Pharmacokinetics-Driven Evaluation of the Antioxidant Activity of Curcuminoids and Their Major Reduced Metabolites—A Medicinal Chemistry Approach by Gábor Girst, Sándor B. Ötvös, Ferenc Fülöp, György T. Balogh, Attila Hunyadi

“…In this work, we aimed to perform a comparative evaluation of curcuminoids and their hydrogenated metabolites from a medicinal chemistry point of view, by determining a set of key pharmacokinetic parameters and evaluating antioxidant potential in relation to such properties.Reduced metabolites were prepared from curcumin and demethoxycurcumin through continuous-flow hydrogenation. …”
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Química Medicinal Moderna: desafios e contribuição brasileira Modern Medicinal Chemistry: challenges and Brazilian contribution by Lídia M. Lima

Subjects: “…medicinal chemistry…”
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Medicinal chemistry strategies towards the development of non-covalent SARS-CoV-2 Mpro inhibitors by Letian Song, Shenghua Gao, Bing Ye, Mianling Yang, Yusen Cheng, Dongwei Kang, Fan Yi, Jin-Peng Sun, Luis Menéndez-Arias, Johan Neyts, Xinyong Liu, Peng Zhan

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From Plant to Chemistry: Sources of Antinociceptive Non-Opioid Active Principles for Medicinal Chemistry and Drug Design by Rita Turnaturi, Silvia Piana, Salvatore Spoto, Giuliana Costanzo, Lorena Reina, Lorella Pasquinucci, Carmela Parenti

“…As the process of pain transmission and modulation is regulated by different peripheral and central mechanisms and neurotransmitters, medicinal chemistry continues to study novel ligands and innovative approaches. …”
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New dimensions in triazolo[4,3-a]pyrazine derivatives: The land of opportunity in organic and medicinal chemistry by Divya J. Jethava, Mayuri A. Borad, Manoj N. Bhoi, Prachi T. Acharya, Zeel A. Bhavsar, Hitesh D. Patel

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Synthesis of 3-Amino-4-substituted Monocyclic ß-Lactams—Important Structural Motifs in Medicinal Chemistry by Katarina Grabrijan, Nika Strašek, Stanislav Gobec

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Exploring the structural and functional requirements of Phyto-compounds and their synthetic scaffolds as anticancer agents: Medicinal chemistry perspective by Dipanjan Karati, Dileep Kumar

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Selective inhibitors of protozoan protein N-myristoyltransferases as starting points for tropical disease medicinal chemistry programs. by Andrew S Bell, James E Mills, Gareth P Williams, James A Brannigan, Anthony J Wilkinson, Tanya Parkinson, Robin J Leatherbarrow, Edward W Tate, Anthony A Holder, Deborah F Smith

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Medicinal Chemistry Friendliness of Pigments from Monascus-Fermented Rice and the Molecular Docking Analysis of Their Anti-Hyperlipidemia Properties by Nina Sun, Dominic Agyei, Dawei Ji

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Medicinal Chemistry of Anti-HIV-1 Latency Chemotherapeutics: Biotargets, Binding Modes and Structure-Activity Relationship Investigation by Yan-Kai Wang, Long Wei, Wei Hu, Pei-Xia Yu, Zhong Li, Hai-Peng Yu, Xun Li

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A critical review of benzimidazole: Sky-high objectives towards the lead molecule to predict the future in medicinal chemistry by Sabyasachi Banerjee, Sougata Mukherjee, Priyobrata Nath, Agnish Mukherjee, Souvik Mukherjee, S.K. Ashok Kumar, Sourav De, Subhasis Banerjee

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2^nd Anglo-Croatian Medicinal Symposium on Macrocycles Medicinal Chemistry and Beyond-the-Rule-of-Five by Vitomir Šunjić

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Second Joint Italian – Swiss Meeting on Medicinal Chemistry (ITCHMC 2005) Modena, September 12-16, 2005 by Wolfgang Froestl

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Cyclooxygenase-1 (COX-1) and COX-1 Inhibitors in Cancer: A Review of Oncology and Medicinal Chemistry Literature by Alessandra Pannunzio, Mauro Coluccia

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Second Joint French–Swiss Meeting on Medicinal Chemistry 39èmes Rencontres Internationales de Chimie Thérapeutique by Wolfgang Froestl

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Pathophysiological Role and Medicinal Chemistry of A_2A Adenosine Receptor Antagonists in Alzheimer’s Disease by Stefania Merighi, Pier Andrea Borea, Katia Varani, Fabrizio Vincenzi, Alessia Travagli, Manuela Nigro, Silvia Pasquini, R. Rama Suresh, Sung Won Kim, Nora D. Volkow, Kenneth A. Jacobson, Stefania Gessi

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From classic medicinal chemistry to state‐of‐the‐art interdisciplinary medicine: Recent advances in proteolysis‐targeting chimeras technology by Xuyang Zhao, Yifan Chen, Huang Su, Liqin Zhang

“…PROTAC technology is rapidly advancing from employing traditional medicinal chemistry methodologies to integrating state‐of‐the‐art chemical biology technologies, becoming a typical example of interdisciplinary medicine. …”
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The medicinal chemistry of Urtica dioica L.: from preliminary evidence to clinical studies supporting its neuroprotective activity by Prabhakar Semwal, Abdur Rauf, Ahmed Olatunde, Pooja Singh, Mohamed Y. Zaky, Md. Mozahidul Islam, Anees Ahmed Khalil, Abdullah S. M. Aljohani, Waleed Al Abdulmonem, Giovanni Ribaudo

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Targeting cannabinoid CB2 receptors in the Central Nervous System. Medicinal chemistry approaches with focus on neurodegenerative disorders by Gema Navarro, Paula Morales, Carmen Rodríguez-Cueto, Javier Fernández-Ruiz, Nadine Jagerovic, Rafael Franco

“…Differential localization of CB2 receptors in neural cell types and upregulation in neuroinflammation are keys to understand the therapeutic potential in inter alia diseases that imply progressive neurodegeneration. Medicinal chemistry approaches are now engaged to develop imaging tools to map receptors in the living human brain, to develop more efficacious agonists, and to investigate the possibility to develop allosteric modulators.…”
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[3 + n] Cycloaddition Reactions: A Milestone Approach for Elaborating Pyridazine of Potential Interest in Medicinal Chemistry and Optoelectronics by Dorina Amariucai-Mantu, Violeta Mangalagiu, Ionel I. Mangalagiu

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