The Interdisciplinary Task of Medicinal Chemists by Rudolf Giger

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ADMET for medicinal chemists : a practical guide / by Tsaioun, Katya, Kates, Steven A., 1961-

Asymmetric Organocatalysis: A Survival Guide to Medicinal Chemists by Efraim Reyes, Liher Prieto, Andrea Milelli

“…We aim to discuss the different activation modes observed for organocatalysts, examining, for each of them, the generally accepted mechanisms and the most important and developed reactions, that may be useful to medicinal chemists. For each of these types of organocatalytic activations, select examples from academic and industrial applications will be disclosed during the synthesis of drugs and natural products.…”
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Computational drug design : a guide for computational and medicinal chemists / by Young, David C., 1964-

User-friendly and industry-integrated AI for medicinal chemists and pharmaceuticals by Olga Kapustina, Polina Burmakina, Nina Gubina, Nikita Serov, Vladimir Vinogradov

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Computational Drug Design – A Guide for Computational and Medicinal Chemists by Monique Araújo de Brito

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The Medicinal Chemist's Dream: Faster Design of Better and Safer Drug Candidates by Marianne Reist, Laura Novaroli, Antoine Daina, Sophie Martel, Pierre-Alain Carrupt

“…The guidelines proposed here to use the best validated tools in the most suitable order will help the medicinal chemist to approach his dream, namely to be faster in the design of better and safer drug candidates. …”
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Computational drug design [electronics resource] : a guide for computational and medicinal chemists / by Young, David C., 1964-

Investigating the Prospects of ChatGPT in Training Medicinal Chemists and the Development of Novel Drugs by Michell O. Almeida, Artur C. G. Soares, Gustavo H. M. Sousa, Witor R. Ferraz, Gustavo Trossini

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ADME-Space: a new tool for medicinal chemists to explore ADME properties by Giovanni Bocci, Emanuele Carosati, Philippe Vayer, Alban Arrault, Sylvain Lozano, Gabriele Cruciani

“…Thus, the ADME-Space opens a new framework for the multi-parametric data analysis in drug discovery where all ADME behaviours of molecules are condensed in one map: it allows medicinal chemists to simultaneously monitor several ADME properties, to rapidly select optimal ADME profiles, retrieve warning on potential ADME problems and DDIs or select proper in vitro experiments.…”
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3-Hydroxyazetidine carboxylic acids: non-proteinogenic amino acids for medicinal chemists. by Glawar, A, Jenkinson, S, Thompson, A, Nakagawa, S, Kato, A, Butters, T, Fleet, G

“…The long-term stability of 3-hydroxyazetidine amides is established at acidic and neutral pH and implies their value as non-proteinogenic amino acid components of peptides, providing medicinal chemists with a new class of peptide isosteres. …”

Multi-target pharmacology: Possibilities and limitations of the skeleton key approach from a medicinal chemist perspective by Alan eTalevi

“…Prospective drug repositioning to treat comorbid conditions is an additional, overlooked application of multi-target ligands. While medicinal chemists usually rely on some version of the lock and key paradigm to design novel therapeutics, modern pharmacology has recognized that the long-term effects of a given drug on a biological system may depend not only on the specific ligand-target recognition events but also on the influence of the chronic administration of a drug on the cell gene signature. …”
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Inside the mind of a medicinal chemist: the role of human bias in compound prioritization during drug discovery. by Peter S Kutchukian, Nadya Y Vasilyeva, Jordan Xu, Mika K Lindvall, Michael P Dillon, Meir Glick, John D Coley, Natasja Brooijmans

“…Medicinal chemists' "intuition" is critical for success in modern drug discovery. …”
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A Comprehensive Update of Various Attempts by Medicinal Chemists to Combat COVID-19 through Natural Products by Ayesha Rafiq, Tooba Jabeen, Sana Aslam, Matloob Ahmad, Usman Ali Ashfaq, Noor ul Amin Mohsin, Magdi E. A. Zaki, Sami A. Al-Hussain

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Medicinal Chemists Don't Just Make Drugs – The Art of Developing Low Molecular Weight Imaging Agents in Switzerland by Yves P. Auberson

“… Radiolabeled molecular imaging agents are useful to study drug distribution, target engagement and disease progression in human patients. Medicinal chemists often develop them in parallel to drug discovery programs, to facilitate clinical development or to better understand physiological and pathological processes. …”
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Glass box and black box machine learning approaches to exploit compositional descriptors of molecules in drug discovery and aid the medicinal chemist by Robson, B, Cooper, R

“…The synthetic medicinal chemist plays a vital role in drug discovery. …”

Sage, <i>Salvia officinalis</i> L., Constituents, Hepatoprotective Activity, and Cytotoxicity Evaluations of the Essential Oils Obtained from Fresh and Differently Timed Dried Herb... by Hamdoon A. Mohammed, Hussein M. Eldeeb, Riaz A. Khan, Mohsen S. Al-Omar, Salman A. A. Mohammed, Mohammed S. M. Sajid, Mohamed S. A. Aly, Adel M. Ahmad, Ahmed A. H. Abdellatif, Safaa Yehia Eid, Mahmoud Zaki El-Readi

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Affiliation with Natural Products at KIB of Prof. Zhou Jun: On the Occasion of 80th Anniversary of Kunming Institute of Botany, CAS by Jiang-Miao Hu

“…Zhou Jun, Academician of Chinese Academy of Sciences (1999), is a phytochemist and medicinal chemist of China. He is one of the pioneers of Kunming Institute of Botany, CAS and a major founder of the State Key Laboratory of Phytochemistry and Plant Resources in West China. …”
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Therapeutic importance of synthetic thiophene by Rashmi Shah, Prabhakar Kumar Verma

“…It has made an indispensable anchor for medicinal chemists to produce combinatorial library and carry out exhaustive efforts in the search of lead molecules. …”
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Recent Advances in the Synthesis of Xanthines: A Short Review by Anandi Kapri, Nitin Gupta, Sumitra Nain

“…The data compiled in this review paper could help the medicinal chemist in designing new active compounds from the modification of the already existing compounds in the search for novel drug leads. …”
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