Antimicrobially Active Zn(II) Complexes of Reduced Schiff Bases Derived from Cyclohexane-1,2-diamine and Fluorinated Benzaldehydes—Synthesis, Crystal Structure and Bioactivity by Bianka Oboňová, Ladislav Habala, Miroslava Litecká, Peter Herich, Andrea Bilková, František Bilka, Branislav Horváth

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Chemistry-led investigations into the mode of action of NAMPT activators, resulting in the discovery of non-pyridyl class NAMPT activators by Siyuan Tang, Miguel Garzon Sanz, Oliver Smith, Andreas Krämer, Daniel Egbase, Paul W. Caton, Stefan Knapp, Sam Butterworth

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Asymmetric α-Fluoroalkyl-α-Amino Acids: Recent Advances in Their Synthesis and Applications by Nathan Picois, Yazid Boutahri, Pierre Milbeo, Chiara Zanato, Nathalie Lensen, Grégory Chaume, Thierry Brigaud

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The Development of FAK Inhibitors: A Five-Year Update by Andrea Spallarossa, Bruno Tasso, Eleonora Russo, Carla Villa, Chiara Brullo

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From the Discovery of Targets to Delivery Systems: How to Decipher and Improve the Metallodrugs’ Actions at a Molecular Level by Ilaria Iacobucci, Sara La Manna, Irene Cipollone, Vittoria Monaco, Luisa Canè, Flora Cozzolino

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Chagas Disease Drug Discovery in Latin America—A Mini Review of Antiparasitic Agents Explored Between 2010 and 2021 by Ramon G. de Oliveira, Luiza R. Cruz, María C. Mollo, Luiz C. Dias, Jadel M. Kratz

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O USO DE SOFTWARES LIVRES EM AULA PRáTICA SOBRE FILTROS MOLECULARES DE BIODISPONIBILIDADE ORAL DE FáRMACOS by Gabriela dos Santos Rodrigues, Júnior A Avelino, Ariane L. N. Siqueira, Luciana F. P. Ramos, Gabriela B. dos Santos

Subjects: “…pharmaceutical and medicinal chemistry…”
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Recent Applications of the Multicomponent Synthesis for Bioactive Pyrazole Derivatives by Diana Becerra, Rodrigo Abonia, Juan-Carlos Castillo

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A Consensus Compound/Bioactivity Dataset for Data-Driven Drug Design and Chemogenomics by Laura Isigkeit, Apirat Chaikuad, Daniel Merk

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Novel Quinoline Compounds Active in Cancer Cells through Coupled DNA Methyltransferase Inhibition and Degradation by Clemens Zwergel, Rossella Fioravanti, Giulia Stazi, Federica Sarno, Cecilia Battistelli, Annalisa Romanelli, Angela Nebbioso, Eduarda Mendes, Alexandra Paulo, Raffaele Strippoli, Marco Tripodi, Dany Pechalrieu, Paola B. Arimondo, Teresa De Luca, Donatella Del Bufalo, Daniela Trisciuoglio, Lucia Altucci, Sergio Valente, Antonello Mai

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Freely available compound data sets and software tools for chemoinformatics and computational medicinal chemistry applications [v1; ref status: indexed, http://f1000r.es/Mu9krs] by Ye Hu, Jurgen Bajorath

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Novel Strategies in C-H Oxidations for Natural Product Diversification—A Remote Functionalization Application Summary by Huang Junrong, Huang Junrong, Yang Min, Dai Chuan, Zhou Yajun, Fang Huilong, Zhu Lizhi, Zhu Lizhi, Yin Feng, Yin Feng, Li Zigang, Li Zigang

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Transfer and Multi-task Learning in QSAR Modeling: Advances and Challenges by Rodolfo S. Simões, Vinicius G. Maltarollo, Patricia R. Oliveira, Kathia M. Honorio, Kathia M. Honorio

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Technologies for Direct Detection of Covalent Protein–Drug Adducts by Elma Mons, Robbert Q. Kim, Monique P. C. Mulder

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Effect of D-Alpha Tocopherol Therapy towards Malondialdehyde Level and Histology of Kidney in Rattus norvegicus with MLD-STZ Induction by Marissa Agnestiansyah Mahardhian, Aulanni’am Aulanni'am, Chanif Mahdi

Subjects: “…Medicinal Chemistry…”
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Ruthenium(II) and Platinum(II) Complexes with Biologically Active Aminoflavone Ligands Exhibit In Vitro Anticancer Activity by Małgorzata Fabijańska, Maria M. Kasprzak, Justyn Ochocki

Subjects: “…medicinal chemistry…”
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The Diels‐Alder Approach towards Cannabinoid Derivatives and Formal Synthesis of Tetrahydrocannabinol (THC) by Dr. Thomas Hurrle, Dr. Franziska Gläser, Dr. Manuel C. Bröhmer, Dr. Martin Nieger, Prof. Dr. Stefan Bräse

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Efficient Fmoc-Protected Amino Ester Hydrolysis Using Green Calcium(II) Iodide as a Protective Agent by Renaud Binette, Michael Desgagné, Camille Theaud, Pierre-Luc Boudreault

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Comparisons of Halogenated β-Nitrostyrenes as Antimicrobial Agents by Hugh Cornell, Thu Nguyen, Gina Nicoletti, Neale Jackson, Helmut Hügel

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Investigating material basis and molecular mechanism of Qing Cuo formula in the treatment of acne based on animal experiments, UPLC-LTQ-Orbitrap-MS and network pharmacology by Yanqi Cao, Jinfeng Liang, Chunguo Wang, Xuejie Bao, Siqi Li, Qi Liu, Bin Zeng, David Humberto Lopez, Ruoxi Yu

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