to this workCorrespondence: Qifeng Li, Xinjiang Institute of Pediatrics, Xinjiang Hospital of Beijing Children’s Hospital, Children’s Hospital of Xinjiang Uygur Autonomous Region, Urumqi, 830054, People’s Republic of China, Tel +86-991 3056239, Fax +86-991 3056237, Email liqiqi521@sina.comBackground: Studying the potential etiology and pathogenesis of tuberculosis-associated chronic obstructive pulmonary disease (TOPD) from an autoimmunity perspective may provide insights into peripheral blood autoantibodies and immune cells, as well as their interactions.Methods: This study examined the serum autoantibody repertoire in healthy individuals, patients with chronic obstructive pulmonary disease (COPD), patients with pulmonary tuberculosis (TB), and TOPD patients using the HuProtTM protein chip. …”
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